Prostate Cancer
Biochemistry, Molecular Biology and Genetics
1st Edition
Published on 9. May 2013
XII, 522 pages
978-1-4614-6828-8 (ISBN)
Description
Prostate Cancer
provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. It includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer.
More details
Series
Language
English
Place of publication
New York
United States
Publishing group
Springer US
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
XII, 522 p.
File size
11,00 MB
ISBN-13
978-1-4614-6828-8 (9781461468288)
DOI
10.1007/978-1-4614-6828-8
Schweitzer Classification
Other editions
Additional editions
Book
06/2015
Springer
€213.99
Shipment within 15-20 days
Book
05/2013
Springer
€213.99
Shipment within 15-20 days
Content
Preface.- Section 1: Cell Biology.- Stem Cells in the Normal and Malignant Prostate.- Role of Reactive Stroma in Prostate Cancer.- The Role of Cholesterol in Prostate Cancer.- Section 2: Genetics: PTEN in Prostate Cancer.- ETS fusion genes in prostate cancer.- Section 3: Cell Signaling.- Signaling Mechanisms of Vav3, a Guanine Nucleotide Exchange Factor and Androgen Receptor Coactivator, in Physiology and Prostate Cancer Progression.- Transforming Growth Factor-beta (TGF-b) in Prostate Cancer.- The p38 MAPK Pathway in Prostate Cancer.- NF-kappaB2/p52 in Prostate Cancer.- The functional role of DAB2IP, a homeostatic factor, in prostate cancer.- Tyrosine Kinases in Prostate Cancer.- Human prostatic acid phosphatase in prostate carcinogenesis.- Section 4: Hormonal.- Truncated Androgen Receptor Splice Variants in Prostate Cancer.- Biology and Clinical Relevance of Estrogen Receptors in Prostate Cancer.- Vitamin D and Prostate Cancer.- HDAC6 regulation of androgen signaling in prostate cancer.- Beyond the cell cycle: Implications of D-type cyclin deregulation in Pca.- Section 5: Cell Death.- Role of Par- in Prostate Cancer.- Autophagy and Prostate Cancer Therapeutics.- Index.
