Bioceramics: From Macro to Nanoscale

From Macro to Nanoscale
Elsevier (Verlag)
  • erscheint ca. am 1. September 2020
  • Buch
  • |
  • Softcover
  • |
  • 990 Seiten
978-0-08-102999-2 (ISBN)
Biologically functional ceramic materials have been known about for several decades, like phosphate cements and gypsum, and they are within the zeroth generation. Modern and artificially synthesized bioceramics include amorphous materials in the Bioglass® family that were developed in the early 1970's and derivative glass ceramics such as Bioverit® and Cerabone A-W® that came in 1980's. They are from the 2nd generation of materials, and mostly applicable to bone replacement or bone defect fillers. Since the late 1990's, newer technologies have been introduced to the biologically functional material fields; they are the syntheses of organic-inorganic hybrids of micro- and macroscopic scales as well as nano-scales, organic fragment-covered ceramic particles of varied sizes, with light-controlling abilities to modify the frequency of light, in addition synthesis of high strength and high-tribological durability that had not been available before. With the advent of additive manufacturing technology employing lasers, electron beams, and printers, clinical materials of complicated porous structures are now easily prepared. These materials are of the 3rd generation.This book will cover almost all kinds of such 3rd generation ceramic and ceramic-related biomaterials.This book conveys the current state-of-the-art on the science and technology of bioceramics, from nano-size dots or particles to macro-scale architectures, of a wide range of constitutions including quantum dots with peptide fragments, meso-scale therapeutic particles designed to involve drugs or genes, mesoporous organic-inorganic hybrids, nano-structured oxide layers on metals and alloys.

- Comprehensively covers all aspects (research/experimental and commercial products) related to the latest progresses in bioceramic science, technology and applications, with emphasis on nanobioceramics
- Pulls together a broad range of materials, concepts, and technologies based on nanomaterials
- Features novel preparation procedures like additive manufacturing (3-D printing and related techniques) that have also been introduced and practiced for forming complicated architectures
- Features innovative 3rd generation ceramic and ceramic-related biomaterials
  • Englisch
  • London
  • |
  • Großbritannien
Elsevier Health Sciences
  • Für Beruf und Forschung
  • |
  • academic and industrial researchers, materials scientists, chemists, clinicians and biologists and engineers working in ceramic materials for biomedical applications
Approx. 350 illustrations (80 in full color)
  • Höhe: 229 mm
  • |
  • Breite: 152 mm
978-0-08-102999-2 (9780081029992)
Dr. Roger Narayan is a Professor in the Joint Department of Biomedical Engineering at the University of North Carolina and North Carolina State University. He is an author of over two hundred publications as well as several book chapters on processing of biomedical materials. He currently serves as an editorial board member for several academic journals, including as editor-in-chief of Medical Devices & Sensors (Wiley) and associate editor of Applied Physics Reviews (AIP Publishing). Dr. Narayan has also edited several books, including the textbook Biomedical Materials (Springer), the handbook Materials for Medical Devices (ASM International), and The Encyclopedia of Biomedical Engineering (Elsevier). He has previously served as director of the TMS Functional Materials Division and the ASM International Emerging Technologies Awareness Committee; he currently serves as chair of the American Ceramic Society Bioceramics Division. As the 2016-7 ASME Swanson Fellow, Dr. Narayan worked with America Makes, the US national additive manufacturing institute, on several activities to disseminate additive manufacturing technology, including the development of an workforce/education/outreach roadmap for additive manufacturing, and the development of a repository containing educational materials related to additive manufacturing. Dr. Narayan has received several honors for his research activities, including the NCSU Alcoa Foundation Engineering Research Achievement Award, the University of North Carolina Jefferson-Pilot Fellowship in Academic Medicine, the National Science Faculty Early Career Development Award, the Office of Naval Research Young Investigator Award, and the American Ceramic Society Richard M. Fulrath Award. He has been elected as Fellow of AAAS, ASM International, AIMBE, and American Ceramic Society.
1. Introduction

Part 1: Nanostructured surfaces, Surface biomedical modifications of materials 2. Importance of nano-structured surfaces 3. Alginic acid or Ti-O organics for surface coating on SSA 4. Hemostatic effects of 45S5 sol-gel glass 5. Nano-surface control, 3-D oxides 6. RGD peptides on biomaterials: Advantages of RGD peptides for directing cell association with biomaterials. 7. Nano-structured TiO2 layers on Ti for bone-bonding 8. Computer simulation of the apatite crystallization on glass surface like

Part 2: Nanoparticles for Drug delivery applications, Sensing, and Diagnostics 9. Magnetite/silica nanoparticles 10. Plasmon and photothermal therapy 11. Biological functions of cerium oxide nanoparticles 12. Plasmon from Fe/Au nanoparticles and bioimaging 13. Near Infra-Red (NIR) excitation of quantum dots for biosensing and imaging 14. NIR excitation of rare earth ions for diagnosis and bioimaging 15. Synthesis and applications of cerasomes: ceramic nano particles with ceramic core and a liposome-like shell) 16. Nano-machines for cancer therapy 17. Quantum dots with nucleic acids shell for biosensing 18. Antibacterial activity of Ag-silica nanoparticles 19. Plasmon for photothermal therapy 20. Magnetic heating with ceramic nanoparticles for nanothermometry,

Part 3: Nano-composites 21. Trial of preparing collagen-alagonite nano-composites 22. Mg phosphate nanosheets 23. Glass ionomer cement for dental applications

Part 4: Nano-scale effects on bioceramics; molecular nanostructure control 24. Grain size & strength of HAp ceramics 25. Interlayer distance control for layer-structured ceramics 26. Surface modification of apatite ceramics by Ion irradiation 27. Dissolution control of silicate glasses; exploring new bioactive glasses 28. Nano F-apatite formation on DCPD 29. Bone structure and formation: A new perspective 30. Sol-gel preparation of titanium oxide and hydroxyapatite microparticles for blood purification 31. Nano-porosity and cell responses 32. Posner-Bett particles and bone-nucleation. 33. The role of prenucleation clusters in surface-induced calcium phosphate crystallization

Part 5: Bioinert bulk ceramics, load bearing ceramics 34. Ceramics for joints: Alumina, zirconia, ZrO2-touhened alumina (like BioloxR)

Part 6: Additive manufacturing, amorphous materials 35. Porous bone repair architecture with 13-93 glass 36. New glass composition survey

Part 7: Ceramics in dental applications; Glass-ceramics, Cements, Glass-Ionomers 37. Glass ceramics for dental crown 38. Modern glass ionomer cement 39. Novel calcium phosphate cements

Part 8: Bioactive ceramics 41. Bioactive ceramics: past and future

Part 9: Biomimetic/bioinspired materials 42. [PILP and bone regeneration]

Part 10: Commercial or soon to be commercialized hydroxyapatite coating methods 43. TBC

Part 11: Radiotherapy applications 44. Y- and Dy-containing glass microparticles for cancer therapy 45. P-implanted glass microparticles for cancer therapy

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