
Multi-Dimensional Liquid Chromatography
Description
Alles über E-Books | Antworten auf Fragen rund um E-Books, Kopierschutz und Dateiformate finden Sie in unserem Info- & Hilfebereich.
This text, organized by two leaders in the field, establishes a sound fundamental basis for the principles of the technique, followed by a discussion of important practical considerations. The book begins with an introduction to multi-dimensional separations and a discussion of the history and development of the technique over the past 40 years, followed by several chapters that provide a theoretical basis for development of 2D-LC methods, including foundational concepts regarding separation complementarity, under-sampling, and dynamics of liquid chromatography separations. Instrumentation for 2D-LC is discussed extensively, including practical aspects such as interface selection and setup. Building on this foundation, two separate chapters are focused on method development for non-comprehensive and comprehensive separations, followed by a chapter dedicated to data analysis. Finally, applications of 2D-LC in several fields ranging from pharmaceutical analysis to polymer science are summarized.
The book is an important resource for both students and practitioners who are already using 2D-LC or are interested in getting started in the field.
Key Features:
Demonstrates the conditions under which a 2D-LC method should be considered as an alternative to a 1D-LC method
Establishes a sound fundamental basis of the principles of the technique, followed by guidelines for method optimization
Provides a single source for technical knowledge advances and practical guidance described in recent literature
Assists with the initial decision to develop a 2D-LC method
Guides the reader in developing a high-quality method that meets the needs of their application
More details
Other editions
Additional editions


Persons
Professor Carr and his nearly 100 former graduate students and postdoctoral associates have published over 400 papers in a variety of areas of Analytical Chemistry including: electrochemistry, ion selective electrodes, thermochemistry, immobilized enzymes, and chromatography. He holds fourteen U.S. patents in areas related to chemical analysis and chromatography. Most recently, his research interests have focused on understanding the nature of solute-solvent interactions as they pertain to the prediction of retention, selectivity and optimization in chromatography. Additional areas of study include affinity chromatography, bio-separations, the theory of nonlinear chromatography, and the development of chemically and thermally stable supports for high performance liquid chromatography (HPLC) and most recently ultra-fast and comprehensive two-dimensional HPLC.
Dwight Stoll did his undergraduate work at Minnesota State University, Mankato, in plant biology and biochemistry. From 1999 to 2003 he worked as a research technician with ZirChrom Separations, Inc. For his graduate work he studied with Professor Peter Carr at the University of Minnesota from 2001-2007, where he worked on the development of Fast, Comprehensive Two-Dimensional Liquid Chromatography. In 2008, Dwight joined the Chemistry Department at Gustavus Adolphus College as an assistant professor, and was promoted to Professor in 2018. Since the fall of 2017 he has authored the monthly 'LC Troubleshooting' column for LCGC Magazine. In 2011 he was the recipient of LCGC's Emerging Leader in Chromatography Award, and received young investigator in separation science awards from the American Chemical Society and Eastern Analytical Symposium in 2015 and 2017. He has been named to The Analytical Scientist's lists of top analytical scientists three times, and in 2017 he received the Georges Guiochon Faculty Fellowship.
Professor Stoll's active research projects in his laboratory touch upon most aspects of multi-dimensional separation methodologies, including optimization strategies, characterization of selectivity in reversed-phase HPLC, instrument development, and applications in biopharmaceutical analysis. He is the author or co-author of 85 peer-reviewed publications and six book chapters in the area of separation science, speaks internationally on the topic, is a named co-inventor on four patents for separations technologies, and has instructed numerous short courses in two-dimensional liquid chromatography.
Content
System requirements
File format: PDF
Copy-Protection: Adobe-DRM (Digital Rights Management)
System requirements:
- Computer (Windows; MacOS X; Linux): Install the free reader Adobe Digital Editions prior to download (see eBook Help).
- Tablet/smartphone (Android; iOS): Install the free app Adobe Digital Editions or the app PocketBook before downloading (see eBook Help).
- E-reader: Bookeen, Kobo, Pocketbook, Sony, Tolino and many more (only limited: Kindle).
The file format PDF always displays a book page identically on any hardware. This makes PDF suitable for complex layouts such as those used in textbooks and reference books (images, tables, columns, footnotes). Unfortunately, on the small screens of e-readers or smartphones, PDFs are rather annoying, requiring too much scrolling.
This eBook uses Adobe-DRM, a „hard” copy protection. If the necessary requirements are not met, unfortunately you will not be able to open the eBook. You will therefore need to prepare your reading hardware before downloading.
Please note: We strongly recommend that you authorise using your personal Adobe ID after installation of any reading software.
For more information, see our eBook Help page.