
Operative Standards for Cancer Surgery
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Content
- Intro
- LIST OF CONTRIBUTORS
- FOREWORD
- PREFACE
- METHODOLOGY RESEARCH PROTOCOL
- SUMMARY OF CRITICAL ELEMENTS AND RECOMMENDATIONS
- SECTION I THYROID
- Introduction
- Clinical Staging
- Multidisciplinary Care
- Perioperative Care
- Physical Examination and Biochemical Evaluation
- Preoperative Imaging
- Cervical Ultrasonography
- Computed Tomography and Magnetic Resonance Imaging
- REFERENCES
- Chapter 1: Thyroidectomy
- CRITICAL ELEMENTS
- 1. COMPLETE EXTRACAPSULAR DISSECTION OF THE THYROID
- Rationale
- 2. IDENTIFICATION AND PRESERVATION OF THE PARATHYROID GLANDS
- Rationale
- 3. IDENTIFICATION AND PRESERVATION OF THE RECURRENT LARYNGEAL NERVES
- Rationale
- 4. EN BLOC RESECTION OF LOCALLY ADVANCED THYROID CANCER
- Rationale
- Strap Muscles
- Recurrent Laryngeal Nerve
- Trachea
- Esophagus
- Key Question: Oncologic Components of Thyroidectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- SUMMARY
- CONCLUSIONS
- Chapter 2: Oncologic Components of Lymphadenectomy
- CRITICAL ELEMENTS
- 1. RESECTION OF LYMPH NODES IN THE CENTRAL COMPARTMENT
- Rationale
- Technical Aspects
- 2. MANAGEMENT OF THE RECURRENT LARYNGEAL NERVE WHEN INVOLVED BY EXTRANODAL EXTENSION FROM LYMPH NODE METASTASES
- Rationale
- Technical Aspects
- 3. MANAGEMENT OF CLINICALLY POSITIVE LYMPH NODES IN THE LATERAL NECK
- Rationale
- Technical Aspects
- 4. MANAGEMENT OF EXTRANODAL EXTENSION IN THE LATERAL NECK
- Rationale
- Technical Aspects
- Key Question: Oncologic Components of Lymphadenectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- SUMMARY
- CONCLUSION
- REFERENCES
- SECTION II GASTRIC
- Introduction
- Staging
- Pretreatment Staging
- Quality Metrics
- Surgery for Gastric Adenocarcinoma
- Objectives
- REFERENCES
- Chapter 3: Gastrectomy
- CRITICAL ELEMENTS
- 1. INTRAOPERATIVE STAGING
- Rationale
- Staging Laparoscopy
- Timing of Staging Laparoscopy
- Technical Aspects
- 2. RESECTION OF PRIMARY TUMOR
- 2A. Endoscopic Resection
- Rationale
- Indications for Endoscopic Resection
- Identifying EGC Lesions Suitable for Endoscopic Resection
- Technical Aspects
- Endoscopic Mucosal Resection
- Endoscopic Submucosal Dissection
- Comparison of EMR and ESD in the Treatment of EGC
- Comparison of Endoscopic Resection and Gastrectomy for EGC
- 2B. Partial and Total Gastrectomy
- Rationale
- Formal Gastrectomy
- Bursectomy
- Resection of Adjacent Organs and Structures
- Technical Aspects
- CONCLUSION
- 2C. Minimally Invasive Gastrectomy
- Rationale
- Minimally Invasive Distal Gastrectomy
- Technical Aspects of Minimally Invasive Distal and Subtotal Gastrectomy
- Advanced Gastric Cancer and Minimally Invasive Gastrectomy
- Technical Aspects of Minimally Invasive Total Gastrectomy
- Robotic Gastrectomy
- CONCLUSION
- 3. ASSESSMENT OF SURGICAL MARGINS
- Rationale
- Margin Distance
- Distal Tumors of the Body and Antrum: Proximal Margin Length
- Proximal Tumors of the Gastroesophageal Junction, Cardia, and Fundus: Proximal Margin Length
- Frozen-Section Margin Analysis
- The Distal Resection Margin
- Clinical Context, Outcomes, and Management of Positive Margins
- 4. REGIONAL LYMPHADENECTOMY
- INTRODUCTION
- Evolution of the Definitions and Classifications of Lymph Node Stations and Lymphadenectomy
- Rationale for the Boundaries of Systematic Lymphadenectomy
- Extent of Dissection and Adequacy of Staging
- Lymph Node Retrieval and Recommended Lymph Node Counts
- Technical Considerations
- 5. RECONSTRUCTION OF THE GASTROINTESTINAL TRACT
- 5A. After Total Gastrectomy
- Rationale
- Roux-en-Y With or Without Jejunal Pouch
- Bowel Interposition
