The Cat Primary Visual Cortex

Preface1 The Concept of Cat Primary Visual Cortex Prologue Milestones in the Development of the Concept of Cat Primary Visual Cortex Connections Composition of Area 17 Comparison of the Architectonics of Areas 17 and 18 and Identification of Borders Visual Maps in Areas 17 and 18 Circuitry and Signal Processing in Areas 17 and 18 Visually Guided Behavior Synthesis Recent Challenges to the Primacy of Areas 17 and 18 Epilogue2 Optical Imaging of Functional Architecture in Cat Primary Visual Cortex Introduction Methodological Aspects of Optical Imaging Optical Imaging of Functional Maps in Cat Visual Cortex Relationships between Columnar Systems Comparison with the Functional Architecture in Other Species Concluding Remarks3 2-Deoxyglucose Architecture of Cat Primary Visual Cortex Introduction Orientation Domains Ocular Dominance Domains Spatial Frequency Domains Development and Experience-Dependent Changes of Cortical Maps Advantages and Disadvantages of the 2-DG Technique Outlook4 Functional Mapping in The Cat Primary Visual Cortex Using High Magnetic Fields Introduction Limitations of Current Techniques, or Why We Need Another Mapping Technique Functional Magnetic Resonance Imaging Functional MRI of the Cat Primary Visual Cortex Conclusions5 Relationships of LGN Afferents and Cortical Efferents to Cytochrome Oxidase Blobs Parallel Processing in the Mammalian Visual System Organization of CO Staining in Cat Primary Visual Cortex Geniculate Inputs to the CO Blobs Molecular Markers for Other Blob/Interblob Inputs Outputs of the CO Blobs Projections to Area 19 Comparisons with Primates Conclusions6 INFLUENCE OF TOPOGRAPHY AND OCULAR DOMINANCE ON THE FUNCTIONAL ORGANIZATION OF CALLOSAL CONNECTIONS IN CAT STRIATE CORTEX Introduction The Vertical Meridian Rule Callosal Fibers Interlink Cortical Sites That are in Retinotopic, Rather Than Anatomical, Correspondence Interhemispheric Correlated Activity Guides Callosal Development Summary and Concluding Remarks7 Essential and Sustaining LGN Inputs to Cat Primary Visual Cortex Introduction The Reversible Inactivation Technique Two Circuits in Area 17 Area 18: More Integrative Than Area 17 Functional Architecture of Visual Cortex8 Integration of Thalamic Inputs to Cat Primary Visual Cortex Introduction Simple Receptive Fields Numerical Aspects of the Geniculocortical Projection Feedforward (Thalamic) Connections and Simple Cell Responses Intrinsic Connections and Simple-Cell Responses Conclusions9 The Emergence of Direction Selectivity in Cat Primary Visual Cortex Overview Directional Tuning: The Basics Computational Requirements for Direction Selectivity Biological Instantiation of Computational Principles Origins of Cortical Timings: The Lagged/Nonlagged Cell Model Comparison with Recent Models Intracortical Inhibition: Experimental Evidence How are Inputs Combined? Intralaminar and Interlaminar Interactions Summary and Conclusions Future Directions10 Long-Range Intrinsic Connections in Cat Primary Visual Cortex Introduction Historical Overview Layout of Long-Range Horizontal Connections Types of Neurons Forming Long-Range Horizontal Connections Synaptic Targets of Long-Range Intrinsic Connections Divergence and Convergence of Long-Range Horizontal Connections at the Ultrastructural Level Topographic Relations between Long-Range Intrinsic Connections and Functional Cortical Maps Possible Functions Plasticity of Long-Range Connections in the Adult Conclusions11 Pharmacological Studies on Receptive Field Architecture Receptive Field Architecture in Cat Striate Cortex Cells Specific Local Synaptic Input Systems to Striate Cortex Cells Striate Cortical Network Effects on RF Properties1