Vitamins and Hormones

Name: Vitamins and Hormones
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Academic Press

Published on 1. January 1967

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978-0-08-086621-5 (ISBN)

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Front Cover
Vitamins and Hormones: Advances in Research and Applications
Copyright Page
Contents
Contributors to Volume 24
Preface
Chapter 1. Insulin and the Regulation of Hepatic Biosynthetic Activity
I. Introduction
II. Glycogen Synthesis
III. Glucose Phosphorylation and Liver Glucokinase
IV. Other Enzymes of Carbohydrate Metabolism
V. Lipid Biosynthesis
VI. Nucleic Acid and Protein Biosynthesis
VII. Some Speculations on Mechanism
VIII. Conclusions
References
Chapter 2. Some Observations on the Assay of Anterior Pituitary Hormones
I. Introduction
II. Follicle-Stimulating Hormonc and Luteinizing Hormone
III. Prolactin
IV. Growth Hormone
V. Adrenocorticotropic Hormone
VI. Thyroid-Stimulating Hormone
VII. Discussion
VIII. Conclusions
References
Chapter 3. Contributions of the Intestinal Microflora to the Nutrition of the Host
I. Introduction
II. "Natural" Dietary Factors
III. Antibacterial Substances
IV. Gnotobiotic Rearing and Coprophagy
V. Summary and Conclusions
References
Chapter 4. The Detection and Measurement of Thyrotropic Substances in Health and Disease
I. General Introduction
II. Interrelationship between the Pituitary and Thyroid Glands
III. Standards of Reference
IV. Methods of Extraction and Purification of TSH
V. Parameters Used in the Detection and Measurement of TSH
VI. Measurements of TSH in Health and Disease
VII. The Long-Acting Thyroid Stimulator
VIII. General Conclusions
References
Chapter 5. Alarm Substances and Alarm Behavior in Social Insects
I. Introduction
II. Alarm in the Honey Bee
III. Comparative Investigations of Alarm in Social Hymenoptera
IV. Alarm in Termites
V. The Evolution of Chemical Alarm as Exemplified in Hymenoptera
VI. Concluding Remarks
References
Chapter 6. International Symposium on Recent Advances in Research on Vitamins K and Related Quinones (Vitamins K, Ubiquinones or Coenzymes Q, Plastoquinones) in Honor of Professor Henrik Dam
Introductory Remarks
Chapter 7. Historical Survey and Introduction
I. The Early Studies in the Vitamin K Field
II. Isolation and Chemical Identification of Vitamins K
III. Vitamin K in Human Pathology
IV. Studies on the Mode of Action of Vitamin K in the Animal Body
V. Vitamins K in Microorganisms
VI. Vitamin K and Related Quinones in Photosynthesis
Plastoquinones
VII. Ubiquinones and Ubichromenols
VIII. Conclusions
References
Chapter 8. Occurrence of Vitamins K and Related Quinones
I. Introduction
II. Vitamins K and Related Compounds
III. Ubiquinones
IV. Plastoquinones
V. Tocopherolquinones
VI. Conclusions
References
Chapter 9. Syntheses of Vitamins K and Related Compounds with Special Reference to Labeling
I. Introduction
II. Syntheses of Isoprenoid Chains
III. Syntheses of Ring Components
IV. Syntheses of Isoprenoid Quinones
V. Transformations and Syntheses of Metabolites
VI. Labeled Compounds
VII. Concluding Remarks
References
Chapter 10. Physicochemical Properties and Methods of Analysis of Phylloquinones, Menaquinones, Ubiquinones, Plastoquinones, Menadione, and Related Compounds
I. Physicochemical Properties
II. Separation and Assay Methods
References
Chapter 11. Session 1: Summary and Prospects
Comments on Session 1
References
Chapter 12. Phosphorylation of Derivatives of the Vitamin K Group
I. Introduction
II. The Possible Role of Quinones in Oxidative Phosphorylation
III. Isomerization of Naphthoquinones to Methylene Quinone Chromanes
IV. Chemical Synthesis of Phosphate Derivatives
V. Chemical Properties of Chromanyl Phosphates
VI. Biological Experiments with Phosphorylated Derivatives of Vitamin K and Ubiquinone
VII. Conclusions
References
Chapter 13. The Chemistry of Ubiquinone
I. Introduction
II. Mass Spectrometry of the Ubiquinones
III. Biosynthesis of Ubiquinone
IV. Summary
References
Chapter 14. Mode of Action of Vitamins K in Animals
Text
References
Chapter 15. Mode of Action of Vitamin K in Microorganisms
I. Introduction
II. Quinones as Members of the Respiratory Chain
III. Quinone-Bypass Reactions
IV. Phosphate-Dependent Protonation of a Naphthoquinone
V. Enzymatically Formed Quinol Derivative of Vitamin K1
VI. Malate-Vitamin K Reductase
