
Machine Learning in Medical Imaging
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This book constitutes the proceedings of the 6th International Workshop on Machine Learning in Medical Imaging, MLMI 2015, held in conjunction with MICCAI 2015, in Munich in October 2015.
The 40 full papers presented in this volume were carefully reviewed and selected from 69 submissions. The workshop focuses on major trends and challenges in the area of machine learning in medical imaging and present works aimed to identify new cutting-edge techniques and their use in medical imaging.
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Content
- Intro
- Preface
- Organization
- Contents
- Segmentation of Right Ventricle in Cardiac MR Images Using Shape Regression
- 1 Introduction
- 2 Methodology
- 2.1 Data Augmentation
- 2.2 Feature Extraction
- 2.3 Training the Regressors
- 2.4 Prediction
- 3 Experiments
- 4 Conclusions
- References
- Visual Saliency Based Active Learning for Prostate MRI Segmentation
- 1 Introduction
- 2 Image Features
- 3 Semi Supervised Learning With Random Forests
- 4 SSL-AL Based Segmentation From MR Images
- 4.1 AL Query Strategy
- 4.2 Random Walks and Most Salient Node
- 4.3 Graph Cut Segmentation
- 5 Experiments and Results
- 5.1 Results on MICCAI PROMISE12 Online Challenge Dataset
- 5.2 Savings in Labeling Effort and Time
- 6 Discussion and Conclusion
- References
- Soft-Split Random Forest for Anatomy Labeling
- 1 Introduction
- 2 Random Forest
- 3 Proposed Metho od
- 3.1 Soft-Split Random Forest
- 3.2 Haar-Features Based Context Model (HCM)
- 4 Experiments
- 5 Conclusion
- References
- A New Image Data Set and Benchmark for Cervical Dysplasia Classification Evaluation
- 1 Introduction
- 2 The Image Data Set for CIN Classification
- 3 Seven Classifiers for Comparison
- 4 Experiments
- 4.1 Results on Balanced Datasets
- 4.2 Results on Imbalanced Datasets
- 4.3 Cervigram Based RandomForest (RF) vs. Pap and HPV Tests
- 5 Conclusions
- References
- Machine Learning on High Dimensional Shape Data from Subcortical Brain Surfaces: A Comparison of Feature Selection and Classification Methods
- 1 Introduction
- 2 Methods
- 2.1 Subjects
- 2.2 High Dimensional Shape Features
- 2.3 Feature Selection
- 2.4 Classifiers
- 3 Results
- 3.1 Feature Selection Subsets
- 3.2 Classification Results
- 4 Discussion
- References
- Node-Based Gaussian Graphical Model for Identifying Discriminative Brain Regions from Connectivity Graphs
- 1 Introduction
- 2 Methods
- 2.1 Gaussian Graphical Model
- 2.2 Row-Column Overlap Norm
- 2.3 Node-Based Gaussian Graphical Model
- 2.4 Group Analysis with NBGGM
- 3 Materials
- 4 Results and Disc cussion
- 5 Conclusions
- References
- BundleMAP: Anatomically Localized Features from dMRI for Detection of Disease
- 1 Introduction
- 2 Related Work
- 3 BundleMAP for Tract-Based Feature Extraction
- 3.1 Tracking the Bundles
- 3.2 Eliminating Fibers from Adjacent Bundles
- 3.3 Manifold Learning of BundleMAP Coordinates
- 3.4 Feature Extraction and Selection
- 4 Results
- 4.1 Classification Accuracy
- 4.2 Anatomical Interpretability
- 4.3 Selecting the Number of Bins
- 5 Conclusion
- References
- FADR: Functional-Anatomical Discriminative Regions for Rest fMRI Characterization
- 1 Introduction
- 2 Functional-Anatomical Discriminative Regions Method
- 3 Experiments and Results
- 4 Conclusions
- References
- Craniomaxillofacial Deformity Correction via Sparse Representation in Coherent Space
