Prion Protein
Academic Press
Published on 22. August 2017
516 pages
978-0-12-811227-4 (ISBN)
Description
Prion Protein, Volume 150, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on Prion Protein, a protein that is considered to be the archetype of intrinsically disordered proteins. This updated volume includes comprehensive sections on a variety of timely topics, including Functions of Prion Protein, Copper and Prion protein, Cell Biology of Prion Protein, Structural Studies of Prion Proteins, Molecular Simulations on Wild Type and Mutant Prion Proteins, Genetics of Prion Protein, The Prion Concept and Synthetic Prions, and Transgenic Mouse Models.
As neurodegenerative diseases represent a health issue that is receiving increasing attention from the scientific community due to their social and economic impact, this series is an ideal resource for the latest research in molecular biology and translational science.
- Presents the latest volume in the Progress in Molecular Biology and Translational Science series
- Accessible to students and researcher alike
- Written by leading authorities in the field of prion protein
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Giuseppe Legname | Silvia Vanni
Prion Protein: Volume 150
Book
08/2017
Academic Press
€147.56
Shipment within 15-20 days
Persons
Content
1. Functions of the Prion ProteinThéo Z. Hirsch, Séverine Martin-Lannerée and Sophie Mouillet-Richard2. Copper- and Zinc-Promoted Interdomain Structure in the Prion Protein: A Mechanism for Autoinhibition of the Neurotoxic N-TerminusEric G.B. Evans and Glenn L. Millhauser3. Cell Biology of Prion ProteinDaniela Sarnataro, Anna Pepe and Chiara Zurzolo4. Understanding the Effect of Disease-Related Mutations on Human Prion Protein Structure: Insights From NMR SpectroscopyIvana Biljan, Gregor Ilc and Janez Plavec5. Structural Modeling of Human Prion Protein's Point MutationsGiulia Rossetti and Paolo Carloni6. Prion Protein and Genetic Susceptibility to Diseases Caused by Its MisfoldingGeorge A. Carlson7. The Prion Concept and Synthetic PrionsGiuseppe Legname and Fabio Moda8. Gene Targeted Transgenic Mouse Models in Prion ResearchAbigail B. Diack, James D. Alibhai and Jean C. Manson9. Transmission and Replication of PrionsA. Marín-Moreno, N. Fernández-Borges, J.C. Espinosa, O. Andréoletti and J.M. Torres10. Immunology of Prion Protein and PrionsNeil A. Mabbott11. Phenotypical Variability in Bovine Spongiform Encephalopathy: Epidemiology, Pathogenesis, and Diagnosis of Classical and Atypical FormsCristiano Corona, Elena V. Costassa, Barbara Iulini, Elena Bozzetta, Maria Mazza, Rosanna Desiato, Giuseppe Ru and Cristina Casalone12. Scrapie, CWD, and Transmissible Spongiform EncephalopathyCandace K. Mathiason13. Infectious and Sporadic Prion DiseasesRichard Knight14. Neuropathology of Human Prion DiseasesDiane L. Ritchie and James W. Ironside15. The Structure of the Infectious Prion Protein and Its PropagationJesús R. Requena and Holger Wille16. Protein Misfolding Cyclic Amplification of Infectious PrionsFabio Moda17. Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and DisinfectantsByron Caughey, Christina D. Orru, Bradley R. Groveman, Andrew G. Hughson, Matteo Manca, Lynne D. Raymond, Gregory J. Raymond, Brent Race, Eri Saijo and Allison Kraus18. Biochemical Characterization of PrionsMichele Fiorini, Matilde Bongianni, Salvatore Monaco and Gianluigi Zanusso19. Omics of Prion DiseasesSilvia Vanni20. Therapeutic Approaches to Prion DiseasesAnnachiara Gandini and Maria L. Bolognesi21. Biosafety of PrionsEdoardo Bistaffa, Martina Rossi, Chiara M.G. De Luca and Fabio Moda
