Progress in Medicinal Chemistry
Butterworth-Heinemann (Publisher)
Published on 1. January 1965
220 pages
978-0-08-086252-1 (ISBN)
Description
Progress in Medicinal Chemistry
More details
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Content
- Front Cover
- Progress in Medicinal Chemistry, Volume 4
- Copyright Page
- Contents
- Preface
- Chapter 1. Experimental Hypersensitivity Reactions
- Introduction
- Studies on histamine
- Studies on 5-hydroxytryptamine
- Studies on bradykinin
- The anaphylactoid reaction
- Influence of the adrenal gland
- Influence of the thyroid gland
- Influence of insulin
- Discussion
- Chapter 2. Mechanisms of Toxic Action
- Introduction
- Biochemical basis of some toxic actions
- Interpretation of biochemical disturbances
- Research into toxic mechanisms
- General aspects of drug toxicity
- Conclusions
- Chapter 3. Drug Receptor Interactions
- Introduction
- The drug
- The receptor
- Drug receptor interactions: the forces
- Drug receptor interactions: the consequences
- Chapter 4. Polypeptides of Medicinal Interest
- Introduction
- Techniques of Peptide chemistry
- Methods of structural elucidation
- Methods of peptide synthesis
- Polypeptides
- Method of presentation
- Oxytocin and vasopressin
- Corticotropin and the melanocyte-stimulating hormones
- Angiotensin
- Bradykinin and kallidin
- Insulin and glucagon
- Chapter 5. Analgesics and Their Antagonists: Biochemical Aspects and Structure-Activity Relationships
- Estimation of analgesics in biological media
- Absorption, distribution and excretion of analgesics
- Metabolism of analgesics
- Antagonists of analgesics
- Relation of morphine-type analgesics to adrenergic and cholinergic mechanisms and other biochemical processes
- Structure-activity relationships
- Index
