Frontiers in Catecholamine Research
Proceedings of the Third International Catecholamine Symposium Held at the University of Strasbourg, Strasbourg, France May 20-25, 1973
Published on 18. May 2014
1236 pages
978-1-4831-5586-9 (ISBN)
Description
Frontiers in Catecholamine Research is a collection of papers presented at the Third International Catecholamine Symposium, held at the University of Strasbourg, Strasbourg, France, on May 20-25, 1973. This book is organized into nine parts encompassing 205 chapters. The text begins with a discussion on clinically and experimentally used drugs that have been developed or whose mechanism of action has been clarified through monoamine research. Parts II and III deal with enzymes related to catecholamine studies, their properties, regulation, genetics, mechanism of action, and localization. Parts IV and V examine the concepts of synaptic dynamics of brain regulators and the isolation, characterization, methods of analysis, and mechanism of action of catecholamines. Part VI focuses on the complexities that surround the extrapolation of catecholamine function into the realms of electrophysiology and behavior. Part VII discusses the metabolism, behavioral, neurological, and physiological effects of amphetamine and other drugs of abuse. The concluding parts describe the role of catecholamine and its metabolism in neurologic diseases, such as schizophrenia.
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Foreword Historical Acknowledgments ParticipantsAbbreviationsI. Keynote Address The Impact of Monoamine Research on Drug DevelopmentII. Enzymes Two Mechanisms of Catecholamine storage in Adrenal Chromaffin Granules Properties of Tyrosine Hydroxylase Cofactors of Tyrosine Hydroxylase Characterization of dopa decarboxylase Characterization, Localization and Regulation of Catecholamine Synthesizing Enzymes Immunological Localisation of Dopamine-ß-Hydroxylase on the Chromaffin Granule Membrane New Inhibitors of Microbial Origin for Dopamine-ß-Hydroxylase Picolinic Acid Derivatives as Inhibitors of Dopamine ß-Hydroxylase In Vivo; their Effects on Blood Pressure and Stress Ulcer The Innervation of Cerebral Blood Vessels by Central Noradrenergic Neurons Comparative Studies on Bovine and Guinea Pig Tyrosine Hydroxylase Regulation of Phenylethanolamine N-Methyltransferase Catechol-O-Methyltransferase The cellular Localization and Physiological Role of Catechol-O-Methyltransferase in the Body Immunological Characterization of Catechol-O-Methyltransferase New Concepts on the N-Methylation Reactions of Biogenic Amines in Adrenal Medulla and Brain Ring Dehydroxylation of N-Methylation of Noradrenaline and Dopamine in the Intact Rat Brain Degradation of the Transmitter Amines by Specific Types of Monoamine Oxidases The Importance of the 'Hydroxylamine Metabolic Route' in Pharmacology, Toxicology and Pharmacokinetics Some Characteristics of Rat Liver Mitochrondrial Monoamine Oxidases The Nature of the Electrophoretically Separable Forms of Monoamine Oxidase Transformation of Monoamine Oxidases and Deamination of Fattyaromatic Monoamines On the Mechanism of Inhibition of Monoamine Oxidase Selective Localization of Monoamine oxidase Forms in Rat Mesenteric Artery Oxidative-Reductive Pathways for Metabolism of Biogenic Aldehydes Sulfate Conjugates in the Brain Reporter's Notes First Session Second SessionIII. Regulation Trans-synaptic Regulation of Tyrosine Hydroxylase Modulation of Adrenal Tyrosine Hydroxylase Induction by Serotonin Nerve Function Role of Catecholamines in Induction of Adrenal Tyrosine Hydroxylase Dopamine-ß-Hydroxylase and the Regulation of Catecholamine Biosynthesis Retrograde Axonal Transport of Dopamine-ß-Hydroxylase Growth and Development of a Sympathetic Ganglion In Vivo Studies on the Mechanism of Regulation of Tyrosine Hydroxylase Activity during Nerve Stimulation Transsynaptic and Humoral Regulation of Adrenal Catecholamine Synthesis in Stress Transsynaptic Regulation of Tyrosine Hydroxylasein Adrenal Medulla: Possible Role of Cyclic Nucleotides Comment-Cholinergic Regulation of Tyrosine Hydroxylase Sympathetic Ganglia in Culture Lack of Relationship between Noradrenaline Content and Tyrosine Hydroxylase Activity in Cultured Sympathetic Ganglia Induction of Tyrosine Hydroxylase in Superior Cervical Ganglion by Cold Exposure: Effects of Decentralization and Mecamylamine Regulation of Catechol Synthesis in an Adrenergic Clone of Mouse Neuroblastoma Development of the Central Catecholaminergic Neurons of the Rat Interaction between the Nerve Growth Factor (NGF) and Adrenergic Blocking Agents in Sympathetic Neurons Neuroblastoma Cells as a Tool for Neuronal Molecular Biology Reporter's NotesIV.
