Polyphenols
Description
Understand polyphenols and their benefits with this comprehensive overview
Polyphenols are a group of beneficial compounds--including phenolic acids, flavonoids, anthocyanins, and others--that can be found in a vast range of plants and plant-based foods. Their health benefits and the variety of their applications in functional foods, dietary supplements, and similar areas have made polyphenols a $1 billion market, a figure that is expected to more than double in the next decade. This has placed increased emphasis on areas of cutting-edge research such as the use of bio-based nanodelivery systems to improve the oral bioavailability of polyphenols.
Polyphenols constitutes a comprehensive introduction to these compounds, their health benefits, and their potential nutraceutical applications. It incorporates both the biochemical fundamentals of polyphenols and their precise potential to prevent numerous common diseases. The result is an essential reference for a vital, growing area of research and industry.
Polyphenols readers will also find:
* Detailed coverage of polyphenols' occurrence, bioactivity, and technological applications
* In-depth discussion of nano-based delivery systems to increase polyphenols' therapeutic efficacy and oral bioavailability and to reduce required dosages
* Guidance for developing treatments for cancers, cardiovascular diseases, inflammatory conditions, and more
Polyphenols is ideal for food scientists and manufacturers, medicinal chemists, pharmaceutical scientists, and any biochemical or biomedical researcher or professional working with polyphenols or plant-based foods.
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Person
Mithun Rudrapal, PhD, is Associate Professor of the Department of Pharmaceutical Sciences, School of Biotechnology and Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research, Guntur, India. He has published extensively on plant-based compounds and their therapeutic and nutritional applications.
Content
List of Contributors vii
Preface xiii
1 Food Polyphenols: Antioxidant Properties and Health Benefits 1
Pruthvi G.R, Apoorva M.R., Anuthilakesh T., Bhargavi K., Nithish G.S., and Raghu Ram Achar
2 Plant Polyphenols as Nutraceuticals and Their Antioxidant Potentials 21
Neelesh Kumar Nema, Nayana Rajan, Merin Babu, Sachithra Sabu, Swapnil Devidas Khamborkar, Smitha Sarojam, Linson Cheruveettil Sajan, Aneena Peter, Baby Kumaranthara Chacko, and Viju Jacob
3 Polyphenols: Plant-based Nutraceuticals in Human Health 45
Monalisa Kesh and Sachin Goel
4 Nanotechnological Approach in Nutraceuticals 67
Manohar M.V., Amogha G. Paladhi, Sugumari Vallinayagam, and Mithun Rudrapal
5 Polyphenols: Nutraceutical and Nanotherapeutic Approaches 82
Mustansir Bhori, Ameyota De, Shreya Das, Aayushi Kadam, Jyotirmoi Aich, and Kanchanlata Tungare
6 Polyphenols in Food Products - Nutraceutical Applications 105
André M. Oliveira and Mithun Rudrapal Copyrighted Material
7 Functionalization of Food Polyphenols for Nanodeliveries 134
Koyel Kar
8 Nanodeliveries of Food Polyphenols as Nutraceuticals 155
Santwana Palai and Mithun Rudrapal
9 Polyphenol Rich Extracts from Spices and Nanodelivery Systems 176
Neelesh Kumar Nema, Baby Kumaranthara Chacko, and Viju Jacob
10 Nanodelivery of Polyphenols as Nutraceuticals in Anticancer Interventions 188
Kamoru A. Adedokun, Sikiru O. Imodoye, Zwanden S.Yahaya, Ifeoluwa T. Oyeyemi, Ibrahim O. Bello, Mujidat T. Adeyemo-Imodoye, Malik A. Sanusi, and Ramat T. Kamorudeen
11 Nanodelivery of Polyphenols as Nutraceuticals for CNS Disorders 225
Puneet K. Samaiya, Rakesh Sagar, Sharad P. Pandey, Gourav Jain, and Abhishek K. Sah
12 Nanodelivery of Polyphenols as Nutraceuticals for Neurological Disorders 248
Arpita Paul, Madhusmita Gogoi, and Kamaruz Zaman
13 Addressing Antimicrobial Resistance by Repurposing Polyphenolic Phytochemicals with Novel Antibacterial Potential 260
