Metal Ions in Biological Systems
Volume 36: Interrelations Between Free Radicals and Metal Ions in Life Processes
1st Edition
Published on 4. May 2018
848 pages
978-1-351-43213-9 (ISBN)
Description
Continues the tradition of excellence established in previous volumes in this acclaimed series. Volume 36 focuses on the vibrant research area concerning the interrelation between free radicals and metal ions and their resulting effects on life processes; it offers an authoritative and timely account of this fascinating area of research in 21 chapters.
Reviews / Votes
"This book will be of great interest to all interested in the role of metal ions in biology."---Applied Organometallic Chemistry Journal
". . .recommend[ed]. The editors deserve congratulation in selecting a first-rate group of authors and getting them to deliver."
---Free Radical Research
More details
Series
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Product notice
Reflowable
ISBN-13
978-1-351-43213-9 (9781351432139)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Astrid Sigel | Helmut Sigel
Metal Ions in Biological Systems
Volume 36: Interrelations Between Free Radicals and Metal Ions in Life Processes
Book
03/1999
1st Edition
CRC Press
€173.61
Shipment within 15-20 days
Persons
Content
The mechanism of Fenton-like reactions and their importance for biological systems - a biologist's view; reactions of aliphatic carbon-centred and aliphatic-peroxyl radicals with transition-metal complexes as a plausible source for biological damage induced by radical processes; free radicals as a result of dioxygen metabolism; free radicals as a source of uncommon oxidation states of transition metals; biological chemistry of copper-zinc superoxide dismutase and its link to amyotrophic lateral sclerosis; DNA damage mediated by metal ions with special reference to copper and iron; radical migration through the DNA helix - chemistry at a distance; involvement of metal ions in lipid peroxidation - biological implications; formation of methemoglobulin and free radicals in erythrocytes; role of free radicals and metal ions in the pathogenesis of Alzheimer's disease; metal binding and radical generation of proteins in human neurological diseases and aging; thiyl radicals in biochemically important thiols in the presence of metal ions; methymercury-induced generation of free radicals - biological implications; role of free radicals in metal induced carcinogenesis; pH-dependent organocobalt source for active radical species - a new type of anticancer agents; detection of chromatin-associated hydroxyl radicals generated by DNA-bound metal compounds and antitumor antibiotics; nitric oxide (NO) - formation and biological roles in mammalian systems; chemistry of peroxynitrite and its relevance to biological systems; novel nitric oxide-liberating heme proteins from the saliva of bloodsucking insects; nitrogen monoxide-related disease and nitrogen monoxide scavengers as potential drugs; therapeutics of nitric oxide modulation.
