Clinical and Translational Science

List of ContributorsForewordAcknowledgmentsIntroduction to Clinical ResearchPart I Fundamental Principles 1 Patient-Oriented Research: Clinical Pathophysiology and Clinical Therapeutics 2 Clinical TrialsPart II Approaches 3 Experimental Design 4 Introduction to Biostatistics Ideas 5 Measurement of Biological Materials 6 Imaging Tools in Human Research 7 Imaging Tools in Cardiovascular Research 8 Nanotechnology in Clinical and Translational Research 9 The Use of Questionnaires and Surveys 10 Information TechnologyPart III Infrastructure 11 Clinical and Translational Science Infrastructure 12 Industry-Sponsored Clinical Research in AcademiaPart IV Education, Training and Career Choices 13 Training Basic, Clinical and Translational Investigators 14 A Stepwise Approach to a Career in Translational Research 15 Physician Careers in IndustryPart V Funding 16 Governmental Support of Research 17 Support of Health Research by Private Philanthropy 18 Pharmaceutical and Biotechnology Sector Support of ResearchPart VI Human Genetics 19 Introduction to Human Genetics 20 Epidemiologic and Population Genetic Studies 21 Pharmacogenetics of Drug MetabolismPart VII Human Pharmacology 22 Introduction to Clinical Pharmacology 23 Toxicology and Genetics of Adverse Drug Events 24 Good Clinical Practice and Good Laboratory Practice 25 Modern Drug Discovery and DevelopmentPart VIII Societal Context of Human Research 26 Translating Science to the Bedside: The Innovation Pipeline 27 Regulatory Environment 28 Ethical Issues in Translational Research and Clinical Investigation 29 Clinical Research in the Public EyePart IX Research in Special Populations 30 Acute Illnesses, Critical Care, Emergency and Surgical Patients 31 Psychiatric Disorders 32 Geriatrics 33 PediatricsPart X Population-Based Research 34 Pharmacoeconomics: The Economic Evaluation of New Medical Technology 35 Introduction to Epidemiology 36 Health Services Research: Translating Discovery and Research into Practice and PolicyPart XI Prospectus 37 The Future of Clinical ResearchIndex