Progress in Medicinal Chemistry
Butterworth-Heinemann (Publisher)
Published on 22. September 2011
371 pages
978-0-08-086254-5 (ISBN)
Description
Progress in Medicinal Chemistry
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Content
- Front Cover
- Progress in Medicinal Chemistry, Volume 6
- Copyright Page
- Contents
- Preface
- CHAPTER 1. THE BRITISH PHARMACOPOEIA COMMISSION
- Historical introduction
- Post-war developments
- Legal position of the Pharmacopoeia
- Reference substances
- Approved names
- Future developments
- CHAPTER 2. PHARMACOLOGICAL ASPECTS OF THE CORONARY CIRCULATION
- Introduction
- Clinical implications
- Physiological determinants of coronary flow
- Mechanisms through which drugs modify coronary flow
- Methods of evaluating the action of drugs on the coronary circulation
- Naturally occurring substances that modify coronary flow
- Drugs used in the treatment of angina pectoris
- Conclusions
- CHAPTER 3. SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST-PART I
- Introduction
- 2,4-Diaminopyrimidines and related compounds
- Halogenated pyrimidines
- Sulphur-substituted pyrimidines
- 2-Substituted 4-amino-5-hydroxymethylpyrimidine and related compounds
- Pyrimidine sulphonamides
- Pyrimidine and condensed pyrimidine antibiotics
- CHAPTER 4. THE MECHANISM OF ACTION OF SOME ANTIBACTERIAL AGENTS
- Introduction
- Antibacterial agents and bacterial cell walls
- Antibacterial agents and cytoplasmic membranes
- Substances inhibiting protein and nucleic acid syntheses
- Metal-binding and antibacterial action
- Addendum
- CHAPTER 5. THE BIOSYNTHESIS AND METABOLISM OF THE CATECHOLAMINES
- Historical introduction
- Catecholamine biosynthesis
- D-DOPA and D-amino acid oxidase
- L-DOPA
- Dopamine
- Noradrenaline and adrenaline
- Enzymes responsible for catecholamine biosynthesis
- Metabolism of catecholamines
- Enzymes involved in metabolism of catecholamines
- CHAPTER 6. THE LITERATURE OF MEDICINAL CHEMIS'IRY
- Introduction
- General textbooks and monographs
- Relationship between chemical structure and biological activity (including receptor sites, stereochemical aspects)
- Spectroscopic and other analytical techniques
- Radiochemical and radiobiological topics
- Alkaloids
- Amino acids, peptides and proteins
- Carbohydrates of medicinal interest
- Enzymes and enzyme inhibitors
- Heterocyclic compounds of medicinal interest
- Hormones and prostaglandins
- Lipids and atherosclerosis
- Metals and their chelates
- Nucleosides, nucleotides and nucleic acids
- Phosphorylated compounds
- Steroids
- Various organic chemical groups of medicinal interest
- Vitamins
- Transport and metabolism of drugs
- Drugs and the central nervous system
- Local anaesthetic drugs
- Antitussive drugs
- Drugs and the peripheral nervous system
- Histamine, 5-hydroxytryptamine and their antagonists
- Non-steroidal anti-inflammatory drugs
- Immunochemistry and allergy
- Hypoglycaemic drugs
- Diuretic and antidiuretic drugs
- Blood and cardiovascular disorders
- Anticancer agents
- Psychopharmacological drugs
- Chemotherapy
- Uricosuric drugs
- Radiopaque agents
- Patenting of drugs
- Miscellaneous topics
- Addendum
- Index
