Genetic Mechanisms of Development

ContentsContributors and Presiding Chairmen I. Prokaryotic Systems of Analysis Regulation of Bacteriophage ¿ Development I. Introductory Comments II. Stages of Phage ¿ Development III. The Lytic Pathway IV. The Lysogenic Pathway V. Summary of Phage ¿ Development References The Question of Gene Regulation in Sporulating Bacteria I. Introduction II. RNA Polymerase Loses Vegetative Template Specificity during Sporulation III. Genetic Evidence that the Loss of Vegetative Specificity is Critical for Sporulation IV. In Vitro Transcription of Phage Fe DNA Requires a Sigma Factor V. Loss of Sigma Activity during Sporulation VI. In Vitro Transcription of the B. subtilis Ribosomal RNA Genes VII. The Switch From Vegetative to Sporulation Transcription VIII. Isolation of a New RNA Polymerase Subunit during Sporulation IX. RNA Polymerase and Differentiation References Genetic Control of Bacteriophage T4 Morphogenesis I. T4 as a Model System II. Outlining the Process of T4 Morphogenesis III. Self-Assembly and Non-Self-Assembly in the Morphogenetic Pathway IV. Conclusion References II. Eukaryotic Systems of Analysis Genetics of Sperm Development in Drosophila I. Introduction II. The Sequential Events of Spermiogenesis III. Y-Chromosome Function in Spermiogenesis IV. Autosomal and X-Linked Gene Function in Spermiogenesis V. Cellular Specificity of Gene Activity in Spermiogenesis VI. Concluding Remarks References Genetic Control of Determination in the Drosophila Embryo I. Introduction II. Early Embryogenesis of Drosophila III. Developmental Potential of Cleavage Nuclei IV. Determination of Blastoderm Cells V. Genetic Control of Determination VI. Conclusion References Mapping of Behavior in Drosophila Mosaics I. Introduction II. Mutants with Simple Foci III. Complex Foci IV. Discussion V. Conclusion References Developmental Genetics of the Axolotl I. Introduction II. Genes Affecting the Oocyte Cytoplasm III. Genes Affecting the Induction of the Heart and the Eye IV. Comments on Other Genes in the Axolotl V. Amphibians Other than the Axolotl VI. Summary References Necessary Conditions for Gene Expression during Early Mammalian Development I. Introduction II. Biochemical Changes during Early Mammalian Development III. Is New Genetic Information Required for Development? IV. Dependence of Differentiation and Development on Cell Interactions within the Embryo V. Dependence of Development on the Maternal Environment-Preimplantation VI. Dependence of Development on the. Maternal Environment-Postimplantation VII. Conclusions References Estrogen Regulation of Ovalbumin mRNA Content and Utilization I. Hormonal Regulation of Ovalbumin Synthesis II. Assay and Isolation of Ovalbumin mRNA III. The Mechanism of "Superinduction" of Ovalbumin by Actinomycin D IV. Discussion References Sequence Organization in the Genome of Xenopus laevis I. Introduction II. The Repetitive DNA of the Xenopus Genome III. Binding to Hydroxyapatite of DNA of Various Fragment Lengths IV. Evidence for Sequence Interspersion from Melting Experiments V. The Length of Repetitive and Nonrepetitive Sequence Elements VI. Discussion References III. Somatic Cell Genetics Systems of Analysis Regulation of Differentiated Phenotype in Heterokaryons I.