
Calcium
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Content
- Intro
- Cover page
- Publishing information
- Title page
- Copyright
- Contents
- Abstract
- Résumé
- Introduction
- References
- 1. Cell Cycles and Checkpoints
- The G¹ buildup: getting ready for chromosome replication
- A checkpoint to pass
- The S phase: replicating the chromosomes - a daunting task
- Mitosis and the birth of two new cells
- References
- 2. Calcium - A Cell Cycle Driver
- The cycle-driving Ca²+ signals: a quick preview
- Ca²+ and starting the cycle
- Ca²+ and the G¹-S transition
- Ca²+ in mitosis
- References
- 3. Calcium and Keratinocyte Diffpoptosis
- Stem cells and cell stacks
- Ca²+ gradient
- What triggers diffpoptosis?
- Ca²+ and diffpoptosis in the unreal world of the culture dish
- Ca²+ and diffpoptosis in the real world of the skin
- The first step: from basal cell to spinous cell
- From spinous cell to granular cell: CaRs and upward to the head of the Ca²+ gradient
- The final push to cornification and oblivion
- Summary
- Cancerous keratinocytes
- On the road to malignancy
- The end of the road: malignancy
- A farewell to the skin
- References
- 4. Calcium and Colon Cell Diffpoptosis
- Colon crypts, stem cells and a cellular escalator
- Ca²+ and the control of colon cell proliferation, differentiation, and apoptosis
- Integrins, ILK, catenins, and proliferation
- Ca²+, E-cadherins, APC, and diffpoptosis
- Colon cancer
- The beginning of the road to cancer - aberrant crypts, polyps, and a loss of Ca²+ control
- The end of the road - a lucky winning clone and colon carcinoma
- References
- 5. Calcium and Neurons
- Intercellular Ca²+ waves and signaling networks
- Presynaptic Ca²+ signaling and short-term plasticity
- Postsynaptic Ca²+ signaling and long-term plasticity
- Calcium and neurotransmitter release
- Ca²+ and neuronal cell death
- References
- 6. But What About Ca²+ and Plants?
- Ca²+ and blowing in the wind
- Calcium and light
- Cold, drought, and Ca²+
- Ca²+ as a driver of growth and proliferation
- Conclusion
- References
- 7. Summary
- Index
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