
Carbohydrate Chemistry
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Content
- Carbohydrate Chemistry
- CONTENTS
- Preface
- Anomeric effects in pyranosides and related acetals
- Introduction
- The enthalpic anomeric effect
- The conformational anomeric effect
- The kinetic anomeric effect
- Conclusion
- Stereoselective synthesis of 1,2-cis-glycosylic linkages
- Introduction
- Stability of 1,2-cis-glycosylic linkages
- Factors influencing anomeric control in 1,2-cis-glycosylations
- Methods for the preparation of 1,2-cis-O-glycosides
- Methods for the preparation of 1,2-cis-C-glycosyl compounds
- Synthesis of anomeric phosphates of aldoses and 2-ulosonic acids
- Introduction
- Instalment of glycosyl phosphate linkage by glycosylation
- Synthesis of glycosyl phosphates by exposure of hemiacetals to activated derivatives of phosphoric acid
- Approaches to glycosyl phosphates based on P(III)-intermediates
- Synthesis of anomeric phosphates of aldulosonic acids
- Conclusions
- Glycosidic bicyclic lactones as new carbohydrate scaffolds
- Carbohydrate-based bicyclic lactones: an introduction
- Carboxymethyl glycoside lactones (CMGLs): synthesis
- Uses of CMGLs towards mono- and difunctional systems
- Conclusion
- Thionocarbamates on carbohydrate scaffolds-from synthesis to bioactivity
- Introduction
- Synthesis of thionocarbamates on carbohydrate scaffolds
- Reactivity of thionocarbamates on carbohydrate scaffolds
- Bioactivity
- Conclusions
- Recent advances in nitro sugar chemistry
- Introduction
- Preparation of nitro sugars
- Reactivity of nitro sugars
- Porphyrinyl-type sugar derivatives: synthesis and biological applications
- Introduction
- Synthesis of porphyrinyl-type sugar derivatives
- Biological applications
- Concluding remarks
- Sugars as chiral synthons in the preparation of fine chemicals
- Introduction
- From simple sugars to cyclic (non-sugar) derivatives: transfer of chirality
- Modified carbohydrates
- Transformation of disaccharides
- Conclusion
- Blocking the anomeric reactivity, how and why
- Introduction
- Replacement of the anomeric oxygen
- Replacement of the endocyclic oxygen
- Other modifications
- Conclusions
- Recent strategies for the preparation of C-1 glycals
- C-1 Glycals - an introduction
- From cyclic precursors
- From acyclic precursors
- Conclusions
- Glycosidases in synthesis
- Introduction
- Glycosidase as a promising tool for synthesis
- Regioselectivity of glycosidases
- Substrate specificity
- Glycosidases in industry
- Enzyme engineering-mutant glycosidases
- Conclusion
- Recent advances on the application of NMR methods to study the conformation and recognition properties of carbohydrates
- Introduction
- The access to new NMR parameters and methodological developments
- Applications: Saccharides in solution
- Applications: The interaction of saccharides with other natural and synthetic molecules
- Specificity and affinity studies in lectin/carbohydrate interactions
- Introduction
- Hemagglutination + ELLA
- Glyco chips: new tools for screening lectin specificity
- Fluorescence and fluorescence-based thermal shift assay
- NMR
- Frontal chromatography
- Quartz crystal microbalance
- Surface plasmon resonance
- Isothermal titration calorimetry
- Molecular modelling
- Concluding remarks
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