Inflammatory Process

ContributorsPrefaceChapter 1 The Experimental Approach to Inflammation I. Introduction II. The Gross Pathology of Inflammation III. The Light Microscope and the Study of Inflammation IV. Bacteriology and Immunology V. Phagocytosis VI. Chemotaxis VII. The Physiologic Approach to Problems of Inflammation VIII. Chemical Mediators of Inflammation IX. The Electron Microscope and Changes in Ultrastructure X. Conclusion ReferencesChapter 2 Some Ultrastructural and Biochemical Consequences of Cell Injury I. Introduction II. The Cytoplasm III. The Nucleus IV. Concluding Remarks ReferencesChapter 3 The Ultrastructural Basis of Capillary Permeability I. Introduction II. Permeability of Capillaries III. Capillary Structure IV. Discussion of Various Mechanisms Proposed for the Control of Capillary Permeability V. Summary and Conclusions ReferencesChapter 4 Microvascular Aspects of Tissue Injury I. General Aspects of Reaction II. Specific Components III. Summary Statement ReferencesChapter 5 The Sticking and Emigration of White Blood Cells in Inflammation I. Introduction II. History of the Problem III. Fate of Emigrated Cells in the Extravascular Tissues IV. The Influence of pH on the Emigration of White Cells V. Relationship Between White Cell Sticking and Vascular Permeability VI. Chemotaxis VII. Electrochemical Factors VIII. Summary ReferencesChapter 6 Neutrophil and Eosinophil Leucocytes I. Introduction II. Neutrophil Leucocytes III. The Eosinophil Leucocyte ReferencesChapter 7 The "Life History" and Functions of Lymphocytes I. Introduction II. General Description of Lymphocytes III. Origins and Early Development of Lymphocytes IV. "Life Span" and Turnover of Small Lymphocytes V. Recirculation of Small Lymphocytes VI. Alleged Transformations of Lymphocytes into Other Cell Types VII. The Proposed Trephocytic Function of Lymphocytes VIII. The Immunologic Activity of Lymphocytes IX. Summary and Conclusions ReferencesChapter 8 The Metabolism and Physiology of the Mononuclear Phagocytes I. Introduction and Historical Development II. Nomenclature III. Morphology IV. Distribution V. Origin VI. Development and Differentiation VII. Biochemistry and Metabolism VIII. The Inflammatory Response IX. Functional Properties X. Special Relationships to Bacteria and Viruses ReferencesChapter 9 Structural and Biochemical Characteristics of Mast Cells I. Introduction II. Origin and Distribution of Mast Cells III. Normal Tissue Mast Cells; Neoplastic Mast Cells IV. Mast Cell Cytology V. Biochemistry of the Mast Cells VI. Functional View of the Tissue Mast Cell VII. Mast Cells in Pathologic Disorders VIII. Concluding Remarks ReferencesChapter 10 Chemical Mediators. I I. Introduction II. Early Vascular Events in Inflammation III. Endogenous Mediators of the Vascular Events IV. Evidence for the Natural Role of Proteases, Polypeptides, and Amines in the Inflammatory Process V. Investigations of Other Possible Mediators in Inflammation VI. Conclusions ReferencesChapter 11 Chemical Mediators. II I. Histamine II. 5-Hydroxytryptamine III. Epinephrine and Norepinephrine IV. Conclusions ReferencesChapter 12 The Role of Lysosomes in Tissue Injury I. The Lysosome Concept II. Vitamin A and Lysosomes III. Stabilization of Lysosomes by Cortisone IV. Ultraviolet Light and Lysosomes V. Lysosomes in Endotoxin Shock VI. Streptolysins and Lysosomes VII. Leucocyte Granules and Tissue Injury VIII. Lysosomes and Tissue Necrosis IX. Summary ReferencesChapter 13 Hemostatic Mechanisms in Tissue Injury I. Introduction II. The Hemostatic Plug III. Vascular and Tissue Factors in Hemostasis IV.