The Zebrafish: Disease Models and Chemical Screens
Academic Press
3rd Edition
Published on 9. September 2011
616 pages
978-0-12-381321-3 (ISBN)
Description
This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish.
- Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls
- This volume concentrates on Disease Models and Chemical Screens
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4th Edition
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11/2011
3rd Edition
Academic Press
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Content
Part I: Disease Models1. Germ Cell Tumors in Zebrafish2. Schwann Cell Myelination Mutants as Models of Multiple Sclerosis3. In Vivo Analysis of Zebrafish Adipogenesis4. Host-Microbe Interactions in the Zebrafish5. Hematopoietic Stem Cell Development and Blood Flow6. Zebrafish as a Model for Hemorrhagic Stroke7. Zebrafish Adaptive Immunity: Structure and Function of Physiologic Development and Malignant Transformation8. Zebrafish VHL Disease Model9. Muscle Diseases10. Basement Membrane Diseases11. Lymphangiogenesi12. Osteogenesis13. Zebrafish Assays of Ciliopathies14. Infectious Disease: Innate Immunity15. Tuberculosis16. Cancer17. Melanoma18. Pancreatic Cancer19. Rhabdomyosarcoma20. Transplantation in Zebrafish21. Modeling Human Disease by Gene Targeting 22. Fluorescent Imaging of Cancer23. Zebrafish as a Model for Fanconi's Anemia
Part II: Chemical Screens24. Chemical Screens for Potential Therapeutics25. Psychotropic Drug Discovery by Automated Behavioral Phenotyping26. Discovery and Use of Small Molecules for Probing Biological Processes