- 1 Introduction
- 2 Method
- 2.1 Sparse Representat tion (SR)-Based Jaw Prediction
- 2.2 Mapping-Based Sparse Representation for Jaw Prediction
- 3 Experiments
- 3.1 Dataset
- 3.2 Measurement
- 3.3 Quantitative Results
- 3.4 Qualitative Compa arison
- 4 Conclusion
- References
- Nonlinear Graph Fusion for Multi-modal Classification of Alzheimer's Disease
- 1 Introduction
- 2 Methods
- 2.1 Graph Construction
- 2.2 Nonlinear Graph Fusion
- 2.3 Classification
- 3 Experiments and Results
- 3.1 Influence of k
- 3.2 Comparison with Other Methods
- 4 Discussion and Conclusion
- References
- HEp-2 Staining Pattern Recognition Using Stacked Fisher Network for Encoding Weber Local Descriptor
- 1 Introduction
- 2 Materials
- 3 Methods
- 3.1 Weber's Law
- 3.2 The First Layer FN
- 3.3 The Second Layer FN
- 4 Experimental Results
- 5 Conclusions
- References
- Supervoxel Classification Forests for Estimating Pairwise Image Correspondences
- 1 Introduction
- 2 Methods
- 2.1 Problem Formulation
- 2.2 Random Forests
- 2.3 Supervoxel Classification Forest (SVF)
- 3 Experiments and Results
- 4 Discussion and Conclusion
- References
- Non-rigid Free-Form 2D-3D Registration Using Statistical Deformation Model
- 1 Introduction
- 2 Materials and Methods
- 2.1 Training Process
- 2.2 Reconstruction Process
- 3 Experiments and Results
- 4 Discussions and Conclusions
- References
- Learning and Combining Image Similarities for Neonatal Brain Population Studies
- 1 Introduction
- 2 Methods
- 3 Data and Results
- 4 Conclusions
- References
- Deep Learning, Sparse Coding, and SVM for Melanoma Recognition in Dermoscopy Images
- 1 Introduction
- 2 Related Work
- 3 Methods
- 3.1 Dataset
- 3.2 Deep Learning Modeling Components
- 3.3 Classical Modeling Approach
- 4 Results
- 4.1 Ensembles of Low-Level Visual Features
- 4.2 Convolutional Neural Networks
- 4.3 Sparse Coding
- 4.4 Fusions
- 5 Conclusion
- References
- Predicting Standard-Dose PET Image from Low-Dose PET and Multimodal MR Images Using Mapping-Based Sparse Representation
- 1 Introduction
- 2 Patch-Based Sparse Representation (SR)
- 3 Proposed Method
- 3.1 Mapping Based SR
- 3.2 Incremental Refinement
- 3.3 Patch Selection Based Dictionary Construction
- 4 Experiments
- 4.1 Comparison of
- 4.2 Efficacy of the Incremental Refinement Strategy
- 5 Conclusion
- References
- Boosting Convolutional Filters with Entropy Sampling for Optic Cup and Disc Image Segmentation from Fundus Images
- 1 Introduction
- 2 Method
- 2.1 Boosting Convolutional Filters
- 2.2 Classification
- 3 Experimental Results
- 3.1 Segmentation Performance
- 4 Discussion and Conclusion
- References
- Brain Fiber Clustering Using Non-negative Kernelized Matching Pursuit
- 1 Introduction
- 2 Kernelized Dictionary Learning for Clustering
- 2.1 Dictionary Learning Using Kernelized k-means
- 2.2 Non-negative Kernelized Sparse Clustering
- 3 Experiments
- 4 Conclusion
- References
- Automatic Detection of Good/Bad Colonies of iPS Cells Using Local Features
- 1 Introduction
- 2 Methods
- 2.1 Extracting Local Features from iPS Cell Colony Images
- 2.2 Cell Colony Classification with a Kernelized Novelty Detector
- 2.3 Cell Colony Classification with 2-Class Support Vector Machine
- 2.4 Cell Colony Classification with the Bag-of-Features Approach
- 3 Experimental Results
- 4 Conclusion
- References
- Detecting Abnormal Cell Division Patterns in Early Stage Human Embryo Development
