Process Systems Engineering for Pharmaceutical Manufacturing
Published on 16. March 2018
698 pages
978-0-444-63966-0 (ISBN)
Description
Process Systems Engineering for Pharmaceutical Manufacturing: From Product Design to Enterprise-Wide Decisions, Volume 41, covers the following process systems engineering methods and tools for the modernization of the pharmaceutical industry: computer-aided pharmaceutical product design and pharmaceutical production processes design/synthesis; modeling and simulation of the pharmaceutical processing unit operation, integrated flowsheets and applications for design, analysis, risk assessment, sensitivity analysis, optimization, design space identification and control system design; optimal operation, control and monitoring of pharmaceutical production processes; enterprise-wide optimization and supply chain management for pharmaceutical manufacturing processes.
Currently, pharmaceutical companies are going through a paradigm shift, from traditional manufacturing mode to modernized mode, built on cutting edge technology and computer-aided methods and tools. Such shifts can benefit tremendously from the application of methods and tools of process systems engineering.
- Introduces Process System Engineering (PSE) methods and tools for discovering, developing and deploying greener, safer, cost-effective and efficient pharmaceutical production processes
- Includes a wide spectrum of case studies where different PSE tools and methods are used to improve various pharmaceutical production processes with distinct final products
- Examines the future benefits and challenges for applying PSE methods and tools to pharmaceutical manufacturing
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Ravendra Singh | Zhihong Yuan
Process Systems Engineering for Pharmaceutical Manufacturing: Volume 41
From Product Design to Enterprise-Wide Decision-Making
Book
03/2018
Elsevier
€247.60
Shipment within 15-20 days
Content
1. New Product Discovery and Development for Pharmaceutical IndustryCatherine Azzaro-Pantel2. The development of a pharmaceutical oral solid dosage formsRahamatullah Shaikh, Denise Croker, Donal O'Brien and Gavin Walker 3. Innovative Process Development and Production Concepts for Small-molecule API ManufacturingJohn Woodley4. Plantwide Technoeconomic Analysis and Separation Solvent Selection for Continuous Pharmaceutical Manufacturing: Ibuprofen, Artemisinin and DiphenhydramineDimitrios Gerogiorgis, Samir Diab and Hikaru Jolliffe 5. Flowsheet Modeling of a Continuous Direct Compression ProcessSeongkyu Yoon6. Plant-wide Dynamic Model for the Integrated Continuous Pharmaceutical Process: Design of the RecycleBrahim Benyahia7. Advanced Multi-phase Hybrid Model Development of Fluidized Bed Wet Granulation ProcessesRohit Ramachandran, Ashutosh Tamrakar and Dheeraj R. Devarampally 8. Global sensitivity, feasibility and flexibility analysis of continuous pharmaceutical manufacturing processesMarianthi Ierapetritou and Zilong Wang 9. Crystallization process monitoring and control using process analytical technologyLevente Simon, Elena Simone and Kaoutar Abbou Oucherif 10. BioProcess Performance Monitoring using Multi-way Interval Partial Least SquareJulian Morris, Jie Zhang and Shallon Stubbs 11. Process Dynamics, and control of API manufacturing and purification processeMaitraye Sen, Ravendra Singh and Rohit Ramachandran 12. PAT for pharmaceutical manufacturing process involving solid dosages formsAndrés David Román-Ospino, Carlos Alberto Ortega-Zuniga, Vanessa Cardenas and Ravendra Singh 13. Model-based control system design and evaluation for continuous tablet manufacturing processes (via direct compaction, via roller compaction, via wet granulation) Ravendra Singh14. Fast Stochastic Model Predictive Control of End-to-end Continuous Pharmaceutical ManufacturingRichard D. Braatz, Ali Mesbah, Joel A. Paulson, Stefan Streif and Rolf Findeisen 15. Advanced Control for the Continuous Dropwise Additive Manufacturing of Pharmaceutical ProductsZoltan Nagy, Gintaras Reklatis and Elcin Icten 16. Control System Implementation and Plant-Wide Control of Continuous Pharmaceutical Manufacturing Pilot Plant (End-To-End Manufacturing Process)Richard Lakerveld17. Automation of continuous pharmaceutical manufacturing processRavendra Singh18. Implementation of control system into continuous pharmaceutical manufacturing pilot-plant (powder to tablet)Ravendra Singh19. Monitoring and control of a continuous tumble mixerCarlos Velazquez Figueroa, Leonel Quiñones and Miguel A. Florian Algarin 20. Flexible Continuous Manufacturing -- Based on S88 Batch Standards and Object Oriented DesignPaul Brodbeck21. Planning Pharmaceutical Clinical Trials under Outcome UncertaintySelen Cremaschi and Brianna Christian 22. Integrated production planning and inventory management in a multinational pharmaceutical supply chainNaresh Susarla and IA Karimi 23. Optimal Production of Biopharmaceutical ManufacturingLazaros Papageorgiou and Songsong Liu 24. Perspective on PSE in pharmaceutical process development and innovation-views from academiaRafiqul Gani, John Woodley and Emmanouil Papadakis
