Macrophage Regulation of Immunity

ParticipantsPrefaceAcknowledgmentsSection 1. Antigen Handling and Presentation-Ir Gene Control I Determinant Selection and Macrophage-Mediated Ir Gene Function The Role of Macrophages in Determining the Balance of Regulatory T Cells Specific for L-Glutamic Acid60-L-Alanine30-L-Tyrosine10(GAT) Restrictions on Macrophage-Lymphoid Cell Interactions in Secondary Antibody Responses to Fowl Gamma Globulin in Vitro Macrophage Regulation of Guinea Pig T Lymphocyte Responses to Human Fibrinopeptide B1 The Role of Antigenic Determinants in Macrophage-T Lymphocyte Interaction T Cell-Macrophage Interaction in Infection to the Intracellular Pathogen Listeria monocytogenes Attempts at Determinant-Specific Antibody Blockade of Macrophage PresentationSection 2. Antigen Handling and Presentation-Ir Gene Control II H-2-Restricted Presentation of Antigen to T Helper Cells in Vivo Expression of/-Region Genes during Helper T Cell Maturation of Induction The Role of Antigen-Presenting Cells in Effector Helper T Cell Action Interactions of Macrophages and T Cells in the Development of Antibody and Proliferative Responses Major Histocompatibility Complex Restricted Helper T Cell Recognition of Accessory Cells but Not B CellsSection 3. Ir Gene Control-Physical Interactions between Macrophages and Lymphocytes Genetic Control of T Cell-Macrophage Interaction in Helper Cell Induction in Vitro Macrophage-T Cell Interaction in a Primary Antibody Response Dependent on an I-J Subregion Macrophage Determinant Antigen Specific Physical Interaction between Macrophages and T Lymphocytes Mechanisms Underlying the Interaction of Guinea Pig T Lymphocytes with Antigen-Pulsed Macrophages Quantitation of Genetically Restricted T Cell-Macrophage BindingSection 4. Antigen-Presenting Cells Characterization of the Accessory Cells Required in T Lymphocyte Dependent Antigen-Specific Immune Responses Antigen-Presenting Lymphoid Tumors in the Murine T Lymphocyte Proliferative Response to DNP-Ovalbumin and Poly(Glu55Lys36Phe9) Langerhans Cell-Lymphocyte Interactions Dendritic Cells, an Important New Cell Type in MHC-Linked Functions Macrophage Heterogeneity: Membrane Markers and Properties of Macrophage Subpopulations Macrophage Heterogeneity in the Stimulation of T Cell Proliferation Isolation of Guinea Pig Kupffer Cells and in Vitro Analysis of Their Capacity to Interact with T Lymphocytes for the Induction of Immune ResponsesSection 5. Factors Affecting Lymphocyte-Macrophage Interactions Secretion of Arachidonic Acid Oxygenation Products by Mononuclear Phagocytes: Their Possible Significance as Modulators of Lymphocyte Function Role of Macrophages in the Regulation of Thymocyte Proliferation and Differentiation Role of Cytokine- and Endotoxin-Induced Monokines in Lymphocyte Proliferation, Differentiation, and Immunoglobulin Production The Use of Synthetic Compounds to Replace the Macrophage Requirement for T Lymphocyte Activation Comparison of the Effects of Macrophages, 2-Mercaptoethanol, and Levamisole on Lymphoid Cells Information Transfer between T Cell Sets: The Macrophage Is the MessageSection 6. Regulation of Macrophage Function Regulation of Intracellular Killing by Extracellular Stimulation of the Monocyte Membrane The Use of Cloned Mononuclear Phagocytes to Study Immunoregulation Control of Macrophage-T Cell Interactions Adjuvant Activation of Macrophage Functions Evidence That Monocyte-Mediated Cellular Recognition Phenomena Are Mediated by Receptors with Specificity for Simple OligosaccharidesAuthor IndexSubject Index