Muscle and Nonmuscle Motility

ContentsContributors Preface Contents of Volume 2 1. Molecular Basis of Contraction in Cross-Striated Muscles and Relevance to Motile Mechanisms in Other Cells I. Introduction II. Structure of Muscle Fibers III. Protein Components of the Filaments IV. Changes in the Band Pattern of Muscle during Contraction and Stretch V. Molecular Structure of the Filaments VI. Molecular Changes during Contraction and in Rigor VII. Some Biochemical and Physiological Implications of the Structural Results VIII. Structural Details of the Cross-Bridge Mechanism IX. Outstanding Problems and Future Work References 2. Macromolecular Assembly of Myosin I. Introduction II. Assembly of Myosin Filaments III. Assembly of Copolymers of Different Myosins (Hybridization) References 3. Macromolecular Assembly of Actin I. Introduction II. G-F Transformation of Actin III. Structure of F-Actin IV. Conformation and Interaction of Actin Monomer V. Interaction of F-Actin with Regulatory Proteins and Myosin VI. Actin and Motility VII. Concluding Remarks References 4. Regulation of Contractility I. Introduction II. One Aspect of the Troponin Mechanism: The Role of Troponin T III. General Aspects of the Regulatory Mechanism in Vertebrate Smooth Muscle IV. Characteristics of Aorta Leiotonin V. Troponin in Ascidian Smooth Muscle VI. A Regulatory Factor in Slime Mold VII. Concluding Remarks References5. The Regulation of Cytoplasmic Ca2+ Concentration in Muscle and Nonmuscle Cells I. Introduction II. The Sarcoplasmic Reticulum of Skeletal Muscle III. The Transport of Ca2+ by Cardiac Sarcoplasmic Reticulum IV. The Ca2+ Transport Activities of Cardiac Sarcolemma V. Smooth Muscle VI. The Regulation of Cytoplasmic Ca2+ Concentration in Nonmuscle Cells References Index