Peripheral Nerve Disorders
Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)
Published on 17. August 2013
1008 pages
978-0-444-63355-2 (ISBN)
Description
Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities.
- Covers both hereditary and cryptogenic neurologic disorders
- Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology
- Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy
More details
Edition
New ed.
Language
English
Place of publication
Chantilly
United States
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-444-63355-2 (9780444633552)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Book
09/2013
3rd Edition
Elsevier
€253.50
Shipment within 15-20 days
Content
Section 1 Introduction1. Prelude to the peripheral neuropathiesSection 2 Structure and function2. Microscopic anatomy: normal structures; 3. Gross anatomy and development of the peripheral nervous system; 4. Physiology and pathophysiology of myelinated nerve fibers; 5. Biology of Schwann cells; 6. Neurophysiological approach to disorders of peripheral nerve; 7. Testing autonomic functions; 8. Imaging of the peripheral nervous system; 9. The nerve biopsy: indications, technical aspects and contribution; 10. The cutaneous nerve biopsy: Technical aspects, indications, and contribution; 11. Antibody testing in peripheral nerve disorders; 12. DNA testing in hereditary neuropathiesSection 3 Clinical aspects13. Examination and clinical care of the patient with neuropathy; 14. How to explore a patient with chronic axonal neuropathy; 15. Evaluation of a patient with suspected chronic demyelinating polyneuropathy; 16. Sensory-motor assessment in clinical research trials; 17. Management of painful neuropathiesSection 4 Plexus and compression lesions18. Diagnosis of brachial and lumbosacral plexus lesions; 19. Compression and entrapment neuropathies; 20. Facial nerve palsy and hemifacial spasmSection 5 Inflammatory root and nerve lesions21. The Guillain-Barré syndrome; 22. Chronic inflammatory demyelinating polyneuropathy; 23. Treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP); 24. Multifocal motor neuropathy 25. Neuropathy and monoclonal gammopathySection 6 Neuropathy in connective tissue disorders26. Vasculitic neuropathy; 27. Sarcoidosis of the peripheral nervous systemSection 7 Neuropathy in infectious disorders28. Leprous neuropathy; 29. HIV peripheral neuropathy; 30. Human t-cell leukemia virus (HTLV) associated neuropathy; 31. Herpes virus infection of the peripheral nervous system; 32. Lyme neuroborreliosisSection 8 Neuropathy and metabolic disorders33. Diabetic neuropathy; 34. Biology of diabetic neuropathy; 35. Uremic neuropathy; 36. Porphyric neuropathy; 37. Fabry's disease; 38. Transthyretin familial amyloid polyneuropathy; 39. Hereditary gelsolin amyloidosisSection 9 Neuropathy and malignancy40. Malignant cell infiltration in the peripheral nervous system; 41. Paraneoplastic neuropathySection 10 Cryptogenic, Traumatic and Iatrogenic neuropathies42. Drug induced neuropathies; 43. Late radiation injury to peripheral nerves; 44. Neuromuscular complications of critical illness; 45. The surgery of peripheral nerves (including tumours); 46. Neuropathy in the elderlySection 11. Familial neuropathies47. Dominant Charcot-Marie-Tooth syndrome and cognate disorders; 48. Recessively transmitted predominantly motor neuropathies; 49. Early onset childhood monogenic neuropathies; 50. Hereditary sensory and autonomic neuropathies; 51. Peripheral nerve involvement in hereditary cerebellar and multisystem degenerative disorders; 52. Giant axonal neuropathy; 53. Neurofibromatosis 1(NF1), diagnosis and management; 54. Neurofibromatosis type 2 (NF2) diagnosis and management