VII. Summary
References
Chapter 16. Mode of Action of Ubiquinones (Coenzymes Q) in Electron Transport Systems
I. Introduction
II. Distribution of Ubiquinones
III. Reactions of Endogenous Ubiquinone
IV. The Possible Role of Ubiquinone in Oxidative Phosphorylation
V. Extraction-Reactivation Experiments
VI. Activation of Electron Transport by Ubiquinone Homologs
VII. Ubiquinone in Bacterial Electron Transfer
VIII. Ubiquinone in Photosynthetic Electron Transport
IX. Conclusions
References
Chapter 17. Function of Quinones in Photosynthesis
I. Chloroplast Quinones
II. Photosynthetic Electron Transport
III. Function of Plastoquinone A (45)
IV. Quinone Distribution in Fragmented Chloroplasts
V. Quinones in Photophosphorylation
VI. Conclusion
References
Chapter 18. Session 2: Summary and Prospects
I. Comments on Session 2
II. The Role of Ubiquinones in Biology and Medicine
References
Chapter 19. Biosynthesis of Ubiquinones and Vitamins K in Microorganisms
I. Introduction
II. Precursors of the Benzoquinone Ring of Ubiquinone
III. The Origin of the Ring-Methyl Group
IV. Rhodoquinone
V. The Biosynthesis of Vitamins K
VI. Intermediate Steps in the Conversion of p-Hydroxybenzoic Acid to Ubiquinone
VII. Cell-Free Systems for Ubiquinone Biosynthesis
References
Chapter 20. Biosynthesis of Ubiquinones in Animals
I. Introduction
II. Biosynthesis of Coenzyme Q in Vivo
III. Biosynthesis of Coenzyme Q in Vitro
IV. Intermediate Metabolites in Coenzyme Q Biosynthesis
V. Ubiquinone-Ubichromenol Interconversion
VI. Summary
References
Chapter 21. Absorption, Distribution, Storage, and Metabolites of Vitamins K and Related Quinones
I. Introduction
II. Experimental Methods
III. Absorption, Retention, and Distribution
IV. Metabolism
V. Summary
References
Chapter 22. Interrelationships between Ubiquinones and Vitamins and Hormones
I. Introduction
II. Dietary Effects
III. Hormonal Effects
IV. Summary
References
Chapter 23. Session 3: Summary and Prospects
I. Comments on Session 3
II. Prospects and Historical Perspective
Chapter 24. Biological Activity of the Various Vitamin K Forms
I. A Survey of the Development of the Various Forms of Vitamin K
II. Biological Activity of the Various Forms of Vitamin K
III. Biological Activity of Vitamin K in the Presence of Anticoagulant Stress
IV. Activity of Vitamin K in Vitro Systems
V. Summation, with Special Reference to Possible Metabolic Pathways
References
Chapter 25. Antagonists of Vitamin K
I. The Nature of Vitamin K Activity
II. Anticoagulant Activity of Coumarins and Indandiones
III. The Agonist and Antagonist Activity of Quinones
IV. Sulfonamides, Antibiotics, and Other Compounds
V. Effect of Antagonists in Microorganisms and Tissue Cultures
VI. Dietary Vitamin A and Some Other Factors Influencing the Absorption and Utilization of Vitamin K
VII. Quantitative Aspects of Antagonism and Its Prevention by Vitamin K Analogs in Relation to the Biological Role of Vitamin K
References
Chapter 26. Vitamin K in Animal Nutrition
I. Introduction
II. Deficiency Diseases
III. Requirements
IV. Hypervitaminosis K
V. Antivitamins, Inhibitors, and Metabolic Interrelationships
VI. Need for Vitamin K Supplementation of Practical Poultry Diets
References
Chapter 27. Vitamin K in Medical Practice: Pediatrics
I. Introduction
II. Coagulation in the Newborn
III. Bleeding Disorders of the Newborn
IV. Vitamin K in Prophylaxis and Treatment of Hemorrhagic Manifestations
V. Toxicity of Vitamin K Preparations
VI. Recommendations for the Use of Vitamin K in the Newborn
VII. Summary
References
Chapter 28. Vitamin K in Medical Practice : Adults
I. Vitamin K and Blood Coagulation
II. Deficiency of Vitamin K-Dependent Clotting Factors
III. Symptomatology and Diagnosis of Vitamin K Deficiency
IV. Therapy of Vitamin K Deficiency
V. Vitamin K as a Differential Diagnostic Tool
VI. Pharmacological Effects of Vitamin K
VII. Side Effects of Vitamin K
References
Chapter 29. Session 4 : Summary and Prospects
I. Biological Activity of Vitamin K
II. Nature of the Activity of Vitamin K and Vitamin K Antagonists
III. The Role of Vitamins K in the Animal
IV. Neonatal Bleeding Disorders and Vitamin K
V. Vitamin K Deficiency and Treatment in Adults
VI. Concluding Remarks
References
Author Index
Subject Index

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Vitamins and Hormones

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