Vitamins and Hormones

Name: Vitamins and Hormones
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Published on 1. January 1969

791 pages

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Front Cover
Vitamins and Hormones, Volume 26
Copyright Page
Contents
Contributors to Volume 26
Preface
Chapter 1. Some Aspects of Vitamin A Metabolism
I. Introduction
II. Nomenclature and Chemistry
III. Physical Properties and Analytical Procedures
IV. Overall Metabolism
V. Enzymatic Transformation
VI. Interaction of Vitamin A with Macromolecules
VII. Concluding Remarks
References
Chapter 2. The Hormonal Regulation of Glycogen Metabolism in Muscle
I. Introduction
II. The State of Glycogen in Muscle
III. Dynamics of Glycogen as an Energy Source in Muscle Metabolism
IV. Enzymes of Glycogen Metabolism in Muscle
V. Control by Epinephrine
VI. Control of Glycogen Metabolism in Muscle by Thyroid Hormones
VII. Control by Insulin
VIII. Control by Other Hormones
IX. Concluding Speculative Remarks
References
Chapter 3. The Mechanism of Action of Adrenocorticotropic Hormone
I. Introduction
II. Relationship of the Structure of ACTH to Its Function
III. Pathway of Adrenal Cortical Biosynthesis
IV. Adenosine 3'.5'-Phosphate (Cyclic-AMP) and Steroidogenesis
V. Hypothetical Models of ACTH Action in Stimulating Steroidogenesis
VI. ACTH and Adrenal Growth
References
Chapter 4. The Influence of Estrogens, Progestins, and Pregnancy on the Liver
I. Introduction
II. Anatomic Alterations
III. Nucleic Acid and Protein Metabolism
IV. Carbohydrate Metabolism
V. Lipid Metabolism
VI. Metabolism of Drugs and Cholephilic Substances
VII. Concluding Remarks
References
Chapter 5. Prolactin
I. Introduction
II. Animal Prolactin
III. Human Prolactin
References
Chapter 6. Effects and Metabolism of Hormones in Normal and Neoplastic Prostate Tissue
I. Introduction
II. Influence of Hormones on Prostatic Structure and Function
III. Catabolism of Sex Hormones in the Prostate
IV. Hormonal Influences on the Neoplastic Prostate
V. Concluding Remarks
References
Chapter 7. Preliminary Characterization of Some Ectopic Hormones
I. General Introduction
II. Ectopic Adrenocorticotropic Hormone (ACTH)
III. Ectopic Melanocyte-Stimulating Hormone (MSH)
IV. Ectopic Parathyroid Hormone
V. Ectopic Antidiuretic Hormone (ADH)
VI. Ectopic Gastrin
VII. Ectopic Thyrotropin-like Material
VIII. Ectopic Gonadotropins
IX. Ectopic Erythropoietin
X. Conclusions
References
Chapter 8. International Symposium on Vitamin-Related Anemias in Honor of Professor
Introductory Remarks
Text
References
Chapter 9. Historical Survey
Text
Summary and Prospects
References
Chapter 10. Hemoglobin Synthesis and Differentiation of Erythroid Cells
I. Introduction
II. Embryological Aspects of Erythropoiesis
III. Hemoglobins
IV. Summary
References
Chapter 11. Mechanism and Control of Pyrrole Synthesis
I. Introduction
II. Mechanism of Porphobilinogen Synthesis
III. Discussion
References
Chapter 12. Folic Acid Coenzymes in the Biosynthesis of Purines and Pyrimidines
I. Introduction
II. Biosynthesis of Purines
III. Biosynthesis of Pyrimidines
IV. Conclusion
References
Chapter 13. Metabolic Role of Vitamin B12
I. Introduction
II. Cleavage and Synthesis of the Carbon-to-Cobalt Bond
III. Enzyme-Catalyzed Reactions Requiring 5'-Deoxyadenosyl Cobamides
IV. Mechanism of the 5'-Deoxyadenosyl-B12-Dependent Reactions
V. Methyltransferase Reactions
VI. Role of Vitamin B12 in Animal Metabolism
References
Chapter 14. Deoxyribonucleotide Synthesis and the Role of Vitamin B12 in Erythropoiesis
I. Introduction
II. Deoxyribonucleotide Synthesis in Bacteria
III. Deoxyribonucleotide Synthesis in Animal Cells
IV. Effects of Vitamin B12 Deficiency on Erythropoiesis
V. Concluding Remarks
References
Chapter 15. Experimental Anemias in Animals Resulting from Folic Acid and Vitamin B12 Deficiencies
I. Introduction
II. Monkeys
III. Swine
IV. Rats
V. Chicks
VI. Guinea Pigs
VII. Ruminants
References
Chapter 16. Blood Changes in Experimental Primates Fed Purified Diets: Pyridoxine and Riboflavin Deficiency
