Progress in Medicinal Chemistry
Elsevier (Publisher)
Published on 9. April 2018
366 pages
978-0-444-64144-1 (ISBN)
Description
Progress in Medicinal Chemistry, Volume 57, provides a review of eclectic developments in medicinal chemistry, with this volume including chapters on the CaSR field, CFTR modulators in cystic fibrosis, macrocycles, VMAT2 inhibitors, and Big Data in Drug Discovery.
- Provides extended, timely reviews of topics in medicinal chemistry
- Contains targets and technologies relevant to the discovery of tomorrow's drugs
- Presents analyses of successful drug discovery programs
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1. Discovery and Development of Calcimimetic and Calcilytic CompoundsEdward F. Nemeth, Bradford C. Van Wagenen and Manuel F. Balandrin2. VMAT2 Inhibitors and the Path to Ingrezza (Valbenazine)Nicole D. Harriott, John P. Williams, Evan B. Smith, Haig P. Bozigian and Dimitri E. Grigoriadis3. Current Trends in Macrocyclic Drug Discovery and Beyond-Ro5Sulejman Alihodzic, Mirjana Bukvic, Ivaylo J. Elenkov, Antun Hutinec, Sanja KoStrun, Dijana Pesic, Gordon Saxty, Linda TomaSkovic and Dinko Ziher4. Recent Progress in the Discovery and Development of Small-Molecule Modulators of CFTRPhil R. Kym, Xueqing Wang, Mathieu Pizzonero and Steven E. Van der Plas5. Big Data in Drug DiscoveryNathan Brown, Jean Cambruzzi, Peter J. Cox, Mark Davies, James Dunbar, Dean Plumbley, Matthew A. Sellwood, Aaron Sim, Bryn I. Williams-Jones, Magdalena Zwierzyna and David W. Sheppard
