Translational Research in Genetics and Genomics
Published on 2. April 2008
235 pages
978-0-19-971834-4 (ISBN)
Description
In this new book, noted geneticist and veteran OUP author, Moyra Smith, present a comprehensive critical review of the translation of genetic and genomic research into health care. Dr. Smith's motivation for writing is driven by the gap that exists between the rather amazing discoveries in medical genetics and genomics at basic science levels and the translation to disease management in single gene disorders, specific genetic syndromes, and complex genetic diseases. She also examines information technology in genetic medicine, sociocultural factors that impact provision of medical care, and medical education issues with regard to translational genetics in order to help prepare a work force that is better able to utilize evidence-based medicine and to accomodate the rapid changes in genetic and genomic health care.
More details
Other editions
Additional editions
Moyra Smith
Translational Research in Genetics and Genomics
Book
04/2008
Oxford University Press Inc
€87.20
Shipment within 15-20 days
Content
- Intro
- Contents
- 1. Isolation of Disease Genes Through Genomics
- 2. Advances in Genome Analysis: Discovery of Structural Variation and Genomic Dosage Differences in Health and Disease
- 3. Significance of DNA Sequence Changes for Diagnosis and Therapy
- 4. Epigenetics
- 5. Complex Diseases: Molecular Genetic Contributions to Elucidation of Etiopathogenesis of Late-Onset Neurodegenerative Diseases
- 6. Advances in Treatment of Single Gene Disorders Through Translational Science: Treatment With Small Molecules (Chaperones) and Gene-Based Therapies
- 7. From Gene Discovery in Genetic Syndromes to Identification of Therapeutic Agents
- 8. Impact of the Environment on the Genome
- 9. Molecular Defects in Cancer: Application to Therapy
- 10. Pharmacogenetics and Pharmacogenomics
- 11. Phenomes, Phenotypes, and Clinical Genetic Services
- References
- Index
- A
- B
- C
- D
- E
- F
- G
- H
- I
- J
- K
- L
- M
- N
- O
- P
- R
- S
- T
- U
- V
- W
- X
- Y
