Statistical Methods in Drug Combination Studies
Published on 19. December 2014
240 pages
978-1-4822-1675-2 (ISBN)
Description
The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. Howeve
Reviews / Votes
"This book is a welcome addition to the literature and fills a needed niche since last book written on drug synergism was over 15 years ago . . . each chapter presents a different technique for solving common challenges in the development of drug combinations. . . Overall, this book serves as a good reference for both researchers in the field of statistics and drug combination development."~ Jessica L. Jaynes, California State University, Fullerton
"Investigating drug combinations is a steadily growing area in preclinical and clinical research.As usual, specific statistical methodology is needed to handle these kinds of trials. . . .the book is generallywell structured and the majority of sections actually builds up on and refers to each other. This book provides a good overview on and a good introduction to the topic of statistical methods for drug combination studies, especially regarding the preclinical part."
~ Tim Holland-Letz, German Cancer Research Center Heidelberg
More details
Series
Language
English
Place of publication
Philadelphia, PA
United States
Publishing group
Taylor & Francis Inc
Target group
College/higher education
Researchers involved in drug combination studies.
Illustrations
52 s/w Abbildungen, 27 s/w Tabellen
52 b/w images, 27 tables and 131 line eqations
File size
6,53 MB
ISBN-13
978-1-4822-1675-2 (9781482216752)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Wei Zhao | Harry Yang
Statistical Methods in Drug Combination Studies
Book
12/2020
1st Edition
Chapman & Hall/CRC
€59.41
Shipment within 15-20 days
Wei Zhao | Harry Yang
Statistical Methods in Drug Combination Studies
Book
12/2014
1st Edition
Chapman & Hall/CRC
€206.40
Article not available for order
Persons
Wei Zhao
Content
Drug Combination: Much Promise and Many Hurdles. Drug Combination Synergy. Drug Combination Design Strategies. Confidence Interval for Interaction Index. Two-Stage Response Surface Approaches to Modeling Drug Interaction. A Bayesian Industry Approach to Phase I Combination Trials in Oncology. Statistical Methodology for Evaluating Combination Therapy in Clinical Trials. Challenges and Opportunities in Analysis of Drug Combination Clinical Trial Data. Software and Tools to Analyze Drug Combination Data.
