Biomedical Engineering e-Mega Reference

Name: Biomedical Engineering e-Mega Reference
Brand: Academic Press
Price: 80.95 EUR
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Buddy D. Ratner Alkis Constantinides University of Pennsylvania Dyro M. S. and Biomedical Electronics Engineering Richard Kyle Bernhard Preim Sverre Grimnes Frederick J. Schoen Daniel A. Vallero Orjan G. Martinsen Allan S. Hoffman Jack E. Lemons John Semmlow W. Bosseau Murray Reinaldo Perez Isaac Bankman Stanley Dunn Yoshito Ikada Prabhas V. Moghe(Author)

Academic Press

Published on 23. March 2009

816 pages

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978-0-12-374647-4 (ISBN)

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Buddy D. Ratner, Michael L. and Myrna Darland Endowed Chair in Bioengineering and Professor of Chemical Engineering at the University of Washington, received his Ph.D. (1972) in polymer chemistry from the Polytechnic Institute of Brooklyn. From 1985-1996 he directed the NIH-funded National ESCA and Surface Analysis Center for Biomedical Problems (NESAC/BIO), and in 1996 he assumed the directorship of University of Washington Engineered Biomaterials (UWEB), an NSF Engineering Research Center. He is the editor of the Journal of Undergraduate Research in Bioengineering, a past president of the Society for Biomaterials and author of 400 scholarly works. Ratner is a fellow of the American Institute of Medical and Biological Engineering (AIMBE), the American Vacuum Society and a Fellow, Biomaterials Science and Engineering (FBSE). He served as president of AIMBE, 2002-2003. He is vice president of the Tissue Engineering Society International (TESI) 2003-2005. In 2002 Ratner was elected a member of the National Academy of Engineering, USA, and in 2004 he won the Founder's Award for the Society For Biomaterials. His research interests include biomaterials, tissue engineering, polymers, biocompatibility, surface analysis of organic materials, self-assembly, nanobiotechnology and RF-plasma thin film deposition. Summary of Buddy Ratner's awards and honors: 1989 Clemson Award for Contributions to the Biomaterials Literature 1990 Burlington Resources Foundation Faculty Achievement Award for Outstanding Research 1991 Perkin-Elmer Physical Electronics Award for Excellence in Surface Science 1991-1992 President, Society For Biomaterials 1993 Founding Fellow, American Institute of Medical and Biological Engineering (AIMBE) 1993 Fellow, American Vacuum Society; Vice President, AIMBE 1993 Fellow, Society For Biomaterials; Van Ness Lecturer, Rensselaer Polytechnic Institute 1998 C.M.A. Stine Award in Materials Science (AIChE); American VacuuJohn Semmlow was a professor in the Department of Biomedical Engineering of Rutgers University and in the Department of Surgery of Robert Wood Johnson Medical School UMDNJ for 32 years. Over that period he published over 100 review journal articles and has been appointed a Fellow of the IEEE, the AIMBE, and the BMES. He retired in June of 2010, but still remains active in research, particularly cardiovascular diagnosis and human motor control. He is actively pursuing a 'second career' as an artist, designing and building computer controlled kinetic art: sculptures that move in interesting and intriguing ways.Reinaldo Perez is Senior Engineer and Member of the Technical Staff at the Jet Propulsion Laboratory, California Institute of Technology in Pasadena, California. For the past three years, Dr. Perez has also been working with Lockheed Martin Astronautics (LMA) on the Mars Surveyor series. His primary work has been as a designer of spacecraft (or satellite) subsystems and ground support hardware for increased reliability in space environments, focusing on wireless communications hardware with built-in immunity to many kinds of noise and interference problems. He is a senior member of the IEEE, AIAA, and AIP, and serves as a board member of the Applied Computational Electromagnetics Society (ACES). In addition, Dr. Perez is an associate editor of the IEEE EMCS Journal, as well as Editor of the ACES Newsletter.Isaac Bankman is affiliated with Johns Hopkins University