Mithun Rudrapal, Biswatrish Sarkar, Prashanta Kumar Deb, Atul R. Bendale, and Akhil Nagar
14 Toxicity of Polyphenols Consumed as Food and Nutraceuticals: Remedies through Nanotherapeutic Approaches 290
Anyanwu O. Gabriel and Ogah F. Chinenye
15 Nanodelivery of Food Polyphenols for Nutraceutical Applications 312
Aamena Yusuf, Tanisha Ambawat, Sneha Dokhale, Shine Devarajan, and Samiksha Garse
16 Polyphenols in Food Products and Nutraceuticals: Bioavailability and Pharmacokinetic Issues 343
Priaunsh Dutt, Yashika Shadija, Sneha Dokhale, Sweta Das, Shine Devarajan, and Samiksha Garse
Index 361
List of Contributors
Raghu Ram Achar
Division of Biochemistry, School of Life Sciences
JSS Academy of Higher Education and Research
Mysuru
Karnataka
India
Kamoru A. Adedokun
Roswell Park Comprehensive Cancer Center
University at Buffalo
Buffalo
NY
USA
Mujidat T. Adeyemo-Imodoye
Department of Medical Laboratory Science
Somolu General Hospital
Lagos Health Service Commission
Lagos State
Nigeria
Jyotirmoi Aich
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Tanisha Ambawat
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra, India
Anuthilakesh T.
Division of Biochemistry, School of Life Sciences
JSS Academy of Higher Education and Research
Mysuru
Karnataka
India
Anyanwu O. Gabriel
Department of Biochemistry
Bingham University
Karu
Nasarawa
Nigeria
Apoorva M.R.
Division of Biochemistry, School of Life Sciences
JSS Academy of Higher Education and Research
Mysuru
Karnataka
India
Merin Babu
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Ibrahim O. Bello
Department of Biological Sciences
Southern Illinois University Edwardsville
Edwardsville
IL
USA
Atul R. Bendale
Mahavir Institute of Pharmacy
Nashik
Maharashtra
India
Bhargavi K.
Division of Biochemistry, School of Life Sciences
JSS Academy of Higher Education, and Research
Mysuru
Karnataka
India
Mustansir Bhori
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Baby Kumaranthara Chacko
C.V.J. Creative Centre
Bio Ingredients, Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Shreya Das
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Sweta Das
B. K. Birla College
Birla College Campus Rd
Kalyan
Maharashtra
India
Ameyota De
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Prashanta Kumar Deb
Department of Pharmaceutical Sciences and Technology
Birla Institute of Technology
Ranchi
Jharkhand
India
Shine Devarajan
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Belapur
Navi Mumbai
Maharashtra
India
Sneha Dokhale
B. K. Birla College
Birla College Campus Rd
Kalyan
Maharashtra
India
Priaunsh Dutt
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Samiksha Garse
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra, India
Sachin Goel
Department of Biological Sciences and Engineering
Netaji Subhas University of Technology
New Delhi
India
Madhusmita Gogoi
Department of Pharmaceutical Sciences
Faculty of Science and Engineering
Dibrugarh University
Dibrugarh
Assam
India
Sikiru O. Imodoye
Huntsman Cancer Institute
University of Utah
Salt Lake City
UT
USA
Viju Jacob
Nutraceuticals Division, Bio Ingredients
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Ernakulam
Kerala
India
C.V.J. Creative Centre
Bio Ingredients, Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Gourav Jain
Department of Pharmacy
Shri Govindram Seksariya Institute of Technology & Science (SGSITS)
Indore
Madhya Pradesh
India
Aayushi Kadam
Department of Food and Human Nutritional Sciences
University of Manitoba
Canada
Ramut T. Kamorudeen
Department of Public Health
University of South
Wales, Pontypridd
UK
Koyel Kar
Department of Pharmaceutical Chemistry
BCDA College of Pharmacy & Technology
Hridaypur
West Bengal
India
Monalisa Kesh
Amity Institute of Biotechnology
Amity University Uttar Pradesh
Noida
India
Swapnil Devidas Khamborkar
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Manohar M.V.
