
Multicomponent Reactions
Description
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From the contents:
* Organoboron compounds
* Free-radical mediated multicomponent coupling reactions
* Applications in drug discovery
* Metal catalyzed reactions
* Total synthesis of natural products
* Asymmetric isocyanide-based reactions
* The Biginelli reaction
* Asymmetric isocyanide-based reactions
* The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and related transformations
* Catalytic asymmetric reactions
* Algorithm based methods for discovering novel reactions
* Post-condensation modifications of the Passerini and Ugi reactions
An essential reference for organic and catalytic chemists, and those working in organometallics both in academia and industry.
Reviews / Votes
"...it will be useful to the specialists in the field. Naturally, librarians may also like to acquire this book."Angewandte Chemie
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Persons
Dr. Zhu has published over 110 research papers.
Hugues Bienaymé gained his PhD in organic chemistry at the university of Paris under Professor A. Lubineau, than took up a post-doctoral position at the University of Geneva under the supervision of Professor W. Oppolzer. He joined Rhône-Poulenc (Aventis) in 1991 where he held various research positions in process and discovery chemistry. From 1995 to 2000 he was head of the combinatorial and discovery chemistry group for the company's central research department, developing multi-component condensations as a general tool to accelerate drug discovery. In 1996 the company awarded him the title "associate professor".
In 2001, Dr. Bienaymé founded Chrysalon, a start-up in the field of combinatorial chemistry. After the company's merger in 2003, he became managing director and CSO of Urogene, a biotech company dedicated to discovering new drugs in urology.
Hugues Bienaymé is the author or co-author of more than 40 publications and patents.
Content
Free-Radical Mediated Multicomponent Coupling Reactions
Applications of Multicomponent Reactions in Drug Discovery - Lead Generation to Process Development
The Discovery of New Isocyanide Based Multicomponent Reactions
Metal catalyzed Multicomponent Reactions
Multicomponent Reactions in the Total Synthesis of Natural Products
Asymmetric Isocyanide-Based Multicomponent Reactions
The Biginelli reaction
Asymmetric Isocyanide-Based Multicomponent Reactions
The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and Related Transformations
Catalytic Asymmetric Multicomponent Reactions
Algorithm Based Methods for the Discoverey of Novel Multicomponent Reactions
Post-condensation Modifications of the Passerini and Ugi Reactions
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