The Inhibitor Index
A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads
Published on 20. July 2017
1368 pages
978-1-351-73067-9 (ISBN)
Description
Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a process of interest is functionally linked to a particular enzyme or receptor. From antibiotics to statins, modern medicine relies on the reliability and ease-of-use of enzyme- and receptor-directed inhibitors and antagonists.The Inhibitor Index is a comprehensive, curated compendium of over 7,800 enzyme inhibitors and receptor antagonists, including many toxins, poisons, and metabolic uncouplers.
Reviews / Votes
"Purich has compiled this handy reference tool listing approximately 7,800 biologically significant molecules that inhibit the action of enzymes or block cellular receptors...The list of targets enables laboratory researchers to choose the most specific and selective inhibitors or blockers for their experiments, and to remain alert to off-target effects. This unique desk reference will be useful for advanced undergraduate students, graduate students, and researchers devising laboratory research in cellular biochemistry and new drug development."-CHOICE, February 2018 Vol. 55 No. 6
More details
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
7000 s/w Abbildungen
1 Tables, black and white; 5824 Illustrations, black and white
File size
60,14 MB
ISBN-13
978-1-351-73067-9 (9781351730679)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Daniel Purich
The Inhibitor Index
A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads
Book
06/2017
1st Edition
CRC Press
€308.50
Shipment within 10-20 days
Person
Dan Purich earned his Ph.D. for ground-breaking work on brain hexokinase, adenine nucleotide control, and multisubstrate inhibitors under Herbert Fromm at Iowa State University. After investigating the glutamine synthetase adenylylation cascade as an NIH Staff Fellow under Earl Stadtman, he joined the Chemistry Department at UC Santa Barbara. Awarded a Sloan Fellowship in Chemistry and NIH Research Career Development Award, Purich rose to full professor before moving to the University of Florida College of Medicine to become Chair of Biochemistry & Molecular Biology. He served on the Journal of Biological Chemistry, Archives of Biochemistry & Biophysics, and Biophysical Chemistry editorial boards. He also edited the six-volume Enzyme Kinetics & Mechanism sub-series of Methods in Enzymology and wrote The Handbook of Biochemical Kinetics (2000), The Enzyme Reference (2002), and Enzyme Kinetics: Catalysis & Control (2010). Author of over 170 peer-reviewed papers, chapters and reviews on enzyme action and cytoskeleton self-assembly, Purich discovered the actoclampins, the (+)-end-tracking motors that power actin-based motility by harnessing the Gibbs energy of on-filament ATP hydrolysis, while catalyzing monomer insertion. For fun, he travels and writes mystery novels.
Content
No TOC, it is an alphabetical listing of compounds.
