Aliphatic and Polyhalogenated Carcinogens

General PlanPrefaceAcknowledgmentsPart III (Continued) Structure-Activity Relationships of Chemical Carcinogens. Effect of Reactivity, Molecular Geometry, and Metabolism on Carcinogenic Activity 5. Structure-Activity Relationships 5.2.Nonconjugated Organic Compounds Updating Notes Notes Added after Completion of Section 5.2.2.1 Notes Added after Completion of Section 5.2.2.2 Notes Added after Completion of Section 5.2.2.3 Notes Added after Completion of Section 5.2.2.4 Notes Added after Completion of Section 5.2.2.5 Notes Added after Completion of Section 5.2.2.7 Notes Added after Completion of Section 5.2.2.8 Notes Added after Completion of Section 5.2.2.9 Appendix I. Novel Types of Carcinogens Carbazole Anthanthrene Benzene Furylfuramide (Furfurylamide; AF-2) Niridazole 4-Nitropyridine N-Oxide Quinoline and Its Derivatives Quinoxaline 1,4-Dioxide Benzoyl Chloride and Other Acylating Agents Acetone Oxime (Acetoxime) Pronamide ZAMI 1305 Hycanthone 1,3-Butadiene Aniline and Azobenzene 4-Aminoazobenzene References to Appendix I Appendix II. Update to Vol. I: New Developments in Short-Term Tests for Carcinogenicity: Genetic Toxicology Testing Introduction Application of Genotoxicity Data to Human Health Effects Development of Genetic Toxicology Bioassays Application of Short-Term Bioassays to the Assessment of Human Cancer and Mutation Risk Concluding Remarks References to Appendix II Appendix III. Update to Vol. I: New Perspectives in Cancer Research Data Search: Modern Computer-Based Information Systems Introduction Computer Databases Useful for Cancer Research Automatic Selective Dissemination of Information Special Cancer Databases Other Databases of Interest for Cancer Research Special Publications That Provide Useful Information to Cancer Researchers Conclusion References to Appendix III Appendix IV. Update to Vol. IIA: Metabolic Activation by One-Electron and Two-Electron Oxidation in Aromatic Hydrocarbon Carcinogenesis Introduction Enzymology of One-Electron and Two-Electron Oxidation Two-Electron Oxidation or Monooxygenation of Aromatic Hydrocarbons One-Electron Oxidation of Aromatic Hydrocarbons: Radical Cations Discussion References to Appendix IVIndex