
Organic Synthesis Highlights II
Description
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Part I describes new methods and reagents including asymmetric carbon-carbon bond formation with metallocenes and with enzymes, via temporary silicon connections, and by means of carbohydrate complexes. Part II describes landmarks in the synthesis of natural products and surveys synthetic strategies to different classes of natural products.
The forty essays in this volume bear witness to the creativity and talent which have led to the recent advances in the field. Both advanced students and researchers active in the field will welcome this as a source of ideas and inspiration.
Reviews / Votes
From a review of Volume I:'The essays are particularly nice starting ponts for planning one or a series of lectures for an advanced synthesis course ... This [book] is entertaining to read and it is packed with references.'
J. Am. Chem. Soc.
From reviews of Volume II:
'Organic Synthesis Highlights II is a collection of 40 articles which provide an overview of some of the most recent and important accomplishments in organic synthesis ... Organic Syntheis Highlights II is well-organized, and each of the topics are well-referenced and timely. The diverse nature of the topics included in this text make it a very valuable reference to anyone interested in organic chemistry.'
Journal of Natural Products
'The treatment is very suitable for advanced, graduate students, as well as those with experience beyond the Ph. D. level, and the book is clearly an excellent starting point for an introductory overview of the subjects it covers ... Any synthetic organic chemist in the early stages of a research career will find this a helpful - and enjoyable - source of information and an excellent overview of the state of modern organic synthesis. The present book is the second of ist type from VCH, and I hope that a third volume will appear in due course.'
J. Am. Chem. Soc.
'Organic Synthesis Highlights II will obviously be of great value for post-graduate students and for everyone interested in modern synthetic methods. It is also eminently suitable as a source for preparing seminars and colloquia for advanced undergraduate students. From the standpoint of students especially, it would of course be helpful if this excellent book could also be published in a cheaper paperback edition.'
Angewandte Chemie, International Edition
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Person
Herbert Waldmann (b 1957) received his PhD in 1985 from the University of Mainz (Germany) with H. Kunz. After postdoctoral studies (1985-1986, Harvard University, George Whitesides) and habilitation (1991, University of Mainz) he was appointed associate professor at the University of Bonn in 1991. In 1993 he moved to the University of Karlsruhe as Full Professor of Organic Chemistry. In 1999 he was appointed Director at the Max Planck Institute of Molecular Physiology in Dortmund, where he is heading the Department of Chemical Biology. He also holds a Professorship in Biochemistry at the University of Dortmund. Herbert Waldmann has been the recipient of the Friedrich Weygand Award for the advancement of peptide chemistry, of the Carl Duisberg Award of the Gesellschaft Deutscher Chemiker, the Otto-Bayer-Award and the Steinhofer Award of the Steinhofer Foundation.
His current research interests include bioorganic chemistry and natural product synthesis as well as biocatalysis, stereoselective synthesis and combinatorial chemistry.
Content
New Methods and Reagents for Organic Synthesis/ Enantioselective Deprotonation and Protonation/ Carbohydrate Complexes in Enantioselective Carbon-Carbon Bond Formation/ Asymmetric Aza-Diels-Alder Reactions/ Iron eta5-Complexes in Organic Synthesis/ Rhodium-Catalyzed Carbenoid Cyclizations/ Enzymatic Synthesis of O-Glycosides/ Electrophilic Cyclizations in the Synthesis of Heterocycles/ Polycyclization as a Strategy in the Synthesis of Complex Alkaloids/ Domino Reactions/ Group Selective Reactions/ Hypervalent Iodine Reagents/ Taxanes: An Unusual Class of Natural Products/ CC-1065: One of the Most Powerful Anti-Tumor Compounds/ Synthesis of Calicheamicin/ Total Synthesis of Rapamycin
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