I. Purified Diets for Experimental Primates
II. Methods
III. Results
IV. Discussion
References
Chapter 17. Lipids, a-Tocopherol, and Erythrocyte Hemolysis
I. Introduction
II. Methods
III. Results
IV. Discussion
References
Chapter 18. Experimental Anemia in Primates Due to Vitamin E Deficiency
I. Introduction
II. Adequacy of the Purified, Vitamin E-Supplemented Diets
III. The Course of Vitamin E Deficiency in the Monkey
IV. The Anemia of Vitamin E Deficiency
V. Response of Anemic. Vitamin E-Deficient Monkeys to Therapy
VI. Comments on the Function of Vitamin E
.VII. Summary
References
Chapter 19. Ferrokinetics and Hemoglobin Synthesis in Man
I. Introduction
II. Pathways of Iron Exchange
III. Quantitative Aspects of Internal Iron Exchange
IV. Normal Ferrokinetics
V. Hemoglobin Synthesis and Iron Deficiency Anemia
VI. Summary
References
Chapter 20. Folic Acid Deficiency in Man
I. Introduction
II. Etiology
III. Sequence of Biochemical and Hematological Events as Deficiency Develops
IV. Blood and Nerve Damage in Folate Deficiency
V. Laboratory Diagnosis
VI. Treatment
References
Chapter 21. Discussion of Herbert's Paper
Text
References
Chapter 22. Pernicious Anemia and Its Variants
I. Introduction
II. Lack of Intrinsic Factor
III. Lack of Intrinsic Factor Caused by Degenerative Gastric Atrophy and Chronic Gastritis
IV. Vitamin B12 Deficiency from Causes Other Than Lack of Intrinsic Factor
V. Conclusion
References
Chapter 23. Discussion of Thedering's Paper
Text
References
Chapter 24. Pyridoxine-Responsive Anemias in Man
I. Introduction
II. "Classic Form''
III. Variations from the ''Classic Form"
IV. Recent Observations Reported in the Literature (1964-1967)
V. Case Presentations
References
Chapter 25. Discussion of Horrigan and Harris' Paper
Text
References
Chapter 26. Hematological Changes in Protein Calorie Malnutrition
I. Introduction
II. Clinical Description of the Anemia of Protein Calorie Malnutrition
III. Etiology of the Anemia of Protein Calorie Malnutrition
IV. Own Investigations
V. Discussion
VI. Concluding Remarks
References
Chapter 27. Discussion of Viteri ef al.'s Paper
Text
Chapter 28. Erythropoietin and Erythropoiesis
I. Introduction
II. Evidence for the Existence of a Humoral Stimulator of Erythropoiesis
III. Methods for Demonstrating Erythropoietin
IV. Chemistry
V. Erythropoietin and the Physiology of Red Cell Production
VI. Clinical Aspects
References
Chapter 29. The Anemia of Scurvy
I. The Hematology of Scurvy
II. Hemolysis and the Anemia of Scurvy
III. The Possibility of Deficiencies Other Than Vitamin C in Scurvy
IV. The Hematological Effect of Therapy with Ascorbic Acid
V. Conclusions
References
Chapter 30. Comparison between Erythroid Aplasia in Marasmus and Kwashiorkor and the Experimentally Induced Erythroid Aplasia in Baboons by Riboflavin Deficiency
I. Introduction
II. Etiology of Erythroid Aplasia
III. Materials and Methods
IV. Clinical Findings
V. Laboratory Findings
VI. Treatment of Erythroid Aplasia
VII. Discussion
VIII. Summary
References
Chapter 31. Discussion of Foy and Kondi's Paper
Text
References
Chapter 32. Tocopherol-Responsive Anemias in Man
I. Introduction
II. Some Relevant Nutritional Concepts
III. Experimental Production of Anemia in Tocopherol Deficiency
IV. Tocopherol-Responsive Anemia in Malnourished Infants
V. Tocopherol-Related Factors
VI. Hemopoietic Effect of Tocopherol in Adult Men
VII. Other Tocopherol-Responsive Anemias in Man
VIII. Summary and Conclusions
References
Chapter 33. Discussion of Darby's Paper
Text
References
Chapter 34. An Epidemiologic Approach to the Causes and Control of the Nutritional Anemias
I. Introduction
II. Host Factors in the Etiology of Anemias
III. Agent Factors
IV. Environmental Factors in the Etiology of Anemias
V. Conclusions and Recommendations
References
Chapter 35. Discussion of Scrimshaw's Paper
Text
References
Author Index
Subject Index
Cumulative Topical Index for Volumes 21-25

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