- 1 Introduction
- 2 Methodology
- 3 Experiments
- 4 Conclusion
- References
- Identification of Infants at Risk for Autism Using Multi-parameter Hierarchical White Matter Connectomes
- 1 Introduction
- 2 Multi-Parameter Hierarchical Connectome Classification
- 2.1 Overview
- 2.2 ROI Parcellation
- 2.3 Hierarchical Conne ectomes
- 2.4 Multi-Kernel Classification
- 3 Experiment Results
- 3.1 Subjects and Data Processing
- 3.2 Experiment Setting
- 3.3 Classification Results
- 3.4 Most ve Discriminativ Connections
- 4 Conclusion
- References
- Group-Constrained Laplacian Eigenmaps: Longitudinal AD Biomarker Learning
- 1 Introduction
- 2 Manifold Learning MR Image Based Features
- 2.1 Multilevel Feature Selection
- 2.2 Local Binary Patterns
- 2.3 Laplacian Eigenmaps
- 3 Experiments and Results
- 4 Discussion and Future Work
- References
- Multi-atlas Context Forests for Knee MR Image Segmentation
- 1 Introduction
- 2 Method
- 2.1 Multi-atlas Context Forests
- 2.2 Bone and Cartilage Segmentation
- 3 Experimental Results
- 3.1 Bone Segmentation
- 3.2 Cartilage Segmentation
- 4 Conclusions
- References
- Longitudinal Patch-Based Segmentation of Multiple Sclerosis White Matter Lesions
- 1 Introduction
- 2 Materials and Method
- 2.1 Dataset
- 2.2 Method
- 2.3 Dictionary Modification
- 3 Results
- 3.1 Number of Reference Images
- 3.2 Quantitative Evaluation
- 4 Discussion
- References
- Hierarchical Multi-modal Image Registration by Learning Common Feature Representations
- 1 Introduction
- 2 Method
- 2.1 Learning Common Feature Representations via Kernel CCA
- 2.2 Hierarchical Feature-Based Multi-modal Image Registration
- 3 Experiments
- 3.1 MR/CT Prostate Image Registration
- 3.2 Image Registration for Infant Brain MR Images in the First Year of Life
- 4 Conclusion
- References
- Semi-automatic Liver Tumor Segmentation in Dynamic Contrast-Enhanced CT Scans Using Random Forests and Supervoxels
- 1 Introduction
- 2 Methodology
- 2.1 Traditional Approach: Single-Phase Voxel-Wise Random Forest
- 2.2 Proposed Methodology: Multi-phase Cluster-Wise Random Forest
- 3 Results
- 4 Conclusion
- References
- Flexible and Latent Structured Output Learning
- 1 Introduction
- 2 Methodology
- 2.1 Inference and Learning
- 2.2 The Flexible and Latent Structure G = (V,E)
- 3 Materials and Methods
- 4 Results
- 5 Discussion and Conclusion
- References
- Identifying Abnormal Network Alterations Common to Traumatic Brain Injury and Alzheimer's Disease Patients Using Functional Connectome Data
- 1 Introduction
- 2 Materials and Methods
- 2.1 Participants
- 2.2 rsfMRI Data Acquisition
- 2.3 rsfMRI Data Preprocessing
- 2.4 Functional Connectome Reconstruction
- 2.5 Node-Based Connectome Feature Vector
- 2.6 Alzheimer's Disease Classification Pipeline
- 2.7 TBI Connectome Classification Using AD Pipeline
- 3 Results
- 3.1 AD Classification Results
- 3.2 TBI Connectome Classification Resutls Using AD Pipeline
- 4 Discussion
- References
- Multimodal Multi-label Transfer Learning for Early Diagnosis of Alzheimer's Disease
- 1 Introduction
- 2 Method
- 2.1 Multi-domain Multi-label Feature Selection
- 2.2 Multimodal Regression and Classification
- 3 Experiments
- 3.1 Experimental Settings
- 3.2 Results
- 4 Conclusion
- References
- Soft-Split Sparse Regression Based Random Forest for Predicting Future Clinical Scores of Alzheimer's Disease
- 1 Introduction
- 2 Method
- 2.1 Random Forest
- 2.2 Sparse Regression in Random Forest