Centre of excellence in Molecular Biology & Regenerative Medicine
Department of Biochemistry
JSS Medical College, JSS-AHER
Mysuru
Karnataka, India
Akhil Nagar
Department of Pharmaceutical Chemistry
R. C. Patel Institute of Pharmaceutical Education and Research
Shirpur
Maharashtra
India
Neelesh Kumar Nema
Nutraceuticals Division
Bio Ingredients, Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Ernakulam
Kerala
India
Nithish G.S.
Indian Institute of Science Education and Research Tirupati
C/O Sree Rama Engineering College (Transit Campus Mangalam)
Tirupati
Andhra Pradesh
India
Ogah F. Chinenye
Department of Biochemistry
Bingham University
Karu
Nigeria
André M. Oliveira
Federal Centre of Technological Education of Minas Gerais (CEFET-MG)
Alameda das Perdizes
Contagem
MG
Brazil
Ifeoluwa T. Oyeyemi
Department of Biosciences and Biotechnology
University of Medical Sciences
Ondo
Nigeria
Department of Chemistry and Biochemistry
Old Dominion University
Hampton Boulevard
Norfolk
VA
USA
Amogha G Paladhi
Department of Botany
CHRIST (Deemed to be) University
Bengaluru
Karnataka
India
Santwana Palai
Department of Veterinary Pharmacology & Toxicology
College of Veterinary Science and Animal Husbandry
Odisha University of Agriculture & Technology
Bhubaneswar
Odisha
India
Sharad P. Pandey
Department of Pharmacy
Shri Govindram Seksariya Institute of Technology & Science (SGSITS)
Indore
Madhya Pradesh
India
Arpita Paul
Department of Pharmaceutical Sciences
Faculty of Science and Engineering
Dibrugarh University
Dibrugarh
Assam
India
Aneena Peter
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Pruthvi G.R.
Division of Biochemistry
School of Life Sciences
JSS Academy of Higher Education and Research
Mysuru
Karnataka
India
Nayana Rajan
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Mithun Rudrapal
Department of Pharmaceutical Sciences
School of Biotechnology and
Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research
Guntur
India
Sachithra Sabu
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Rakesh Sagar
Department of Pharmacy
Shri Govindram Seksariya Institute of Technology & Science (SGSITS)
Indore
Madhya Pradesh
India
Abhishek K. Sah
Department of Pharmacy
Shri Govindram Seksariya Institute of Technology & Science (SGSITS)
Indore
Madhya Pradesh
India
Linson Cheruveettil Sajan
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Puneet K. Samaiya
Department of Pharmacy
Shri Govindram Seksariya Institute of Technology & Science (SGSITS)
Indore
Madhya Pradesh
India
Malik A. Sanusi
Department of Biochemistry and Molecular Biology
Obafemi Awolowo University
Ile-Ife
Osun State
Nigeria
Biswatrish Sarkar
Department of Pharmaceutical Sciences and Technology
Birla Institute of Technology
Ranchi
Jharkhand
India
Smitha Sarojam
Synthite Industries Pvt. Ltd.
Synthite Valley
Kadayiruppu
Kerala
India
Yashika Shadija
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Kanchanlata Tungare
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
Navi Mumbai
Maharashtra
India
Sugumari Vallinayagam
Department of Biotechnology
Vel Tech Rangarajan Dr. Sagunthala R and D Institute of Science and Technology
Chennai
Tamil Nadu
Zwanden S. Yahaya
Department of Pharmaceutics and Industrial Pharmacy
Faculty of Pharmaceutical Sciences
Kaduna State University,
Kaduna
Nigeria
Aamena Yusuf
School of Biotechnology and Bioinformatics
D Y Patil Deemed to be University
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