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An International Review Series Devoted to Proteins and Related Studies, Volume 32: Protides of the Biological Fluids documents the proceedings of the 32nd Colloquium held in 1984. This compilation is organized into three parts. Part I begins with an introduction to the defense mechanism of immunoglobulins, followed by a description of enzymes and proteins, such as lactoperoxidase and lactoferrin. The secretions that include CSF, colostrum, milk, female and male genital secretions, saliva, gastrointestinal juice, nasal and bronchoalveolar secretions, tears and synovial fluid are also elaborated. The tumor markers, which include ferritin, CEA, and TPA are dealt with in Part II. The immunotoxins, tumor imaging, and lymphoid malignancies are also covered. Part III is devoted to the advances in the separation of protides, including the staining procedure for protein detection, two-dimensional electrophoresis, and HPLC and affinity chromatography. This book is valuable to biology students and clinicians of disciplines related to advances in the protein field.
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978-1-4832-7966-4 (9781483279664)
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PrefaceAcknowledgmentsThe Thirteenth Arne Tiselius Memorial Lecture Low Molecular Weight (LMW) Urinary ProteinsSection A. Proteins in Secretions A.1. Immunoglobulins A.1.1. The Defense Mechanism A Model for Analysis of Protein Defense Mechanisms in Secretions Local Protein Synthesis and Passive Transfer in Human Body Fluid Formation Evidence for a Common Mucosal Immune System in Humans Complement Regulation in Tears A.1.2. IgA Biosynthesis of the IgA Dimer Receptor Binding of a1-Microglobulin to IgA Evidence for Migration of IgA Bearing Lymphocytes Between Peripheral Muscosal Sites Oral Adjuvants Enhance Salivary IgA Responses to Purified Streptococcus mutans Antigens IgA Antibodies to Oral and Ocular Bacteria in Human External Secretions The IgA Type Parietal Cell Antibody in Gastric Juice Molecular Analysis of Human Bile IgA IgA Dimers (D), Trimers (T) and Tetramers (Q): Transfer into Rat Bile and Reaction with Secretory Component (SC) Pathways of Polymeric IgA, Secretory Component, and Galactose-Exposing Proteins During Receptor-Mediated Endocytosis in Rat Hepatocytes: Ultrastructural Demonstration and Requirements for Intracellular Ligand Sorting Hepatic Uptake of Human Secretory IgA in Mice Secretory IgA1 and IgA2 Responses to Environmental Antigens IgA in the Bile, Saliva and Urine or Rats Changes in Size, Subclass and SC Content of Serum Immunoglobulin A in Diseases with High Polyclonal IgA Origin of IgA in Tears of Rats Androgen Regulation of IgA Levels in Tears of Rats Secretory Component and IgA in the Uterus of the Pregnant Rat Homogeneous Ig Components in Serum and Secretions of Aging C57BL/KaLwRij Mice The Wasted Mutant Mouse: A Model for the Study of IgA Deficiency in Ataxia-Telangiectasia A.2. Enzymes A.2.1. Lactoperoxidase The Peroxidase System in Human Tears The Biological Significance of Lactoperoxidase in Milk Characterization of Lactotransferrin Complexes in Human Milk Biochemical and Immunological Properties of Peroxidase from Human Parotid Saliva Some Structural and Functional Properties of Lactoperoxidase The Thiocyanate Binding to Lactoperoxidase Interactions of Sulphur in Proteins with Lactoperoxidase in the Oral Cavity A.2.2. Others Isolation of a Sputum Cysteine Protease Inhibitor Proteinases and Proteinase Inhibitors in Human Endometrial Secretion A.3. Lactoferrin Effect of Proteolysis on the Antimicrobial and Iron-Binding Properties of Human and Bovine Lactoferrins Lactoferrin as Complement Inhibitor in Synovial Fluid Effect of Enterochelin and pH on Uptake of Iron from Lactoferrin by Escherichia coli Lactoferrin and Fibronectin in Tears of Patients Undergoing Cataract Surgery A.4. C.S.F.