Computer Modelling in Molecular Biology
Published on 19. December 2007
Software
Other digital
259 pages
978-3-527-61533-9 (ISBN)
Description
This book supplies an application-oriented introduction to molecular simulation techniques used to study a wide range of problems in molecular biology. Each chapter focuses in detail on one kind of application, including the scientific background, the appropriate methodology and the relationship to experimental results. The book contains many areas of interest to basic and industrial scientists, including: flexibility of peptides; protein-peptide interactions; ion translocation across membranes; modelling protein and nucleic acid conformations; stability of mutant proteins; and, modelling conformational transitions. Currently the only up-to-date compilation available, this book enables readers to get an overview of the methods and how they are used in various specialized applications without having to search for them in a large number of papers in different journals.
More details
Language
English
Place of publication
Weinheim
Germany
Target group
Professional and scholarly
Dimensions
Height: 245 mm
Width: 178 mm
Thickness: 42 mm
Weight
660 gr
ISBN-13
978-3-527-61533-9 (9783527615339)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Julia M. Goodfellow
Computer Modelling in Molecular Biology
E-Book
07/2008
1st Edition
Wiley-Blackwell
€115.99
Available for download
Content
Colour Illustrations Introduction to Computer Simulation: Methods and Applications (Julia M. Goodfellow and Mark A. Williams) Modelling Protein Structures (Tim J. P. Hubbard and Arthur M. Lesk) Molecular Dynamics Simulations of Peptides (D. J. Osguthorpe and P. K. C. Paul) Molecular Dynamics and Free Energy Calculations Applied to the Enzyme Barnase and One of its Stability Mutants (Shoshana J. Wodak, Daniel van Belle, and Martine Prevost) The Use of Molecular Dynamics Simulations for Modelling Nucleic Acids (E. Westhof, C. Rubin-Carrez, and V. Fritsch) Theory of Transport in Ion Channels (Benoit Roux) Molecular Modelling and Simulations of Major Histocompatibility Complex Class I Protein-Peptide Interactions (Christopher J. Thorpe and David S. Moss) Path Energy Minimization: A New Method for the Simulation of Conformational Transitions of Large Molecules (Oliver S. Smart) Index