Structural and Molecular Basis of Skeletal Muscle Disease
Published in May 2006
Software
Digital media
312 pages
978-3-9522313-0-2 (ISBN)
Description
Available as a CD-ROM only, this title is a groundbreaking effort in myological text as its organisation does not follow traditional guidelines. The diseases are grouped into major categories that are characterised by a common molecular or functional feature rather than a traditional designation. It covers all major myopathies and is focused on molecular genetics, pathophysiology, and structural changes. Salient features of the clinical phenotype and potential methods for molecular therapy are also presented.
More details
Language
English
Place of publication
Basle
Switzerland
Target group
Professional and scholarly
Target Readership: neurologists, neuropathologists, general pathologists, geneticists, medical specialists dealing with muscle diseases, residents, and molecular scientists.
Illustrations
CD-ROM
575
Dimensions
Height: 250 mm
Width: 200 mm
Weight
666 gr
ISBN-13
978-3-9522313-0-2 (9783952231302)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Person
Volume EditorGeorge KarpatiAdvisory EditorsMaria MolnarHans H. GoebelKiichi ArahataAlan E. H. EmeryEric HoffmanEric Shoubridge
Content
1. General pathological, immunopathological, and genetic background of skeletal muscle disorders 2. Diseases associated with sarcolemmal and extracellular matrix defects 3. Diseases associated with myonuclear abnormalities 4. Myofibrillar and internal cytoskeletal proteins 5. Diseases associated with ion channel and ion transporter defects 6. Myopathies based on complex molecular defects 7. Developmental disorders of skeletal muscle 8. Disorders of catabolic mechanisms 9. Neuromuscular transmission defects 10. Myopathies affecting fuel and energy metabolism 11. Dysimmune and infectious myopathies 12.Toxic and iatrogenic disorders 13. Effects of chronic denervation and disuse on muscle 14. Endocrine disorders and myotrophic molecules 15. Miscellaneous myopathies 16. Neuromuscular resources on the Internet 17. The principles of therapies and prevention based on cellular and molecular mechanisms of muscle disease