Recent Advancement in Prodrugs
1st Edition
Published on 13. May 2020
350 pages
978-1-000-05797-3 (ISBN)
Description
Recent Advancement in Prodrugs
Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations.
Key features
Covers recent advancements in development of prodrugs
Presents balanced synthesis and applications of prodrug chemistry
Discusses broad spectrum of prodrug categories and outlines industrial applications
Reviews prodrugs in cancer nanomedicine, its therapy and treatment
Elucidates mathematical models to study the kinetics of prodrugs
This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations.
Key features
Covers recent advancements in development of prodrugs
Presents balanced synthesis and applications of prodrug chemistry
Discusses broad spectrum of prodrug categories and outlines industrial applications
Reviews prodrugs in cancer nanomedicine, its therapy and treatment
Elucidates mathematical models to study the kinetics of prodrugs
This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
More details
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
College/higher education
Professional and scholarly
Illustrations
27 Tables, black and white; 16 Illustrations, color; 161 Illustrations, black and white
ISBN-13
978-1-000-05797-3 (9781000057973)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Kamal Shah | Durgesh Nandini Chauhan | Nagendra Singh Chauhan
Recent Advancement in Prodrugs
Book
05/2020
1st Edition
CRC Press
€256.30
Shipment within 15-20 days
Persons
Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Pradeep Mishra
Content
Recent advancements in New drug design and development of prodrugs. Codrugs: Optimum use through prodrugs. Role of Prodrugs in Drug Design. Prodrugs for enhancement of lipophilicity. Lipidic Prodrugs for Drug Delivery: Opportunities and Challenges. The progress of prodrugs in drug solubility. Prodrugs for CNS drug delivery. Prodrugs for Cancer Treatment. Prodrugs in cancer nanomedicine and therapy. Nitroreductases in prodrug therapies. Prodrug approach using carboxylesterase: Different substrate specificities of human carboxylesterase isozymes. Mathematical models for ADME of prodrugs. Prodrug Approaches for Natural Products. Biotechnology based prodrug approach for cell-specific targeting: its theoretical basis and application.