Content

Front Cover
Note from the Publisher
BiomedicalEngineeringDesk Reference
Copyright Page
Contents
Author Biographies
Section One Introduction
Chapter 1.0 Introduction
What is clinical engineering?
The role of clinical engineering within the hospital organization
Major functions of a clinical engineering department
Professional status of clinical engineering
Future of clinical engineering
References
Section Two Modeling biosystems
Chapter 2.1a Modeling biosystems
2.1a.a Biomedical engineering
2.1a.2 Fundamental aspects of BME
2.1a.3 Constructing engineering models
2.1a.4 Examples of solving BME models by computer
2.1a.5 Overview of the text
2.1a.6 Lessons learned in this chapter
2.1a.7 Problems
References
Chapter 2.1b Introduction to computing
2.1b.1 Introduction
2.1b.2 The role of computers in biomedical engineering
2.1b.3 Programming language tools and techniques
2.1b.4 Fundamentals of data structures for MATLAB
Chapter 2.2 Simulation and estimation
2.2.1 Numerical modeling of bioengineering systems
2.2.2 PhysioNet, PhysioBank, and PhysioToolkit
2.2.3 Signal processing: EEG data
2.2.4 Diabetes and insulin regulation
2.2.5 Renal clearance
2.2.6 Correspondence problems and motion estimation
2.2.7 PHYSBE Simulations
References
Web site links
Chapter 2.3 Signals and systems
2.3.1 Biological systems
2.3.2 Biosignals
2.3.3 Linear signal analysis: overview
2.3.4 Noise and variability
2.3.5 Summary
Chapter 2.4 Basic signal processing
2.4.1 Basic signals: the sinusoidal waveform
2.4.2 Signal properties: basic measurements
2.4.3 Advanced measurements: correlations and covariances
2.4.4 MATLAB implementation
2.4.5 Summary
Section Three Biomaterials science
Chapter 3.1 Properties of materials
3.1.1 Introduction: the solid state
3.1.2 Bulk propertiesof materials
3.1.3 Finite element analysis
3.1.4 Surface propertiesand surface characterizationof materials
3.1.5 Role of waterin biomaterials
Chapter 3.2 Classes of materials used in medicine
3.2.1 Introduction
3.2.2 Polymers
3.2.3 Silicone biomaterials:history and chemistry
3.2.4 Medical fibersand biotextiles
3.2.5 Hydrogels
3.2.6 Applications of ''smartpolymers'' as biomaterials
3.2.7 Bioresorbableand bioerodible materials
3.2.8 Natural materials
3.2.9 Metals
3.2.10 Ceramics, glasses,and glass-ceramics
3.2.11 Pyrolytic carbon forlong-term medical implants
3.2.12 Composites
3.2.13 Nonfouling surfaces
3.2.14 Physicochemical surfacemodification of materials usedin medicine
3.2.15 Textured and porousmaterials
3.2.16 Surface-immobilizedbiomolecules
Section Four Clinical engineering
Chapter 4.1 Clinical applications of bioelectricity
4.1.1 Electrocardiography
4.1.2 Impedance plethysmography
4.1.3 Impedance cardiography
4.1.4 Tissue characterization innbspurology
4.1.5 EEG, ENG/ERG/EOG
4.16 Electrogastrography
4.1.7 EMG and neurography
4.1.8 Electrical impedance myography
4.1.9 Electrotherapy
4.1.10 Body composition analysis
4.1.11 Implanted active thoracic devices
4.1.12 Defibrillation andnbspelectroshock
4.1.13 Electrosurgery
4.1.14 Cell suspensions
4.1.15 Skin instrumentation
4.1.16 Non-medical applications
4.1.17 Electrical safety
Chapter 4.2 Intensive care facilities
Monitoring and diagnostics
Information collection and clinical information systems
Interpretation
Therapy
Clinical engineering and the ICU
References
Further information
Chapter 4.3 Operating theatre facilities
The role of the operating room
Operating room floor plan
Operating room facility infrastructure
Common operating room technologies
Specialized operating room technologies
Safety in the operating room
Conclusion
References
Chapter 4.4 Anesthesiology
What is anesthesia?
Where is anesthesia performed?
Safety concerns
Infrastructure
Airway management tools
Anesthesia machines
Gas mixing
Vaporizers
Breathing circuits
Ventilators
Monitoring
Capnometry and agent analysis
References
Chapter 4.5 Simulation facility design
4.5.1 The virtual hospital - a virtual fantasy?
4.5.2 Design and build for the actual use
4.5.3 The center design team
4.5.4 Simulation center design considerations
4.5.5 Function and utilization
4.5.6 Space by design
4.5.7 Utilities
4.5.8 A walk-through
4.5.9 Conclusion
Section Five Medical devices and instrumentation
Chapter 5.1 Evolution of medical device technology
The origins
Understanding the physical world
The future
Further information
Chapter 5.2 Medical device design and control in the hospital
Design and modification of medical devices in the hospital
Ensuring medical device safety by clinical engineering
Ensuring efficacy and effectiveness
Anticipating future needs during selection
Criteria for involvement
Redesigning or customizing medical devices
Documenting
Product improvements
