Textbook of Drug Design and Discovery
4th Edition
Published on 7. October 2009
476 pages
978-1-4398-8240-5 (ISBN)
Description
The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight into lead structures an
Reviews / Votes
"... figures are relevant and helpful in explaining concepts in the text. The level of detail in the contents of the book makes it especially suitable for academics and advanced students of medicinal chemistry, but may also be of interest to molecular pharmacologists. biochemists, and others of related disciplines."-Chromatographia "... figures are relevant and helpful in explaining concepts in the text. The level of detail in the contents of the book makes it especially suitable for academics and advanced students of medicinal chemistry, but may also be of interest to molecular pharmacologists. biochemists, and others of related disciplines."
-Chromatographia
More details
Edition
4th edition
Language
English
Place of publication
Baton Rouge
United States
Publishing group
Taylor & Francis Inc
Target group
College/higher education
Edition type
New edition
File size
17,39 MB
ISBN-13
978-1-4398-8240-5 (9781439882405)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Kristian Stromgaard | Povl Krogsgaard-Larsen | Ulf Madsen
Textbook of Drug Design and Discovery, Fourth Edition
Book
10/2009
4th Edition
CRC Press
€104.17
Article exhausted; check for reprint
Persons
Povl Krogsgaard-Larsen is a professor of medicinal chemistry in the Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, at the University of Copenhagen. Kristian Stromgaard is a professor of chemical biology in the Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, at the University of Copenhagen. Ulf Madsen is currently an associate dean in the Faculty of Pharmaceutical Sciences at the University of Copenhagen.
Content
Introduction to Drug Design and Discovery. Molecular Recognition in Ligand-Protein Binding. Biostructure-Based Drug Design. Ligand-Based Drug Design. Chemical Biology. Stereochemistry in Drug Design. Natural Products in Drug Discovery. Imaging in Drug Discovery and Development. Peptides and Peptidomimetics. Prodrugs: Design and Development. Metals in Medicine: Inorganic Medicinal Chemistry. Enzyme Inhibitors: Biostructure-Based and Mechanism-Based Designs. Receptors: Structure, Function, and Pharmacology. Ion Channels: Structure and Function. Neurotransmitter Transporters: Structure and Function. GABA and Glutamic Acid Receptor Ligands. Acetylcholine. Histamine Receptors. Dopamine and Serotonin. Opioid and Cannabinoid Receptors. Hypnotics. Neglected Diseases. Immunomodulating Agents. Anticancer Agents. Antiviral Drugs. Antibiotics. Index.
