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The Biology of the Laboratory Rabbit is a compendium of papers that discusses the use of the rabbit as an experimental substrate in the scientific process. The collection describes normative biology, research utilization, and rabbit disease. These papers emphasize naturally occurring diseases which affect the value of the rabbit as a research tool. Some papers describe these effects and their impact for investigators engaged in laboratory experimental work on animal medicine. Other papers tackle the value of certain rabbit diseases as models of considerable interest in comparative medicine. Several papers discuss bacterial diseases, viral diseases, protozoal diseases, arthropod parasites, helminth parasites, neoplastic diseases, inherited diseases, nutritional diseases, metabolic, traumatic, mycotic, and miscellaneous diseases of the rabbit. One paper describes a number of diseases that man can acquire from domestic and laboratory rabbits. These include tularemia (which is endemic in wild rabbits and hares), plague (transmitted by fleas), listeriosis (rare in laboratory rabbit colonies), salmonellosis (from rabbit feces), and Pasteurella multocida (common in laboratory and domestic rabbits). The paper notes that laboratory and domestic rabbits are not a major health hazard. The compendium can benefit veterinarians, the medically-oriented investigator, the biologist, the medical and chemical researcher, and others whose work involve laboratory animal care.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-1-4832-7031-9 (9781483270319)
Schweitzer Classification
Chapter 1 Taxonomy and Genetics I. Taxonomy and Geographical Distribution of Rabbit Populations II. Origin and Domestication of the Rabbit II¿. Genetics of the Rabbit IV. Inbred Strains ReferencesChapter 2 Colony Husbandry I. Introduction II. Sexual Behavior and Breeding III. Feeds and Feeding Behavior IV. Commercial Herd Management V. Laboratory Management ReferencesChapter 3 The Anatomy, Physiology, and the Biochemistry of the Rabbit I. Introduction II. Anatomy-New Zealand White Rabbit III. Physiology IV. Biochemistry V. Hematology ReferencesChapter 4 Basic Biomethodology I. Introduction II. Handling and Restraint III. Sampling Techniques IV. Methods of Compound Administration V. Anesthesiology VI. Specialized Research Techniques VII. Euthanasia VIII. Necropsy Procedures ReferencesChapter 5 The Fetus in Experimental Teratology I. Introduction II. Summarized Cyclic and Embryological Phenomena III. Summarized Laboratory Techniques for Observation and Evaluation IV. Fetal Pathology and Anatomical Variation V. Teratological Investigation VI. Conclusions ReferencesChapter 6 Specialized Research Applications: I. Arteriosclerosis Research I. Introduction and Scope of the Review II. History of the Use of Rabbits in Arteriosclerosis III. Research IV. Naturally Occurring Arteriosclerosis of Rabbits V. Diet-Induced Atherosclerosis of Rabbits VI. Regression of Cholesterol-Induced Atherosclerosis of Rabbits ReferencesChapter 7 Specialized Research Applications: II. Serological Genetics I. The Blood Group Antigens II. The Transplantation Antigens ReferencesChapter 8 Gnotobiology I. Introduction II. The Caesarian Concept III. Hand Rearing IV. Intestinal Flora V. Sterility Testing VI. Gnotobiotic Isolators and their Maintenance VII. Microbiological Monitoring and Histological Evaluation VIII. Research Utilization ReferencesChapter 9 Bacterial Diseases I. Introduction II. Pasteurellosis III. Tularemia IV. Yersiniosis (Pseudotuberculosis) V. Necrobacillosis VI. Salmonellosis VII. Tyzzer's Disease VIII. Listeriosis IX. Tuberculosis X. Treponematosis XI. Staphylococcosis XII. Miscellaneous Bacterial Diseases ReferencesChapter 10 Viral Diseases I. Introduction II. DNA Virus Infections III. Diseases Caused by RNA Viruses IV. Diseases Possibly of Viral Origin ReferencesChapter 11 Protozoal Diseases I. General Introduction II. Sporozoa III. Toxoplasmida IV. Microsporida V. Flagellates and Amoebae VI. Organisms of Uncertain Classification ReferencesChapter 12 Arthropod Parasites I. Introduction II. The Principal Arthropod Groups ReferencesChapter 13 Helminth Parasites I. Introduction II. Natural Infections III. Experimental Infections IV. Conclusions ReferencesChapter 14 Neoplastic Diseases I. Introduction II. Neoplasms of Oryctolagus sp. III. Neoplasms of Sylvilagus sp. IV. Neoplasms of Lepus sp. V. Neoplasms Associated with Oncogenic Viruses VI. Transplantable Neoplasms Used as Model Systems ReferencesChapter 15 Inherited Diseases and Variations I. Introduction II. Conditions Controlled by Single (Mutant) Genes III. Familial or Polygenic Conditions IV. Sources of Rabbits with Inherited Diseases and Variations ReferencesChapter 16 Nutrition and Nutritional Diseases of the Rabbit I. Comparative Nutrition II. Vitamins III. Minerals IV. Summary ReferencesChapter 17 Metabolic, Traumatic, Mycotic, and Miscellaneous Diseases of Rabbits I. Introduction II. Pregnancy Toxemia III. Shock Disease IV. Pylorospasm V. Mucoid Enteropathy VI. Superficial Mycoses VII. Deep Mycoses VIII. Mastitis IX.