- 5B. After Distal and Subtotal Gastrectomy
- Rationale
- Roux-en-Y Versus Billroth I Reconstruction
- Roux-en-Y Versus Billroth II Reconstruction
- 5C. After Proximal Gastrectomy
- Rationale
- 6. PLACEMENT OF DRAINS AND TUBES
- 6A. Placement of Intraperitoneal Drain
- Rationale
- 6B. PLACEMENT OF SMALL-BOWEL FEEDING TUBE
- Rationale
- Key Question: Gastrectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- D1 Versus D2 Lymphadenectomy
- Role of Splenectomy
- Learning Curve for D2 Gastrectomy
- The Role of Adjuvant Treatment after D1/D2 Lymphadenectomy
- D1/D2 Versus D3/D4 Para-aortic Lymph Node Dissection
- CONCLUSIONS
- Key Question: Gastrectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Margins
- Lymph Node Harvest
- Survival/Outcomes
- Postoperative Morbidity
- Proximal Versus Total Gastrectomy
- CONCLUSIONS
- REFERENCES
- SECTION III RECTUM
- Introduction
- Anatomy
- Clinical and Pathological Staging
- Multidisciplinary Care
- Perioperative Care
- Quality Metrics
- Summary
- REFERENCES
- Chapter 4: Proctectomy
- CRITICAL ELEMENTS
- 1. PROXIMAL VASCULAR LIGATION
- Rationale
- Technical Aspects
- 2. TOTAL MESORECTAL EXCISION
- Rationale
- Technical Aspects
- 3. LYMPH NODE DISSECTION
- Rationale
- 4. CLEARANCE OF THE DISTAL MARGIN
- Rationale
- Technical Aspects
- Chapter 5: Abdominoperineal Resection
- CRITICAL ELEMENTS
- 1. CLEARANCE OF THE CIRCUMFERENTIAL MARGIN AT THE PELVIC FLOOR
- Rationale
- Technical Aspects
- Lithotomy Versus Prone
- 2. RECONSTRUCTION OF THE PERINEUM
- Rationale
- Technical Aspects
- Key Question: Proctectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Surgical Techniques and Differences in Outcomes
- Local Recurrence Rates and Overall Survival
- CONCLUSION
- Chapter 6: Local Excision
- CRITICAL ELEMENTS
- 1. COMPLETE RESECTION OF AN INTACT SPECIMEN WITH NEGATIVE BOWEL WALL AND DEEP MARGINS
- Rationale
- Key Question: Local Excision
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Surgical Techniques and Outcomes
- Functional Outcomes
- Overall Survival Rates
- CONCLUSION
- REFERENCES
- SECTION IV ESOPHAGUS
- Introduction
- Diagnosis and Clinical Staging
- Multidisciplinary Care
- Perioperative Care
- Quality Metrics
- REFERENCES
- Chapter 7: Esophagectomy
- CRITICAL ELEMENTS
- 1. RESECTION OF THE PRIMARY TUMOR TO NEGATIVE MARGINS
- Rationale
- Proximal Margin
- Distal (Gastric) Margin
- Circumferential (Radial) Margin
- Technical Aspects
- 2. LYMPH NODE DISSECTION
- Rationale
- Technical Aspects
- Abdominal Field
- Mediastinal/Thoracic Field
- Cervical Field
- 3. GASTROINTESTINAL RECONSTRUCTION
- 3A. CONSTRUCTION OF GASTRIC CONDUIT
- Rationale
- Vascular Anatomy of the Gastric Conduit
- 3B. PERFORMANCE OF A GASTRIC-EMPTYING PROCEDURE
- Rationale
- Technical Aspects
- Pyloromyotomy
- Pyloroplasty
- SUMMARY
- 3C. ALTERNATE CONDUITS
- Rationale
- Technical Aspects: Colon
- Technical Aspects: Jejunum
- 3D. CERVICAL VERSUS INTRATHORACIC ANASTOMOSIS
- Rationale
- 3E. HAND-SEWN VERSUS STAPLED ANASTOMOSIS
- Rationale
- 3F. END-TO-END VERSUS END-TO-SIDE ANASTOMOSIS
- Rationale
- Technical Aspects
- Key Question: Esophagectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Recommended Staging of T1a and T1b Adenocarcinoma
- Definition and Brief Description of Endoscopic Eradication Therapy
- FINDINGS
- T1aN0 Esophageal Adenocarcinoma
- cT1b Esophageal Adenocarcinoma
- Endoscopic Eradication Therapy Versus Esophagectomy for T1N0 Unspecified Disease
- Key Question: Esophagectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Ensuring Adequacy of Lymphadenectomy
- Effect of the Histology of the Cancer on the Need for Lymphadenectomy
- Effect of the Pathologist
