Neurotransmitters
Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
Published on 22. October 2013
312 pages
978-1-4831-5475-6 (ISBN)
Description
Advances in Pharmacology and Therapeutics, Volume 2: Neurotransmitters contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neurotransmitters, their pharmacology, and their therapeutic applications. Topics covered range from the functions of GABA to the interdependence of neurotransmitter systems in the central nervous system (CNS). This volume is comprised of 24 chapters and opens with a discussion on the role of GABA systems in Huntington's disease and schizophrenia. The reader is then introduced to the stereospecific actions of GABA analogues; interactions between serotonin and noradrenalin containing neurons; immunofluorescent staining of serotonin in the CNS; and plasticity of transmitter functions in sympathetic neurons developing in cell culture. The following chapters explore the molecular mechanisms underlying the modulation of catecholamine release from the adrenal medulla; pre-and postsynaptic regulation of catecholamine neurotransmitters; the role of GABA-ergic component in the mechanism of action of neurotropic drugs; and pre-and postsynaptic action of GABA in the mammalian spinal cord. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.
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Content
IntroductionGABA: Simple Molecule with Complex Functions GABA Systems in Human Brain in Huntington's Disease and Schizophrenia Stereospecific Actions of GABA Analogues Barbiturates, Benzodiazepines and the GABA System Kinetics of GABA Action at the Crayfish Neuromuscular Junction A Molecular Mechanism for the Action of Benzodiazepines on GABA-Ergic Transmission Toward a Rational Pharmacology of the GABA SystemInterdependence of Neurotransmitter Systems in the CNS Physiology and Pharmacology of Ganglionic Synapses as Models for Central Transmission Microphysiological and Pharmacological Studies on Transmitters in the Substantia nigra Studies of the Interdependence of Neurotransmitter Systems by Micro-Biochemical Approaches Role of Various Nigral afferences on the Activity of the Nigrostriatal Dopaminergic Pathways Interactions between Serotinin and Noradrenalin Containing Neurons: Link Between The Raphe System and the Locus coeruleus Histochemistry of Transmitter Interactions - Neuronal Coupling and Coexistence of Putative Transmitters Concluding RemarksPharmacology of Neurotransmitters: New Vistas Immunofluorescent Staining of Serotonin in the Central Nervous System Excitatory Amino Acids: Receptor Differentiation by Selective Antagonists and Role in Synaptic Excitation Histaminergic Systems in Brain The Action of Substance P on Motoneurons of the Isolated Rat Spinal Cord Plasticity of Transmitter Functions in Sympathetic Neurons Developing in Cell Culture Is There a Neurotransmitter Code in the BrainInvited Lectures Molecular Mechanisms in the Modulation of Catecholamine Release from the Adrenal Medulla Some Structural Features of Amine Uptake Mechanisms Pre- and Postsynaptic Regulation of Catecholamine Neurotransmitters GABA-Ergic Component in the Mechanism of Action of Neurotropic Drugs Pre- and Postsynaptic Action of GABA in the Mammalian Spinal CordIndex
