Tumor Necrosis Factor

Table of Contents; Tumor Necrosis Factor: Methods and Protocols; Edited by Angelo Corti and Pietro Ghezzi; 1 Tumor Necrosis Factor as a Pharmacological Target Pietro Ghezzi and Antony Cerami; 2 Production and Characterization of Recombinant Human and Murine TNF Flavio Curnis and Angelo Corti; 3 Purification of TNF binding proteins Hartmut Engelmann, Dani Aderka and David Wallach; 4 Production and Characterization of Receptor Specific TNF Muteins Paul Ameloot and Peter Brouckaert; 5 TNF[alpha] Promoter Polymorphysms Silvia Fargion, Luca Valenti, Paola Dongiovanni, and Anna Ludovica Fracanzani; 6 Detection of TNF and TNF Receptor mRNA in Cells and Tissues Roberto Furlan, Giuliana Salani, Alessandra Bergami, and Gianvito Martino; 7 Immuno-Histochemical Localization of TNF[alpha] and its Receptors Paolo Bigini and Tiziana Mennini; 8 TNF Signaling: Key Protocols Marta Muzio and Simona Saccani; 9 More Than One Way to Die: Methods to Determine TNF-Induced Apoptosis and Necrosis Tom Vanden Berghe, Geertrui Denecker, Greet Brouckaert, Dmitri Krysko, Katharina Dherde, and Peter Vandenabeele; 10 Assessment of the Endothelial TNF[alpha]-Induced Damage Through the Loss of its Barrier Function Elisabetta Ferrero; 11 Genetic Engineering in the Mouse: Tuning TNF/TNF-R Expression Eleni Douni, Maria Alexiou, and George Kollias; 12 Animal Models of TNF[alpha]-Mediated Diseases of the Central Nervous System Roberto Furlan, Pia Villa, Giorgio Senaldi, and Gianvito Martino; 13 In Vivo Vascular Leakage Assay Maria Elena Ferrero; 14 Animal Models of Endotoxic Shock Pia Villa and Pietro Ghezzi; 15 Collagen-Induced Arthritis as a Model for Rheumatoid Arthritis Richard O. Williams; 16 Miocardial Infarction: Animal Models Stefano Chimenti, Eleonora Carlo, Serge Masson, Antonio Bai, and Roberto Latini; 17 Tumor Vascular Therapy with TNF: Critical Review on Animal Models Timo L. M. ten Hagen and Alexander M.M. Eggermont; 18 Strategies for Improving the Anti-Neoplastic Activity of TNF by Tumor Targeting Angelo Corti