- Induction Chemoradiotherapy and Lymph Node Yield
- Key Question: Esophagectomy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Perioperative Chemotherapy and Surgery Versus Surgery Alone
- Neoadjuvant Chemoradiotherapy Versus Surgery Alone
- Chemotherapy Versus Chemoradiotherapy before Surgery
- Definitive Chemoradiotherapy Versus Chemoradiotherapy Plus Surgery
- CONCLUSIONS
- Key Question: Esophagectomy
- INTRODUCTION
- METHODOLOGY
- Criteria for Evidence
- Search and Analysis
- Results
- FINDINGS
- Five-Year Overall Survival
- Five-Year Relapse-Free Survival
- R0 Resection
- Quality of Life
- Anastomotic Leaks
- Perioperative Mortality
- Complications and Toxicity
- Accuracy of Clinical Staging of T2N0 Esophageal Tumors
- Adenocarcinoma Versus Squamous Cell Carcinoma
- REFERENCES
- SECTION V MELANOMA
- Introduction
- Clinical Staging
- Multidisciplinary Care
- Perioperative Care
- Quality Metrics
- REFERENCES
- Chapter 8: Wide Local Excision
- CRITICAL ELEMENTS
- 1. MARGIN WIDTH
- Rationale
- 2. DEPTH OF EXCISION
- Rationale
- 3. ANATOMIC ORIENTATION OF THE EXCISION
- Rationale
- Chapter 9: Sentinel Lymph Node Biopsy
- CRITICAL ELEMENTS
- 1. DYNAMIC LYMPHOSCINTIGRAPHY TO IDENTIFY THE SENTINEL LYMPH NODE-CONTAINING NODAL BASIN
- Rationale
- Technical Aspects
- 2. PLACEMENT OF THE SENTINEL LYMPH NODE BIOPSY INCISION
- Rationale
- 3. IDENTIFICATION AND REMOVAL OF ONE OR MORE SENTINEL LYMPH NODES
- Rationale
- Technical Aspects
- Key Question: Sentinel Lymph Node Biopsy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- Thin Melanomas
- Thick Melanomas
- Older Patients and Medical Comorbidities
- Prior Wide Local Excision of the Primary Tumor Site
- In-Transit Disease
- CONCLUSION
- Key Question: Sentinel Lymph Node Biopsy
- INTRODUCTION
- METHODOLOGY
- FINDINGS
- FINDINGS
- Sentinel Lymph Node Biopsy with Completion Lymph Node Dissection for Nodal Basin Control
- Sentinel Lymph Node Biopsy with Completion Lymph Node Dissection for Prognostication
- Predicting Nonsentinel Node Positivity
- The Morbidity of Completion Lymph Node Dissection
- CONCLUSION
- Chapter 10: Neck, Axillary, Ilioinguinal, and Other Lymph Node Dissections
- NECK LYMPH NODE DISSECTION
- CRITICAL ELEMENTS
- 1. BOUNDARIES OF AN ONCOLOGICALLY APPROPRIATE NECK DISSECTION
- Rationale
- 2. SUPERFICIAL OR TOTAL PAROTIDECTOMY
- Rationale
- 3. REMOVAL OF A SUFFICIENT NUMBER OF LYMPH NODES FOR ADEQUATE STAGING
- Rationale
- AXILLARY LYMPH NODE DISSECTION
- CRITICAL ELEMENTS
- 1. REMOVAL OF LEVEL I, II, AND III LYMPH NODES
- Rationale
- Technical Aspects
- 2. REMOVAL OF A SUFFICIENT NUMBER OF LYMPH NODES FOR AXILLARY STAGING
- Rationale
- ILIOINGUINAL LYMPH NODE DISSECTION
- CRITICAL ELEMENTS
- 1. RESECTION OF SUPERFICIAL GROIN LYMPH NODES
- Rationale
- Technical Aspects
- 2. REMOVAL OF A SUFFICIENT NUMBER OF LYMPH NODES FOR INGUINAL STAGING
- Rationale
- 3. RESECTION OF DEEP GROIN LYMPH NODES
- Rationale
- Technical Aspects
- 4. SARTORIUS MUSCLE ROTATION FLAP
- Rationale
- Technical Aspects
- 5. MINIMALLY INVASIVE GROIN DISSECTION
- Rationale
- Technical Aspects
- EPITROCHLEAR LYMPH NODE DISSECTION
- CRITICAL ELEMENTS
- 1. INCISION PLACEMENT
- Rationale
- 2. BOUNDARIES OF AN EPITROCHLEAR LYMPHADENECTOMY
- Rationale
- 3. IDENTIFICATION AND PRESERVATION OF THE MEDIAN NERVE AND BRACHIAL ARTERY
- Rationale
- POPLITEAL LYMPH NODE DISSECTION
- CRITICAL ELEMENTS
- 1. INCISION PLACEMENT
- Rationale
- 2. BOUNDARIES OF A POPLITEAL LYMPHADENECTOMY
- Rationale
- 3. IDENTIFICATION AND PRESERVATION OF THE TIBIAL/COMMON PERONEAL NERVES AND THE POPLITEAL VESSELS
- Rationale
- REFERENCES
- Index
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