Progress in Medicinal Chemistry
Elsevier (Publisher)
Published on 2. March 1992
349 pages
978-0-08-086277-4 (ISBN)
Description
The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT 3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey of the herb feverfew. The volume concludes, as it began, with enzyme inhibition - in this case concerning synthetic inhibitors of interstitial collagenases.
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D. K. Luscombe | Gwynn P. Ellis | Geoffrey Buckle West
Progress in Medicinal Chemistry: v.29
Book
03/1992
Elsevier
€170.84
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Content
- Front Cover
- Progress in Medicinal Chemistry, Volume 29
- Copyright Page
- Contents
- Preface
- Chapter 1. 5-Lipoxygenase Inhibitors and their Anti-inflammatory Activities
- Chapter 2. An Overview of Class III Electrophysiological Agents: A New Generation of Antiarrhythmic Therapy
- Chapter 3. Chemical Structures and Biological Activities of Non-Peptide Selective Kappa Opioid Ligands
- Chapter 4. Pharmacologically Active Pyridazine Derivatives. Part 2
- Chapter 5. Centrally Acting Dopamine D2 Receptor Ligands: Agonists
- Chapter 6. Progress in the Medicinal Chemistry of the Herb Feverfew
- Chapter 7. Ondansetron and Related 5-HT3 Antagonists: Recent Advances
- Chapter 8. Synthetic Inhibitors of Bacterial and Mammalian Interstitial Collagenases
- Index
- Author Index (Vols. 1-29)
- Subject Index (Vols. 1-29)
