
Progress in Nucleic Acid Research and Molecular Biology
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Content
- Front Cover
- Progress in NucIeic Acid Research and Molecular Biology, Volume 8
- Copyright Page
- Contents
- List of Contributors
- Preface
- Abbreviations and Symbols
- Contents of Previous Volumes
- Some Articles Planned for Future Volumes
- Chapter 1. Nucleic Acids-The First Hundred Years
- Text
- References
- Chapter 2. Nucleic Acids and Protamine in Salmon Testes
- I. Introduction
- II. The Salmons and Spermatogenesis
- III. Deoxyribonucleic Acid
- IV. Ribonucleic Acids
- V. Enzymes Degrading Nucleic Acids
- VI. Protamine
- VII. Nucleoprotamines
- References
- Chapter 3. Experimental Approaches to the Determination of the Nucleotide Sequences of Large Oligonucleotides and Small Nucleic Acids
- I. Introduction
- II. Identification of Ribonuclease Digest Fragments
- III. Determination of the Nucleotide Sequences of Small Nucleic Acids
- IV. Conclusion
- References
- Chapter 4. Alterations of DNA Base Composition in Bacteria
- I. Introduction
- II. Mutants with High and low G + C Content in Gramd-Negative Bacteria
- III. Mutants with High and Low G + C Content in Spore-Forming Bacilli
- IV. Mutants with High G + C Content in Gram-Positive Cocci
- V. Strains with Low G + C Content in Actinomycetes
- VI. Discussion
- References
- Chapter 5. Chemistry of Guanine and Its Biologically Significant Derivatives
- I. Introduction
- II. Naturally Occurring Guanine Derivatives
- III. Physical Properties
- IV. Chemical Properties
- V. Conclusion
- References
- Chapter 6. Bacteriophage FX174 and Related Viruses
- I. Introduction
- II. The Viral Strains
- III. The Virus Particle
- IV. The Infective Process
- V. Conclusion
- References
- Note Added in Proof
- Chapter 7. The Preparation and Characterization of Large Oligoribonucleotides
- I. Introduction
- II. Preparation of Homogeneous RNA
- III. Methods for Preparation of Large Oligonucleotides
- IV. Characterization of Large Oligonucleotides
- V. Fractionation of Large Oligonucleotides
- VI. Prospects
- References
- Chapter 8. Purine N-Oxides and Cancer
- I. Introduction
- II. N-Oxidations of Purines
- III. Other Syntheses of Purine N-Oxides
- IV. Rearrangements and Ring Openings
- V. Absorption Spectra of Purine N-Oxides
- VI. Photochemical Reactions of Purine N-Oxides
- VII. Natural Occurrence and Metabolism of N-Oxides
- VIII. Purine-N-Oxides as Antimetabolites
- IX. Purine N-Oxides as Oncogenic Agents
- X. The Relation of Purine N-Oxides to Other N-Containing Oncogens
- XI. Speculation
- References
- Note Added in Proof
- Chapter 9. The Photochemistry, Photobiology, and Repair of Polynucleotides
- I. Introduction
- II . Photoproducts in Polynucleotides
- III. The Action of Enzymes on Irradiated Polynucleotides
- IV. The Biological Activity of Ultraviolet-Irradiated DNA
- V. Cells and Viruses
- VI. Steps in the Repair of DNA
- VII. Conclusion
- References
- Note Added in Proof
- Chapter 10. What Really is DNA? Remarks on the Changing Aspects of a Scientific Concept
- I. Introduction
- II. Formulation
- III. Oversimplification
- IV. Anarchy
- V. The Current Scene
- VI. A Modest Glimpse of the Future
- VII. Epilogue
- References
- Chapter 11. Recent Nucleic Acid Research in China
- I. Introduction
- II. Highlights of Research
- III. Conclusions
- References
- Author Index
- Subject Index
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