Progress in Nucleic Acid Research and Molecular Biology
Academic Press
Published on 14. October 1993
276 pages
978-0-08-086334-4 (ISBN)
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Progress in Nucleic Acid Research and Molecular Biology
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10/1993
Academic Press
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Content
- Cover
- Contents
- Abbreviations and Symbols
- Some Articles Planned for Future Volumes
- Chapter 1. Adenoviral DNA Integration and Changes in DNA Methylation Patterns: A Different View of Insertional Mutagenesis
- I. Scope of Review
- II. Survey of Basic Findings on Adenovirus DNA Integration
- III. Uptake of Foreign (Adenoviral) DNA by Mammalian Cells
- IV. On the Mechanism of Adenovirus DNA Integration
- V. De Novo Methylation of Integrated Foreign DNA
- VI. Alterations in Cellular Gene Expression in Adenovirus-Infected and -Transformed Cells
- VII. A Different View of Insertional Mutagenesis
- References
- Chapter 2. Posttranscriptional Control of the Lysogenic Pathway in Bacteriophage Lambda
- I. ? Genes Involved in the Lysis/Lysogeny Decision
- II. RNase III in Posttranscriptional Regulation of ? Genes
- III. Stimulation of cII Translation by IHF
- IV. Metabolic Instability of Phage Regulatory Proteins
- V. Concluding Remarks
- References
- Chapter 3. Global Regulation of Mitochondria1 Biogenesis in Saccharomyces cerevisiae
- I. Transcriptional Regulation and Signal Transduction in Yeast
- II. Transcriptional Regulation by Oxygen
- III. Differential Regulation of Gene Pairs
- IV. Transcriptional Regulation by Carbon Source
- V. Transcriptional Regulation under Stress Conditions
- VI. A Path from Mitochondrion to Nucleus?
- VII. Mitochondrial Biogenesis and the Yeast Cell Cycle
- VIII. Regulation of Mitochondrial Biogenesis in Relation to Cell Growth
- IX. Mitochondrial Biogenesis in Evolutionary Perspective
- X. Conclusions and Prospects
- References
- Chapter 4. DNA Polymerase II, the Epsilon Polymerase of Saccharomyces cerevisiae
- I. Categorization and Nomenclature
- II. DNA Polymerase II Structure and Activities
- III. Cell Cycle Regulation
- IV. Domain Structure of Catalytic Subunit
- V. Genetics of 3'"5' Exonuclease
- VI. The DNA Repair Polymerase
- VII. Role of DNA Polymerase II in DNA Replication
- References
- Chapter 5. Regulation of Bacillus subtilis Gene Expression during the Transition from Exponential Growth to Stationary Phase
- I . The Bacillus subtilis Transition State
- II. Keeping Stationary Phase Gene Expression Off: Transition-State Regulators
- III. Activators and Modulators of Transition-State Gene Expression
- IV. Initiating Sporulation
- V. "Redundant" Control of Transition-State Genes
- VI. Concluding Remarks
- References
- Chapter 6. Genomic Organization of T and W, a New Family of Double-Stranded RNAs from Saccharomyces cerevisiae
- I. General Features
- II. T and W Genomic Organization
- III. Single-Stranded RNA Counterparts of T and W dsRNAs
- IV. Configuration of W and 20-S RNA
- V. T and W Replication Cycles
- VI. T and W Are Not Encapsidated into Viral Particles
- VII. Are the RNA Polymerases Associated with the RNAs?
- VIII. Relationship between T and W and Other Mycoviruses
- IX. Evolutionary Origin of T and W
- X. Conclusions and Perspectives
- References
- Chapter 7. Mechanism of Action and Regulation of Protein Synthesis Initiation Factor 4E: Effects on mRNA Discrimination, Cellular Growth Rate, and Oncogenesis
- I. Regulation of Initiation
- II. mRNA Binding to Ribosomes
- III. Isololation and Structural Characterization of elF-4E
- IV Actives of elF-4E
- V. Regulation of eIF-4E Activity by Phosphorylation
- VI. Alteration of Intracellular Levels of eIF-4E
- VII. Summary, Conclusions, and Future Directions
- References
- Chapter 8. Enzymology of Homologous Recombination in Saccharomyces cerevisiae
- I. Recombination Models
- II. Physical Analysis of Recombination
- III. Enzymology of Homologous Genetic Recombination in S. cereoisiae
- References
- Index