- 2.3 Soft Split in Random Forest
- 3 Experiment Results
- 4 Conclusion
- References
- Multi-view Classification for Identification of Alzheimer's Disease
- 1 Introduction
- 2 Approach
- 2.1 Notations
- 2.2 Image Processing
- 2.3 Multi-view Learning
- 2.4 AD Classification
- 3 Experimental Results and Discussion
- 3.1 Experimental Setting
- 3.2 Performance and Discussion
- 4 Conclusion
- References
- Clustering Analysis for Semi-supervised Learning Improves Classification Performance of Digital Pathology
- 1 Introduction
- 2 Related Works
- 3 Image Dataset and Data Collection
- 4 Methodology
- 4.1 Texture Feature Extraction from Patches
- 4.2 Method for Supervised Learning
- 4.3 Methods for Semi-supervised Learning
- 4.4 Experimental Design
- 5 Results and Discussion
- 5.1 Summary and Conclusion
- References
- A Composite of Features for Learning-Based Coronary Artery Segmentation on Cardiac CT Angiography
- 1 Introduction
- 2 Composite Features
- 2.1 Relative Density
- 2.2 Local Shape Feature
- 2.3 Global Structure Feature
- 3 Supervised Learning-Based Segmentation
- 4 Experimental Results and Discussion
- 5 Conclusions and Future works
- References
- Ensemble Prostate Tumor Classification in H&E Whole Slide Imaging via Stain Normalization and Cell Density Estimation
- 1 Introduction
- 2 Methods
- 3 Results
- 4 Discussion
- 5 Conclusions
- References
- Computer-Assisted Diagnosis of Lung Cancer Using Quantitative Topology Features
- 1 Introduction
- 2 Methodology
- 2.1 Overview
- 2.2 Local Features
- 2.3 Topological Features
- 2.4 Summary of Features
- 3 Experiments
- 4 Conclusion
- References
- Inherent Structure-Guided Multi-view Learning for Alzheimer's Disease and Mild Cognitive Impairment Classification
- 1 Introduction
- 2 Proposed Method
- 2.1 Feature Extraction
- 2.2 Inherent Structure-Guided Sparse Feature Selection
- 2.3 Ensemble Classification
- 3 Experiments
- 3.1 Data and Experimental Settings
- 3.2 Results and Discussion
- 4 Conclusion
- References
- Nonlinear Feature Transformation and Deep Fusion for Alzheimer's Disease Staging Analysis
- 1 Introduction
- 2 TPS Metric Learning for Support Vector Machines (TML-SVM)
- 3 Neuroimage Data and Feature Extraction
- 4 Experiments and Results
- 4.1 Comparisons of Different Features
- 4.2 Comparisons of Different Feature Fusion Strategies
- 4.3 Comparisons of TML-SVM with Other Classifiers
- 5 Conclusions
- References
- Tumor Classification by Deep Polynomial Network and Multiple Kernel Learning on Small Ultrasound Image Dataset
- 1 Introduction
- 2 DPN-MKL Framework
- 2.1 Deep Polynomial Network Algorithm
- 2.2 Multiple Kernel Learning
- 3 Experiments and Results
- 3.1 Breast Ultrasound Image Dataset
- 3.2 Prostate Ultrasound Elastography Image Dataset
- 4 Conclusion
- Reference
- Multi-source Information Gain for Random Forest: An Application to CT Image Prediction from MRI Data
- 1 Introduction
- 2 Random Forest
- 2.1 Classic Random Forest
- 2.2 Structured Random Forest
- 3 Multi-source Information Gain
- 4 Experimental Analysis
- 4.1 Predicting CT Image from MR image
- 4.2 Integration to Auto-context Model
- 5 Discussion and Conclusion
- References
- Joint Learning of Multiple Longitudinal Prediction Models by Exploring Internal Relations
- 1 Introduction
- 2 Method
- 2.1 Notation and Problem Statement
- 2.2 Proposed Method
- 3 Experiments
- 4 Conclusions
- References
- Author Index
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