Correlation Force Spectroscopy for Single Molecule Measurements
1st Edition
Published on 30. March 2015
XXVII, 117 pages
978-3-319-14048-3 (ISBN)
Description
This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm
3
) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.
More details
Series
Language
English
Place of publication
Cham
Switzerland
Publishing group
Springer International Publishing
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
XXVII, 117 p. 48 illus., 31 illus. in color.
File size
5,30 MB
ISBN-13
978-3-319-14048-3 (9783319140483)
DOI
10.1007/978-3-319-14048-3
Schweitzer Classification
Other editions
Additional editions
Book
04/2015
Springer
€106.99
Shipment within 10-15 days
Person
Milad Radiom received his PhD in Chemical Engineering at Virginia Tech in 2014, after MEng and BSc in Thermal and Fluids Engineering and Mechanical Engineering respectively from Nanyang Technological University and Amirkabir University of Technology. Thereafter, he was appointed as a postdoctoral research associate in Laboratory of Colloid and Surface Chemistry, University of Geneva. His research interests are physical chemistry of polymers, colloids and surfaces as related to single molecule force spectroscopy, micro-rheology and surface forces.
Content
Introduction.- Correlation Force Spectroscopy.- Dynamics of Single Molecules.- Microrheology with Correlation Force Spectroscopy.- Development of Colloidal Probe Correlation Force Spectroscopy: Case Study.- Correlation Force Spectroscopy for Single Molecule Measurements.- Single Molecule Force Spectroscopy of Dextran.- Single Molecule Force Spectroscopy of Single-Stranded DNA.- Summary.
