Section I Biophysical Chemistry, Metabolism, Second 1. Biophysical Chemistry of Physiological Solutions 2. Physiological Structure and Function of Proteins3. Structural Organization and Properties of Appendix: Exponential Time Course Membrane Lipids4. Cell Membranes and Model Membranes5. Lipid Domains and Biological Membrane Function6. Ultrastructure of Cells7. Energy Production and Metabolism8. Physiology of Mitochondria9. Signal Transduction10. Calcium as an Intracellular Second Messenger: Mediation by Calcium-Binding Proteins11. Regulation of Cellular Functions by Extracellular Calcium12. Cellular Responses to Hormones
Section II Membrane Potential, Transport Physiology, Pumps, and Exchangers13. Diffusion and Permeability14. Origin of Resting Membrane Potentials15. Gibbs-Donnan Equilibrium Potentials16. Mechanisms of Carrier-Mediated Transport: Facilitated Diffusion, Cotransport, and Countertransport17. Sodium Pump Function 18. Ca2 +-ATPases19. Na+-Ca2+ Exchange Currents20. Intracellular Chloride Regulation21. Osmosis and Regulation of Cell Volume22. Intracellular pH Regulation23. Membrane Transport in Red Blood Cells
Section III Membrane Excitability and Ion Channels24. Cable Properties and Propagation of Action Potentials25. Electrogenesis of Membrane Excitability26. Patch-Clamp Techniques and Analysis27. Structure and Mechanism of Voltage-Gated Ion Channels28. Biology of Neurons29. Ion Channels in Nonexcitable Cells30. Ion Channels in Sperm31. Biology of Gap Junctions32. Biophysics of the Nuclear Envelope33. Regulation of Ion Channels by Phosphorylation34. Direct Regulation of Ion Channels by G Proteins35. Developmental Changes in Ion Channels36. Regulation of Ion Channels by Membrane Proteins and Cytoskeleton
Section IV Ion Channels as Targets for Toxins, Drugs, and Genetic Diseases37. Ion Channels as Targets for Toxins38. Ion Channels as Targets for Drugs39. Ion Channels as Targets for Disease
Section V Synaptic Transmission and Sensory Transduction40. Ligand-Gated Ion Channels41. Synaptic Transmission42. Excitation-Secretion Coupling43. Stimulus-Response Coupling in Metabolic Sensor Cells44. Mechanosensitive Ion Channels in Eukaryotic Cells45. Sensory Receptors and Mechanotransduction46. Acoustic Transduction
Appendix: Self-Referencing Electrodes for the Measurement of Extracellular Potential and Chemical Gradients47. Cyclic Nucleotide-Gated Ion Channels48. Visual Transduction49. Gustatory and Olfactory Sensory Transduction50. Electroreceptors and Magnetoreceptors
Section VI Muscle and Other Contractile Systems51. Skeletal Muscle Action Potentials52. Cardiac Action Potentials53. Smooth Muscle Action Potentials and Electrical Profiles54. Excitation-Contraction Coupling in Skeletal Muscle55. Ca2+ Release from Sarcoplasmic Reticulum in Muscle56. Contraction of Muscles57. Amoeboid Movement, Cilia, and Flagella58. Centrin-Based Contraction and Bacterial Flagella59. Effects of High Pressure on Cellular Processes60. Electrocytes of Electric Fish
Section VII Protozoa and Bacteria61. Physiological Adaptations of Protists61. Physiology of Prokaryotic Cells
Section VIII Plant Cells, Photosynthesis, and Bioluminescence63. Plant Cell Physiology64. Photosynthesis65. Bioluminescence
Section IX Cell Division and Programmed Cell Death66. Regulation of Cell Division in Higher Eukaryotes67. Cancer Cell Properties68. Apoptosis69. Effects of Ionizing Radiation on Cells70. Review of Electricity and Cable Properties