
Current Topics in Membranes and Transport
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Content
- Front Cover
- Molecular Neurobiology: Endocrine Approaches
- Copyright Page
- Contents
- Preface
- Yale Membrane Transport Processes Volumes
- PART I: PEPTIDE ACTION
- Chapter 1. Peptides and Slow Synaptic Potentials
- I. Introduction
- II. Bullfrog Sympathetic Ganglia
- III. Other Slow Synaptic Actions
- IV. Conclusions
- References
- Chapter 2. Molecular Mechanisms of Neurite Formation Stimulated by Insulin-Like Factors and Nerve Growth Factor
- I. Introduction
- II. Neuritogenic Factors and Development ot the Nervous System
- III. Neurite Formation in Human Neuroblastoma Cells
- IV. Mechanism of Neurite Formation
- V. Concluding Remarks
- References
- Chapter 3. Pituitary Regulation by Gonadotropin-Releasing Hormone (GnRH): Gonadotropin Secretion, Receptor Numbers, and Target Cell Sensitivity
- I. Introduction
- II. Molecular Characteristics of GnRH
- III. Plasma Membrane Receptor for GnRH
- IV. Effector Coupling of GnRH Action
- V. Regulation of Gonadotrope Responsiveness to GnRH
- VI. Mechanisms Underlying the Regulation of GnRH Receptor Number
- VII. Conclusions: A Model for GnRH Action
- References
- Chapter 4. Thyrotropin-Releasing Hormone: Role of Polyphosphoinositides in Stimulation of Prolactin Secretion
- I. Introduction
- II. Calcium as Mediator of TRH-Induced Burst Prolactin Secretion
- III. TRH Effects on Phosphoinositide Metabolism
- IV. Coupling of TRH Receptor to Polyphosphoinositide Hydrolysis
- V. InsP3 and 1,2-DG as Intracellular Signals
- VI. Ca2+ and Lipid Second Messengers Mediate Biphasic Prolactin Secretion
- VII. Model of TRH Action
- References
- PART II: STEROID HORMONE ACTION
- Chapter 5. Steroid Effects on Excitable Membranes
- I. Introduction
- II. Organization of Steroid-Concentrating Excitable Cells
- III. Steroid Hormone Effects on Excitable Cells
- IV. Molecular Effects of Steroids on Membrane Properties
- V. Molecular Mechanisms of Steroid Hormone Action on Nonexcitable Cells
- VI. Conclusions and Questions
- References
- Chapter 6. Estradiol-Regulated Neuronal Plasticity
- I. Introduction
- II. Lordosis
- III. Sexual Dimorphisms
- IV. Reproductive Senescence
- V. E2-Induced Proteins,
- Note Added in Proof
- References
- Chapter 7. Steroid Hormone Influences on Cyclic AMP-Generating Systems
- I . Introduction
- II. Adenylate Cyclase
- III . Steroid Modulation of CAMP Metabolism
- IV. Mechanisms
- V. Summary
- References
- PART III: MAGNOCELLULAR NEURONS
- Chapter 8. Expression of the Oxytocin and Vasopressin Genes
- I. Introduction
- II. Precursor and Gene Structure
- III. Gene Regulation
- IV. Processing of the Precursors
- V. Expression of the Mutated Vasopressin Gene in Diabetes Insipidus (Brattleboro) Rats
- VI. Conclusions and Perspectives
- References
- Chapter 9. The Secretory Vesicle in Processing and Secretion of Neuropeptides
- I. Introduction
- II. Structure of Precursors and Cleavage Sites
- III. The Processing Enryrnes
- IV. The Secretory Vesicle as the Processing Environment
- V. Concluding Remarks
- References
- Chapter 10. Mammalian Neurosecretory Cells: Electrical Properties in Vivo and in Vitro
- I. Introduction
- II. Vasopressin Neurons
- III. Electrical Activity of Oxytocinergic Neurons
- References
- Index
- Contents of Recent Volumes
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