Progress in Nucleic Acid Research and Molecular Biology
Academic Press
Published on 2. April 1990
285 pages
978-0-08-086326-9 (ISBN)
Description
Progress in Nucleic Acid Research and Molecular Biology
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Waldo E. Cohn | Waldo E. Cohn | Kivie Moldave
Progress in Nucleic Acid Research and Molecular Biology: v. 38
Book
02/1990
Academic Press
€94.87
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Content
- Cover
- Contents
- Abbreviations and Symbols
- Some Articles Planned for Future Volumes
- Chapter 1. Control of Prokaryotic TranslationaI Initiation by mRNA Secondary Structure
- I. mRNA Secondary Structure Reduces the Efficiency of Translational Initiation
- II. The Efficiency of a Ribosome Binding Site Is Linearly Proportional to the Fraction of Unfolded Molecules
- III. Natural Ribosome Binding Sites Have a Low Potential for Secondary Structure Formation
- IV. Secondary Structures Upstream of the Shine-Dalgarno Sequence
- V. Inducible Ribosome Binding Sites
- VI. Regulatory Proteins Functioning through Changes in mRNA Secondary Structure
- VII. Differential Translation from Alternative mRNAs
- VIII. Concluding Remarks on the Mechanism of Translational Initiation
- References
- Chapter 2. Molecular Genetics of Na,K-ATPase
- I. Na,K-ATPase Structure
- II. Structure-Function Relationships of the Cardiac Glycoside Binding Site
- III. Regulation of Na,K-ATPase Expression
- IV. Na,K-ATPase Genes
- V. Summary
- References
- Chapter 3. Retroviral-Mediated Gene Transfer
- I. Methods of Gene Transfer
- II. Retroviral Vectors
- III. Gene Transfer and Expression in Mammalian Cells
- IV. Use of Retroviral Vectors for Human Gene Therapy
- V. Future Prospects
- References
- Chapter 4. Structure-Function Relationships in Escherichiu coli Promoter DNA
- I. RNA Polymerase
- II. Promoter Sequences
- III. Kinetic Analysis of Promoters
- IV. Promoter Structure
- V. Summary and Implications for the Structure of RNA Polymerase
- References
- Chapter 5. Gene Expression in Seed Development and Germination
- I. Overview of Seed Development, Germination, and Seedling Establishment
- II. Protein Synthesis during Seed Development
- III. Gene Expression during Germination and Seedling Establishment
- References
- Chapter 6. Transcriptional and Translational Regulation of Gene Expression in the General Control of Amino-Acid
- I. General Amino-Acid Control in Saccharomyces cerevisiae
- II. trans-Acting Regulatory Factors in General Amino-Acid Control
- III. cis-Acting Regulatory EIenrents in General Amino-Acid Control
- IV. Functional Domains of the GCN4 Protein
- V. Translational Control of GCN4 Expression
- VI. trans-Acting Translational Regulators of GCN4
- VII. Transcriptional Control of GCN4 Expression
- VIII. Conclusions
- References
- Chapter 7. Mechanisms Regulating Transient Expression of Mammalian Cytokine Genes and Cellular Oncogenes
- I. Stimulation of Transient Gene Expression
- II. Time Course and Kinetics of Sequential Gene Expression
- III. Lymphokines as a Distinctive Subset of Cytokines
- IV. Mechanisms Regulating Transient Gene Expression
- V. Transcription of Genes by RNA Polymerase II
- VI. Posttranscriptional Regulation of Cytokine Genes and Cellular Oncogenes
- VII. Concluding Remarks
- References
- Index
