Biologically Modified Polymeric Biomaterial Surfaces
Published on 6. December 2012
250 pages
978-94-011-1872-9 (ISBN)
Description
gap always exists between the material performance generation of new molecules along with the release during in-vivo animal tests and clinical situations, of substances from a multitude of cells. The plasma because of the difference in individual reactions proteins (including coagulation and complement proteins), the blood cells deposited on the material between one animal and another and humans. Likewise, sophisticated in-vitro and in-vivo models surface or circulating in the blood stream and their are being developed to study living body responses. released substances take part in the dynamic process of fibrinolysis and thrombus formation. Progress has been achieved in culturing mammalian cells, particularly human cells, which has lead to new in-vitro models to study cell-biomaterial Tissue response interactions. These techniques are discussed in the other chapters of this volume. Materials implanted in tissues always generate a response. The major tissue response in the extra BIOLOGICAL MODIFICATION vascular system is an inflammatory process, which may be induced chemically or physically. Many Surfaces of polymeric biomaterials may be modified proteins and cells are involved in this very complex by using a variety of biological entities (e.g.
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Erhan Piskin
Biologically Modified Polymeric Biomaterial Surfaces
Book
10/1992
Kluwer Academic Publishers
€89.13
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Content
Editorial.- Biologically Modified Polymeric Biomaterial Surfaces: Introduction.- How to Deal with the Complexity of the Blood-Polymer Interactions.- Present and Emerging Applications of Polymeric Biomaterials.- Needs, Problems, and Opportunities in Biomaterials and Biocompatibility.- Contemporary Methods for Characterizing Complex Biomaterial Surfaces.- Characterization of Biomaterial Surfaces: ATR-FTIR, Potentiometric and Calorimetric Analysis.- Surface Study of Biomaterials by Electron Induced Vibrational Spectroscopy.- Immobilization of Biomolecules and Cells on and within Polymeric Biomaterials.- Proteins at Interfaces: Principles, Multivariate Aspects, Protein Resistant Surfaces, and Direct Imaging and Manipulation of Adsorbed Proteins.- The Behavior of Proteins at Interfaces, with Special Attention to the Role of the Structure Stability of the Protein Molecule.- Adsorption, Retention and Biologic Activity of Proteins Adsorbed on Gas Discharge Treated Surfaces.- Some Model Surfaces Made by RF Plasma Aimed for the Study of Biocompatibility.- Conjugation of a Modified Form of Human C-Reactive Protein to Affinity Membranes for Extracorporeal Adsorption.- Surface Phenomena in Biocomponent-Polymer Systems: A Case Study of Mucin Adsorption on Polymers with Different Hydrophilicities.- Physical and Biological Modification of Carbonic Sorbents.- Biologically Modified PHEMA Beads for Hemoperfusion: Preliminary Studies.- Albumin Adsorption on to Large-Size Monodisperse Polystyrene Latices Having Functional Groups on Their Surfaces.- Human Cell Culture and Characterization of Cell/Biomaterial Interface.- Dependence of Endothelial Cell Growth on Substrate-Bound Fibronectin.- Surface Modification of Hydrophobic Polymers for Improvement of Endothelial Cell-SurfaceInteractions.- Proteins and Cells on Polyurethane Surfaces.- Cell Culturing on Polymeric Beads.- Effects of Biostability and Morphology on Host Response of Polyurethane-Based Soft Tissue Implants.