Conclusion
Acknowledgment
References
Chapter 5.3 - Medical device research and design
From inventor to innovator
The innovator as a person
The life cycle of a product
Strategic assessments for effective product development
Concept testing
Prototype development
Forms of exploitation
References
Further information
Ch5.4-P374646
Chapter 5.4 Medical device software development
Design alternatives and tradeoffs
Software architecture
Choosing a methodology
Choosing a language
Software risk analysis
Software metrics
Requirements traceability
Software reviews
Performance predictability and design simulation
Coding
Design support tools
Design as the basis for verification and validation
Verification and validation life cycle
Verification and validation overview
Test development
Test execution and reporting
Test reports
Further information
Chapter 5.5 Virtual instrumentation
Background
Case study #1: a real-time bed-management and census-control dashboard
Case study #2: PIVITtrade-performancenbspindicator virtual instrument toolkit
Case study #3: BioBench-a virtual instrument application for data acquisition and analysis of physiological signals
Case study #4: a cardiovascular pressure-dimension analysis system
Summary
Reference
Further information
Chapter 5.6 Electromagnetic interference in the hospital
Electromagnetic radiation
Controlling the effect of EMI
Case histories
Variability: a demonstration of the problem
Programs and procedures
Summary
References
Section 6 Medical imaging technology
Chapter 6.1 Fundamentals of magnetic resonance imaging
6.1.1 Early history of nuclear magnetic resonance
6.1.2 General review of MRI
6.1.3 detailed overview ofnbspMRI
6.1.4 MRI hardware design
6.1.5 Pulsing and NMR imaging
References
Chapter 6.2 Optical sensors
6.2.1 Charge -coupled devices
6.2.2 Optical fiber
6.2.3 Analysis of optical fibers
6.2.4 The graded-index fiber
6.2.5 CT scanners in medicine
6.2.6 The endoscope
6.2.7 Digital x rays
6.2.8 Medical sensors from fibernbspoptics
References
Chapter 6.3 Fundamental enhancement techniques
6.3.1 Introduction
6.3.2 Preliminaries and definitions
6.3.3 Pixel operations
6.3 .4 Local operators
6.3.5 Operations with multiple images
6.3.6 Frequency domain techniques
6.3.7 Concluding remarks
Acknowledgments
References
Chapter 6.4 Fundamentals of image segmentation
6.4.1 uction
6.4.2 Thresholding
6.4.3 Region growing
6.4.4 Watershed algorithm
6.4.5 Edge-based segmentation techniques
6.4.6 Multispectral techniques
6.4.7 Other techniques
6.4.8 Concluding remarks
References
Ch6.5-P374646
Chapter 6.5 Registration for image-guided surgery
6.5.1 Introduction
6.5.2 Image-guided neurosurgery system
6.5.3 Operating room procedure
6.5.4 Performance analysis
6.5.5 Operating room results
6.5.6 Summary
References
Chapter 6.6 Visualization pathways innbspbiomedicine
6.6.1 Visualization in medicine
6.6.2 Illustrative visualization
6.6.3 Investigative visualization
6.6.4 Imitative visualization
6.6.5 Visualization in biology
6.6.7 Visualization in spatial biostatistics
6.6.8 Parametric visualization
Section 7 Tissue engineering
Chapter 7.1 Tissue engineering
7.1.1 Introduction
7.1.2 Overview of tissueengineering
7.1.3 Immunoisolation
7.1.4 Synthetic bioresorbablepolymer scaffolds
Chapter 7.2 Scope of tissue engineering
7.2.1 Functions of scaffold
7.2.2 Absorbable biomaterials
7.2.3 Pore creation in biomaterials
7.2.4 S pecial scaffolds
7.2.5 Surface modifications
7.2.6 Cell expansion and differentiation
7.2.7 Growth factors
7.2.8 Cell sources
References
Note added in proof
Section 8 Ethics in biomedical engineering
Chapter 8.1 Bioethics: a creative approach
Thought experiments
The principle of double effect
Credat emptor
The good engineer
Feedback and enhancement of design
Engineering bioethics and morality
''Small'' error and devastating outcomes
Technology, engineering, and economics
Engineering competence
Engineering: both integrated and specialized
Who is a professional?
What is technical?
Systematics: incorporating ethics into the design process
Notes and commentary
Chapter 8.2 Bioethics and the engineer
Major bioethical areas
Cloning and stem cell research
Human enhancement
Patenting life
Neuroethics
Organ transplantation
Responsible conduct of human research
Animal testing
Genetically modified organisms
Environmental health: the ethics ofnbspscalenbspand the scale of ethics
Temporal aspects of bioethical decisions: environmental case studies
Scale is more than size
Active engineering
Ethical theories: a primer
Notes and commentary
Index
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Biomedical Engineering e-Mega Reference

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