Ageless
The New Science of Getting Older without Getting Old
1st Edition
Published on 24. December 2020
400 pages
978-1-5266-0827-7 (ISBN)
Description
'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans
'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent
'An exhilarating journey . . . Steele is a superb guide' Telegraph
'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday
Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it?
Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.
'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent
'An exhilarating journey . . . Steele is a superb guide' Telegraph
'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday
Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it?
Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.
More details
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
ISBN-13
978-1-5266-0827-7 (9781526608277)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Book
01/2022
Bloomsbury Publishing PLC
€16.50
Available immediately
Book
12/2020
Bloomsbury Publishing PLC
€44.76
Article exhausted; check different version
Person
Andrew Steele is a scientist, writer and campaigner. After a PhD in physics from the University of Oxford, he decided that ageing was the single most important scientific challenge of our time and switched fields to computational biology. He has worked at the Francis Crick Institute, using machine learning to decode our DNA. He lives in London.
Content
- Cover
- Half-Title Page
- Title Page
- Contents
- Introduction
- Part 1 An age-old problem
- Chapter 1 The age of ageing
- Chapter 2 On the origin of ageing
- Chapter 3 The birth of biogerontology
- The worm has turned 150
- Chapter 4 Why we age
- 2. Trimmed telomeres
- 3. Protein problems: autophagy, amyloids and adducts
- Autophagy
- Amyloids
- Adducts
- 4. Epigenetic alterations
- 5. Accumulation of senescent cells
- 6. Power struggle: malfunctioning mitochondria
- 7. Signal failure
- 8. Gut reaction: changes in the microbiome
- 9. Cellular exhaustion
- 10. Defective defences: malfunction of the immune system
- Fixing the hallmarks of ageing
- Part 2 Treating ageing
- Chapter 5 Out with the old
- Reinventing recycling: upgrading autophagy
- Amyloid
- Chapter 6 In with the new
- Improving immunity
- Modifying the microbiome
- Keeping protein pristine
- Chapter 7 Running repairs
- Can young blood teach old cells new tricks?
- Powering up mitochondria
- Repelling the attack of the clones
- Chapter 8 Reprogramming ageing
- Turning back the epigenetic clock
- Reprogramming biology and curing ageing
- Part 3 Living longer
- Chapter 9 The quest for a cure
- Chapter 10 How to live long enough to live even longer
- 2. Don't eat too much
- 3. Get some exercise
- 4. Get seven to eight hours of sleep a night
- 5. Get vaccinated and wash your hands
- 6. Take care of your teeth
- 7. Wear sunscreen
- 8. Monitor your heart rate and blood pressure
- 9. Don't bother with supplements
- 10. Don't bother with longevity drugs - yet
- 11. Be a woman
- Chapter 11 From science to medicine
- Notes and bibliography
- Notes
- Acknowledgements
- Index
- Copyright Page
