Progress in Medicinal Chemistry
Butterworth-Heinemann (Publisher)
Published on 22. September 2011
200 pages
978-0-08-086250-7 (ISBN)
Description
Progress in Medicinal Chemistry
More details
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Content
- Front Cover
- Progress in Medicinal Chemistry 2
- Copyright Page
- Contents
- Preface
- CHAPTER 1. THE PATENTING OF DRUGS
- Introduction
- Patentable inventions
- Procedure for securing a United Kingdom patent
- Procedures for securing an overseas patent
- The specification
- The inventor
- Scope of the monopoly
- Selection inventions
- The patent after grant
- CHAPTER 2. THE TESTING AND DEVELOPMENT OF ANALGESIC DRUGS
- Introduction
- Tests for analgesic activity
- Classes of analgesic drugs
- Conclusions
- CHAPTER 3. MECHANISMS OF NEUROMUSCULAR BLOCKADE
- Introduction
- Resting potential and action potential in nerve and muscle
- Neuromuscular transmission
- Methods of producing neuromuscular block
- Screening of neuromuscular blocking agents
- Clinically useful neuromuscular blocking agents
- CHAPTER 4. 2-HALOGENOALKYLAMINES
- Introduction
- Dibenamine
- Pharmacological actions of 2-halogenoalkylamines
- Chemistry of 2-halogenoalkylamines
- Pharmacological activity and chemical reactivity in 2-halogenoalkylamines
- Stability of 2-halogenoalkylamines
- Mode of action of 2-halogenoalkylamines
- Interaction with amines
- Therapeutic uses of 2-halogenoalkylamines
- Conclusion
- CHAPTER 5. ANAPHYLACTIC REACTIONS
- Introduction
- Definitions
- Antigen-antibody combination
- Delayed hypersensitivity
- Types of anaphylaxis
- Anaphylaxis in different species
- Methods of producing anaphylaxis
- Mechanisms of anaphylaxis
- Inhibition of anaphylaxis
- Allergy in man
- Index
